The novel interaction and catalytic mechanism of the new ubiquitin sidE and ubiquitin and its ligands.
Time of Update: 2020-08-10
have evolved a variety of ways to interfere with the host's ubiquitin modification system, so as to enhance the efficiency of infection and avoid immune surveillance. previously reported ubiquitization modifications (whether the host itself
The first phase of "recombinant human tumor necrosis factor related apoptosis inducing ligand for injection" was completed
Time of Update: 2020-04-03
On March 24, humanwell said at the 2013 performance presentation meeting that the first class new drug "recombinant human tumor necrosis factor related apoptosis inducing ligand
reveal the ligand effect in manganese catalytic hydrogenation: mechanism research and Application
Time of Update: 2019-10-25
Catalytic hydrogenation has been widely used in organic synthesis and chemical production, which usually requires the use of precious metal catalysts to promote the smooth
ACS catalyst: Heterocyclic C-N coupling reaction catalyzed by Ni optimized by ligand design
Time of Update: 2019-09-29
(hetero) aromatic amines and N-arylated heterocyclic compounds have great application space in bioactive molecules, functional materials and other fields
of nonactivated olefins induced by a novel monodentate oxazoline ligand
Time of Update: 2019-09-28
Introduction: the traditional olefin functionalization reaction mainly involves the reaction of activated olefin substrate and organometallic reagent, which greatly limits
Angelw: derivative ligands regulate the electronic structure of gold nanoclusters
Time of Update: 2019-09-03
Gold nanoparticles have been widely used in photocatalysts, photovoltaic devices, chemical sensors and nonlinear optical media due to their atomic accuracy
of phosphine ligands derived from the framework of anthracene photodimers in palladium catalyzed coupling reaction
Time of Update: 2019-08-30
Recently, the research group of Conghuan, Institute of physics and chemistry, Chinese Academy of Sciences, has made new progress in the design of novel phosphine ligands for palladium catalyzed coupling reactions (org.
"sulfur" -- palladium catalyzed asymmetric carbonyl thioesterification of olefins promoted by chiral SOP ligands
Time of Update: 2019-07-30
Liao Jian's research team envisions whether the chiral sulfoxide phosphine (SOP) ligands developed by the research team can be used to realize palladium catalyzed asymmetric carbonylation of olefins under mild conditions (Fig. 1b).
JACS: ligand regulated IR catalyzed regionally divergent hydroxylation of unactivated olefins
Time of Update: 2019-07-25
Due to the abundant adjacent n, O structures and many available olefin precursors in bioactive natural products and drugs, the regioselective and stereoselective hydroxylation
: Study on the cobalt catalyzed hydrosilylation of martensite promoted by rigid pyridine-cycloalkylimine ligands
Time of Update: 2019-07-23
Therefore, based on the rigid pyridylcycloalkylimine ligands developed by his research group, the author has carried out the study of cobalt catalyzed hydrosilylation and made a new breakthrough, with the reaction of ton as high as 4950.
of aryl ethylene and benzothiazole with N-heterocyclic carbene ligands
Time of Update: 2019-07-02
Author: with the increasingly serious environmental and resource problems, the development of green and efficient C-C bond formation method has become one of the most cutting-edge
"Rhodium" and "sulfur" - ligand promoted Rh (III) - catalyzed C-H bond sulfurization
Time of Update: 2019-05-22
Recently, Professor Sun Weiyin, associate professor of Luyi, School of chemistry and chemical engineering, Nanjing University, and Professor Yu Jinquan of Scripps Research
Acc. chem. Res.: asymmetric catalytic reactions involving p-chiral phosphine ligands based
Time of Update: 2019-04-20
Res.) in view of the fact that most p-chiral phosphine ligands are sensitive to air and have poor reactivity and selectivity in asymmetric catalysis, it is necessary to design p-chiral ligand framework suitable for various reactions of diphosphones and monophosphones.
Enantioselective C-H alkylation of Aniline Derivatives Catalyzed by JACS: Pd / s, O ligands
Time of Update: 2019-04-11
The reaction of n-benzylaniline derivatives 1q-1v, which were substituted by methyl, methoxy, chlorine, trifluoromethyl, ester and carbonyl, showed excellent para selectivity, and p-alkenylation products were obtained in good yield (47-70%).
Angelw, Li Zhengming group and ye mengchun group, Nankai University: ligand promoted hydrofluorination of olefins catalyzed by iron
Time of Update: 2019-04-04
Int. ed.) recently, Li Zhengming and ye mengchun of the National Key Laboratory of elemental organic, Nankai University successfully realized the iron catalyzed hydrofluorination of olefins (Fig. 1c) by designing a new reaction strategy.
Nano letter, Yuanzhi research group, Nankai University: pH sensitive reversible double ligand
Time of Update: 2019-03-19
This shows that PBA / gal micelles have reversible pH sensitive double ligand masking / de masking effect, which can enhance the uptake of micelles by tumor cells and significantly reduce the uptake of micelles by macrophages at pH 7.4.
isomerization of alkynes and asymmetric synthesis of 2,5-dihydrofuran catalyzed by chiral bifunctional phosphine ligands / gold
Time of Update: 2019-03-10
In general, chiral TERT propargyl alcohol derivatives have good tolerance to steric hindrance, and excellent yield and enantioselectivity can be obtained.
tuning the pore size of rigid zif-8 membrane with electric driven mixed ligand strategy
Time of Update: 2019-02-02
Since the 21st century, due to the increasing consumption of non renewable energy such as coal, oil and natural gas and the decreasing storage, people are increasingly aware
New achievements of Professor Deng Hexiang's team in MOF materials research: from cheap small ligands to super large mesoporous MOF
Time of Update: 2019-01-08
Recently, Professor Deng Hexiang's team from school of chemistry and molecular science of Wuhan University has made the latest achievements in the field of synthesis and design of mesoporous (pore size > 2 nm) mesoporous metal organic framework (MOF).
Research progress of F-region metal ligand multiple bond by Professor Zhu Congqing of Nanjing University
Time of Update: 2018-12-28
Recently, Professor Zhu Congqing's research group of School of chemistry and chemical engineering of Nanjing University has made progress in the research of metal ligand multiple