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Cell sub-issue: Chen Sidi's team uses CRISPR screening to discover new ways to enhance the effect of CAR-T
Time of Update: 2022-04-23
On March 10 , 2022 , the team of Associate Professor of Genetics at Yale University, Sidi Chen , published a paper entitled: A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance Research paper on CAR-T therapy .
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Cell Metabolism: Chen Sidi's team used CRISPR screening to discover new ways to enhance the effect of CAR-T
Time of Update: 2022-04-23
On March 10, 2022, the team of Associate Professor of Genetics at Yale University, Sidi Chen , published a paper entitled: A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance Research paper on CAR-T therapy .
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Cell Sub-Journal: CRISPR screening tool to identify new drug targets for leukemia
Time of Update: 2021-08-26
According to a new study published by Penn Medicine on the Molecular Cell website, the CRISPR screening tool has identified a new therapeutic target for the treatment of acute myeloid leukemia (AML).
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Br J Cancer: CRISPR/Cas9 Genome-wide Functional Loss Screening Technology identifies
Time of Update: 2020-10-12
study aims to identify cytokines that affect schoinib resistance using CRISPR/Cas9-based high-volume loss of function (LOF) screening techniques.
, the results show that CRISPR/Cas9 LOF screening technology is a promising method that can be used to identify and target cytokines associated with resistance to anti-cancer drugs.