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Grid cell networks are impaired in a mouse model of early Alzheimer's disease

 Time of Update: 2022-05-23

In a J20 transgenic mouse model of familial AD, coding impairment of the MEC grid cell network that overexpresses aβ in the hippocampus and entorhinal cortex .
Pharmaceutical companies start the "buy, buy, buy" model to ease the "mid-life crisis"

 Time of Update: 2022-05-23

For example, on the morning of February 28, 2022, Huadong Medicine announced the acquisition of a partial stake in Heidelberg Pharma, a German listed pharmaceutical company, and signed an exclusive license agreement with it .
JTO: Professor Fang Wentao's team released the world's first postoperative recurrence prediction model for thymoma

 Time of Update: 2022-05-20

authoritative academic journal in the field of thoracic oncology. Research results: "Recurrence prediction model of thymoma and its significance for postoperative management : China Thymoma
Xu Shuhua's team released the ArchaicSeeker2.0 method to reconstruct the analysis process of the ancient human gene communication model

 Time of Update: 2022-05-20

)" and other funds . >Paper link: https://star-protocols. cell. com/protocols/1572> > >
Br J Cancer: A predictive model that predicts responsiveness to neoadjuvant therapy in patients with rectal cancer

 Time of Update: 2022-05-19

The model used MRI-based radiomics (MBR) features based on T2-weighted images (T2WI), clinical baseline characteristics, and neoadjuvant therapy modalities to stratify LARC patients .
A new discovery has been made in the investigation of the "star plant" Yangbi maple, which is a very small population

 Time of Update: 2022-05-19

Among them, the Yangbi maple species found in the Laojun Mountain National Nature Reserve in Wenshan is the largest, with about 80 plants, and the largest diameter at breast height is 133cm .
BPC guest lineup "star" force announced, promoting the acceleration of innovation of original research drugs

 Time of Update: 2022-05-18

>Shi Jun, School of Life Science and Technology, Kunming University of Science and Technology, Ph . Vice President Li Jingrong, CTO of Jinfang Pharmaceutical, General Manager
National Medical Insurance Bureau: In-hospital marketing model of consumables has completely changed

 Time of Update: 2022-05-17

compared to competing products, bear the brunt of the consumables that hospitals are the first to "abandon" . The change of hospital business model brings new challenges to dealers For medical
China's century-old anti-epidemic history "stars are shining"

 Time of Update: 2022-05-17

" of countless schistosomiasis - Oncomelania was born . At that time, the snail area in Qingpu was more than 74. 29 million square meters, accounting for 16. 3% of the local land
The Medical Insurance Bureau issued a notice that there have been new changes in the marketing model of machinery companies

 Time of Update: 2022-05-15

/> Connecting the National Unified Medical Insurance Information Platform to Affect All Machinery Companies As the saying goes, the reform of the national medical insurance payment method depends on Zhejiang, and the model of Zhejiang's medical
Lancet rheumatology: STAR pathway of care in patients with pain 3 months after total knee

 Time of Update: 2022-05-14

Patients with chronic pain 3 months after total knee replacement surgery were randomly assigned (2:1) to receive the Post Replacement Support and Therapy (STAR) pathway of care plus usual care, or to receive usual care alone .
Ke Yang's team released a new version of the risk diagnosis model for early screening of esophageal malignant lesions in the Chinese population

 Time of Update: 2022-05-14

screening and monitoring management to achieve "precision" and "individualization" of screening, reduce resource consumption and greatly improve the detection rate of malignant lesions. important direction of work development
Development and initial validation of the Sjögren's Syndrome Response Assessment Tool (STAR

 Time of Update: 2022-05-14

validation of STAR followed the OMERACT (Outcome Measurements in Rheumatology) guidelines14 and consisted of three steps (Figure 1), combining a data-driven approach (Table 1) and a consensus approach from nine RCTs
A&R: Impact of impaired T-cell receptor signaling on gut microbiota in a mouse model of systemic autoimmunity

 Time of Update: 2022-05-13

B6SKG mice had altered gut microbiota that was associated with the expansion of segmented filamentous bacteria and the development of SLE by driving Th17 cell differentiation , which in turn was impaired by IL-17 deficiency .
Over $9 billion of star drug Qilu is the first to report production in China

 Time of Update: 2022-05-12

com, the sales of aflibercept intraocular injection solution in public medical institutions in China will exceed 600 million yuan in 2021, a year-on-year increase of nearly 60% .
in dynamic process analysis and data-driven modeling of phototherapy

 Time of Update: 2022-05-11

>　　Calculating the production of singlet oxygen during PDT
Guangzhou Health Center has made new progress in the construction and application of primary liver cancer model

 Time of Update: 2022-05-11

>. >　　Paper link>　　>　　Guangzhou Health Center has made new progress in the construction and application of primary liver cancer model>　　>　　>
Science: Using CRISPR to build a melanoma model from scratch

 Time of Update: 2022-05-11

is the first time scientists have used precisely controlled genetic engineering to create a human cancer model from fully differentiated or specialized cells, rather than stem cells, said Eran Hodis, first author and one of the corresponding authors
stress model rats—regulates cecal flora and inhibits NLRP3 inflammasome to reduce cecal mucosal damage

 Time of Update: 2022-05-10

and CUS perturbing the cecal biomarker microbiota . SHD regulates CUS-induced overexpression of NLRP3, ASC, caspase-1, IL-1β, and IL-18 in serum and cecal mucosa
In order to speed up the "return of blood", many pharmaceutical companies started the "selling, selling and selling" model during the year

 Time of Update: 2022-05-10

　　[Pharmaceutical Network Industry News] Sihuan Pharmaceutical announced on the evening of April 18 that Hainan Sihuan Pharmaceutical, a wholly-owned subsidiary of the company, plans to sell the entire issued share

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