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Good news: ADAPT+ research results debut at AAN conference, efgartigimod is also effective and safe for long-term treatment of myasthenia gravis!

 Time of Update: 2022-06-10

The results of the ADAPT+ study can preliminarily demonstrate that long-term treatment with efgartigmod has good efficacy in both AChR antibody-positive and negative gMG patients, providing sustained and reproducible clinically meaningful improvements in function and strength, while maintaining good tolerance.
bone metastases, apalutamide + ADT brings PSA deep response, long-term tumor control effect is obvious classic case

 Time of Update: 2022-06-05

During the patient's treatment, the symptoms related to bone metastases and primary lesions were significantly improved, highlighting the excellent efficacy and safety of ADT + apalutamide combination therapy .
Cardiovasc Diabetol: Effects of long-term metformin administration on cardiac troponin levels in diabetic patients

 Time of Update: 2022-05-11

with chronic type 2 diabetes who were randomly assigned to receive either metformin (850 mg, 3/day) or placebo, along with insulin . The subjects' cardiac troponin I and T levels were measured
, found that long-term low-dose garlic intake can effectively reduce total cholesterol, LDL cholesterol and inflammation

 Time of Update: 2022-05-08

In-depth data analysis of 22 recent randomized controlled trials since 1990 found that long-term low-dose garlic intake was effective in reducing total cholesterol , low-density cholesterol and inflammatory markers .
J Clin Oncol: Replacing CT with MRI and lengthening the follow-up interval have no adverse effect on long-term outcomes in patients with stage I seminoma

 Time of Update: 2022-04-23

The TRISST trial was a noninferiority, phase 3 factorial trial designed to assess whether the use of magnetic resonance imaging (MRI) or reduced frequency of scans did not increase the rate of late recurrence .
Blood: Effects of FLT3 inhibitor Gilteritinib vs salvage chemotherapy on long-term outcomes in patients with relapsed/refractory AML

 Time of Update: 2022-04-22

Chemotherapy combination) significantly improved the survival rate and remission rate of AML patientsThe randomized phase 3 ADMIRAL trial compared gilteritinib with salvage chemotherapy in patients with FLT3 mutation-positive (+) relapsed or refractory AML .
Diabetes: Long-term effects and clinical predictors of acute kidney injury on the progression

 Time of Update: 2022-04-21

Serum Uric Acid (SUA) To assess the long-term impact of acute kidney injury (AKI) on the progression of diabetic nephropathy (DKD) and all-cause mortality, and to investigate the determinants of AKI in Chinese patients with type 2 diabetes (T2D) .
Express reduced the bleeding rate by 85%, and the long-term effect of the phase 3 clinical trial of hemophilia gene therapy was positive

 Time of Update: 2022-02-23

The trial results showed that patients who received a single gene therapy treatment had an 85% reduction in annual bleeding rate (ABR) from baseline after two years of treatment, which was superior to coagulation factor VIII prophylaxis .
the protective effect of HMCES on long-term hematopoietic stem cells and propose new targets for leukemia treatment

 Time of Update: 2022-02-21

Therefore, the protection of AP sites on single-stranded DNA by HMCES and the regulation of DNA damage repair pathways jointly ensure that LT-HSCs maintain genome stability and self-renewal capacity during stress hematopoiesis .
The Lancet: Long-term study suggests oral peanut immunotherapy may be more effective in children under four with peanut allergy

 Time of Update: 2022-02-19

desensitization (safe intake of 5,000 mg of peanut protein powder in a food challenge following a two-and-a-half-year daily treatment period under the supervision of the investigator) and remission (26 after treatment ended). Weeks can repeat
AIDS: Long-term effects of iloyoumab in patients with HIV and dyslipidemia

 Time of Update: 2022-02-17

, the effect of monthly subcutaneous injection of ilovolumab 420 mg on LDL-C levels after 24 weeks in HIV carriers with hypercholesterolemia/mixed dyslipidemia, and statistical emergent adverse events (TEAEs) .
Express reduced the bleeding rate by 85%, and the long-term effect of the phase 3 clinical trial of hemophilia gene therapy was positive

 Time of Update: 2022-01-26

Results of the trial showed that patients who received a single gene therapy treatment had an 85% reduction in annual bleeding rate (ABR) from baseline after two years of treatment, which was superior to coagulation factor VIII prophylaxis .
5-year long-term effect observation of BioMarin's hemophilia gene therapy phase III clinical trial, with positive data

 Time of Update: 2022-01-23

Trial results showed that in 112 subjects (median follow-up of 110 weeks), valoctocogene roxaparvovec reduced the patient's annual bleeding rate (ABR) by 85% compared to a baseline value of 4.
Circ-Heart Fail: The effect of Tafamidis on the long-term survival of patients with transthyretin amyloid cardiomyopathy

 Time of Update: 2022-01-08

cardiomyopathy patients who have completed the ATTR-ACT trial can participate in the long-term extended analysis (LTE), continue to use the same Tafamidis dose, or randomize (2:1) if they have received placebo treatment before 80 Or 20mg Tafamidis
GUT: Long-term effectiveness analysis of stool immunochemical test for screening proximal and distal colorectal cancer

 Time of Update: 2021-12-27

Therefore, this study aims to measure the impact and long-term effectiveness of fecal immunochemical testing (FIT) on colorectal cancer (CRC) screening.
Can wolfberry be eaten for a long time? Will there be side effects if I eat too much?

 Time of Update: 2021-12-26

Therefore, regular consumption of wolfberry can nourish the liver, nourish the kidneys, nourish the lungs, invigorate deficiency and essence, clear away heat and improve eyesight.
Nature: One-time medication, long-term protection, the AIDS drug candidate developed by Gilead has significant effects in primates

 Time of Update: 2021-12-25

On December 7, 2021, researchers from Harvard Medical School and Gilead Sciences published a research paper titled: Long Acting Capsid Inhibitor Protects Macaques From Repeat SHIV Challenges in Nature .
long-term immune memory, and the effect of the vaccine may be strengthened!

 Time of Update: 2021-12-08

the target virus SARS-CoV-2 that caused the new coronavirus is to establish immune memory . Generally speaking, immune memory is that when the human body is infected with a virus
Gene therapy for hemophilia A achieves long-term curative effect

 Time of Update: 2021-12-06

side effects, 17 of which were related to AAV vector infusion, mainly including fever, muscle pain, and vomiting, and 7 patients had elevated liver transaminases, which improved after treatment .
CCSC: Good news spreads frequently, long-term benefit, CAR-T curative effect sees the truth

 Time of Update: 2021-12-05

-edge topics in the therapeutic field, we will conduct in-depth discussions and exchanges on Fosun Kate’s CAR-T cell therapy drug Yikaida® (Akirensai Injection) . Below, I

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