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Cancer Cell: The molecular mechanism of key protein-mediated tumor immune tolerance

 Time of Update: 2021-04-18

023 Original source: Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance.
CTM Journal | The clinical application of the characteristics and dynamic changes of plasma ctDNA

 Time of Update: 2021-04-18

So far, a variety of HER2 targeted drugs have been developed, including HER2 antibody and its derivatives (trastuzumab and pertuzumab), tyrosine kinase inhibitors (lapatinib, niratinib and Afatinib, etc.
Bispecific fusion protein treatment of metastatic uveal melanoma significantly improves overall response rate

 Time of Update: 2021-04-18

is a new type of bispecific fusion protein, which is formed by fusion of soluble TCR and anti-CD3 immune effector domain. The fusion protein can target a lineage antigen gp100 expressed in melanocytes and melanomas, redirect and Activate T cells
What makes the protein channel open and close

 Time of Update: 2021-04-17

Image source: Rockefeller University MSCS channel protein (pink) and its related lipids (dark green, light green, red) are embedded in nanodiscs (gray).
JAHA: The relationship between plasma omega-3 fatty acids and the risk of cardiovascular events in patients with acute coronary syndrome

 Time of Update: 2021-04-17

In patients with acute coronary syndrome , long-chain ω3-PUFA in plasma is negatively correlated with the reduced probability of sudden cardiac death, but has nothing to do with traditional risk factors and blood lipids.
JCEM: The relationship between plasma cortisol and the risk of atrial fibrillation

 Time of Update: 2021-04-17

1210/clinem/dgab219" target="_blank" rel="noopener">Plasma Cortisol and Risk of Atrial Fibrillation: A Mendelian Randomization Study .
The mechanism of protein deacetylase regulating ribosomal protein revealed

 Time of Update: 2021-04-16

html" class="zdbq" title="Bio-related food information" target="_blank">organisms reported the effects of histone deacetylase of ribosomal protein acetylation and its regulatory function.
Nutrients: Adaptable changes in intestinal flora and metabolism in patients with chronic kidney disease on a low-protein diet

 Time of Update: 2021-04-16

, Compositional and Functional Adaptations of Intestinal Microbiota and Related Metabolites in CKD Patients Receiving Dietary Protein Restriction .
protein-cod protein synergistically regulates the nutritional and functional properties of the framework structure

 Time of Update: 2021-04-16

to more than 90%. Spectroscopic studies have shown that the spatial structure of RPs and CPs unfolds at pH 12, and their secondary structure undergoes a sheet-helix structural transformation under the protein-protein interaction
Assess the neutralization potential of restorative plasma against variant new coronaviruses | "Nature" paper

 Time of Update: 2021-04-14

A study published online by "Nature" Escape
Livzon Bio: Jointly developed recombinant new coronavirus fusion protein vaccine enters clinical trials

 Time of Update: 2021-04-14

Recently, the recombinant novel coronavirus fusion protein vaccine (project code: V-01) jointly developed by the Institute
of the protein machine LolCDE, systematically revealing the recognition and transport mechanism of the outer membrane lipoprotein of Gram-negative bacteria

 Time of Update: 2021-04-14

Responsible Editor | xi At present
J Gastroenterology: Lactobacillus stress protein GroEL can prevent colon inflammation

 Time of Update: 2021-04-13

?w=%E6%BA%83%E7%96%A1%E6%80%A7%E7%BB%93%E8%82%A0%E7%82%8E">ulcerative colitis , usually shows the phenomenon of chronic colon inflammation. Immune
my country's recombinant protein new coronavirus vaccine clinical trial results released

 Time of Update: 2021-04-13

" . The results showed that the safety of the vaccine is good. 97% of the participants who received 3 doses of 25 micrograms vaccine produced neutralizing antibodies that can block the live virus, and the level
Br J Cancer: Down-regulation of ITGA6 expression enhances the invasiveness of multiple myeloma and promotes its development into plasma cell leukemia

 Time of Update: 2021-04-13

>The study analyzed the gene expression profiles of MM patients and PCL patients to identify molecular differences between the two diseases. Through Cox survival curve and Kaplan-Meier analysis, the impact
Restorative plasma may have the potential to fight new coronavirus variants

 Time of Update: 2021-04-13

-height: 30px"> Restorative plasma may have the potential to fight new coronavirus variants
New crown recombinant subunit protein vaccine: precise identification of the core part of the virus

 Time of Update: 2021-04-13

In terms of effectiveness, the results of the two phases of clinical trials have shown that the vaccine produces twice as much neutralizing antibodies as patients who have recovered from new coronary pneumonia.
FSHW: The effect of xanthan gum on the quality of low-sodium salted beef and the characteristics of myofibril protein

 Time of Update: 2021-04-07

gum, as an anionic polysaccharide, can improve the water holding capacity and elasticity of meat products, and reduce the cooking loss and hardness of meat products. These characteristics have
Science and Technology of Jiangnan University: Rice protein-cod protein synergistically regulates

 Time of Update: 2021-03-30

be weakened Calcium bridge, thereby promoting the water stability of CPs, forming a composite material with high water solubility. The light scattering data indicated that CPs were grafted
Nat Commun: Iron-regulated microtubule cytoskeleton protein can be a potential target for the treatment of iron-restricted anemia

 Time of Update: 2021-03-30

The results of this study found the cytoskeleton components in the iron restriction response of red blood cells and confirmed its potential for targeted therapy in ACDI.

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