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NEJM: Lumasiran, an interfering RNA for the treatment of primary type 1 hyperoxuria
Time of Update: 2021-04-13
>Primary type 1 hypergrassuria (PH1) is a rare genetic disease. Excessive hepatic oxalate secretion leads to kidney stones, nephrocalcinosis, renal failure, and systemic oxalic
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regulatory role of non-coding RNA in the process of plant immunity
Time of Update: 2021-03-27
immune response. In addition, the review also discussed the regulatory role of cross-border mobile small RNAs in the interaction between plants
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Researchers reveal that RNA virus polymerase has a characteristic region related to host adaptation
Time of Update: 2021-03-25
, PLoS Pathogens 2020), and in collaboration with the team of Wuhan Institute of Virology researcher Zhang Bo, systematically revealed the conformational diversity and conservation of NS5 and the molecular mechanism of MTase regulating RdRP (Li et al.
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The RNA virus polymerase revealed by Wuhan virus has a characteristic region related to host adaptation
Time of Update: 2021-03-25
Gong Peng’s team, a researcher at the Wuhan Institute of Virology, Chinese Academy of Sciences, has long been engaged in the study of the catalysis and regulation mechanism of viral RdRP.
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Eat melon, the new coronavirus RNA will be integrated into the human genome?
Time of Update: 2021-03-25
In order to experimentally confirm the possibility of viral reverse transcription integration, the research group described that SARS-CoV-2 RNAs can be reverse transcribed in human cells by reverse transcriptase (RT) from the LINE-1 element or HIV-1 RT.
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Small cells, big impact: RNA-protein complexes in cyanobacteria
Time of Update: 2021-03-25
Scientific question: What are the RNA-binding proteins involved in important post-transcriptional regulation processes in cyanobacteria that have not been clearly studied in other bacteria?
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Using HBV RNA to predict the efficacy of peginterferon in the treatment of chronic hepatitis B | Research Express
Time of Update: 2021-03-22
Figure 1 The relationship between HBV RNA response rate and sustained virological response and HBsAg loss at 24 weeks of treatment.
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Acta Neuropathologica: Huntington's disease brain-derived small RNA reproduces the main pathological features of Huntington's disease in young mice
Time of Update: 2021-03-21
In summary, the results of this study indicate that HD-sRNA derived from human putamen can trigger abnormal motor coordination in young mice and reproduce the main pathological features of HD.
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JACC: Double-stranded small interfering RNA Inclisiran can effectively reduce low-density
Time of Update: 2021-03-20
>>>ORION-9 Inclisiran trial evaluated the effects of treatment of heterozygous familial hypercholesterolemia (HeFH) LDL-C patient
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Chinese scientists discover a new mechanism for RNA modification to regulate chromatin
Time of Update: 2021-03-17
of RNA methylation
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The new Scissors can temporarily edit RNA
Time of Update: 2021-03-16
recently, a new system that allows the editing of RNA came into view, expanding the editable range of CRISPR editing tools and greatly improving the ability to target disease-related gene mutations.
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RNA interference found to be 'umbrella' for early human neurodevelopment
Time of Update: 2021-03-15
that human neuroresurger cells can use RNA to interfere with antiviral immunity against Zika virus infection, according to a new study by researchers in China. The study is the first to find the crucial role of RNA in the development
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Scientists have revealed the important function of ring RNA in natural immunity
Time of Update: 2021-03-15
of stem ring structure" make them play an important role in regulating immune stabilization. study provides the basis for the study of the metabolism and function of ring RNA in natural immunity and provides new ideas for the clinical diagnosis
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Scientists use RNA as a template for ionizing recombination repair in plants
Time of Update: 2021-03-15
herbicide-like herbicide rice plant for future generations using nuclear enzyme self-cutting and gene editing systems with RNA/DNA dual cutting capabilities, respectively. For the first time in plants, RNA is used as a template for isoogeneic
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Scientists have mapped the most accurate human RNA molecule m6A modification
Time of Update: 2021-03-14
machine learning techniques to train predictive models through existing features, which provided more reliable reference information for future research in the field of human RNA modification. (Source: Xinhua News Agency,
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Messy RNA can't stop the "dance step"
Time of Update: 2021-03-11
to better explore the secrets of Huntington's disease, the Heiman team used two different screening techniques, TRAP for mouse models, and single-core RNA sequencing for mice and people.
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Major and Modified Nucleosides, RNA, and DNA
Time of Update: 2021-03-06
HPLC has proved to be a very effective, broadly applicable chromatographic method for the separation and analysis of complex molecules in fields as diverse as biochemistry and environmental, pharmaceutical, medical, and polymer chemistry.
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Isolation of Plant RNA
Time of Update: 2021-03-06
( 1 ), involves grinding and phenol extraction of plant material followed by differential precipitation of RNA with sodium acetate.
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Using RNA Interference in Schistosoma mansoni
Time of Update: 2021-03-05
These methods include isolating and culturing the parasites, preparing and delivering dsRNA targeting a specific gene and monitoring the outcome.
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Biosynthetic thinking of RNA
Time of Update: 2021-03-05
2, RNA polymerase composition and its role?
5, what is enzyme RNA and what is the significance of their discovery?
