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The State Food and Drug Administration revises the drug insert of the children's phlegm-relieving and cough-relieving preparations

 Time of Update: 2022-04-23

The item [adverse reactions] should include: Monitoring data show that children's anti-phlegm and anti-cough preparations have vomiting, nausea, diarrhea, abdominal pain, rash, itching, sweating, dizziness, Headache, allergic reaction and other adverse reaction reports .
"Inadvertently inserted" Sildenafil - the unexpected joy of side effects research

 Time of Update: 2022-01-25

Members of the Pfizer research team hypothesized that if PDE5 plays an important role in the physiology of corpus cavernosum smooth muscle, it is likely that administration of sildenafil may promote erectile responses to sexual stimulation .
Announcement of the State Food and Drug Administration on Revising the Drug Insert for Alocillin Sodium for Injection (No. 108 of 2021)

 Time of Update: 2021-11-14

the contents of the instructions for azlocillin sodium for injection . The relevant matters are hereby announced as follows: 1. The marketing authorization holders of the above-mentioned
Announcement of the State Food and Drug Administration on Revising the Insert Sheets of 4 Kinds

 Time of Update: 2021-11-14

: 1. The marketing authorization holders of the above-mentioned drugs shall submit to the provincial drug supervision before September 28, 2021, in accordance with the "Administrative Measures for Drug Registration" and other relevant
Xiong Wei's research group from the School of Life Sciences published a report on a mouse model of deafness caused by ectopic insertion of a retrotransposon

 Time of Update: 2021-10-21

>The middle-stage endolymph of the cochlea is secreted by the stria vascularis tissue and maintains its components, such as a potassium ion concentration of 150 millimol and an intracochlear potential of 80 millivolts. Therefore, research
Scientists develop high-performance large fragment insertion and deletion variant identification tools

 Time of Update: 2021-10-19

> Scientists develop high-performance large fragment insertion
Takeda’s EXKIVITY™ (mobocertinib) became the first oral treatment approved by the US FDA for patients with EGFR exon 20 insertion + NSCLC

 Time of Update: 2021-09-29

be sold under different trademarks, or used for different diseases, or in different dosages, or have different effects . Any information contained in this article should not be regarded as an application
Thyroid: Patients with Graves ophthalmopathy use prostaglandin F2-α eye drops (bimatoprost)

 Time of Update: 2021-09-29

In inactive GO, treatment with bimatoprost for more than 3 months does not improve exophthalmos .
cell lung cancer with exon 20 insertion mutations: the results of the initial analysis of the phase I study CHRYSALIS

 Time of Update: 2021-08-13

In summary, Amivantamab has shown good anti-tumor activity and safety in the treatment of platinum-based non-small cell lung cancer (NSCLC) patients with EGFR 20 exon insertion mutations .
Urinary tumor-related drugs: the 2021 version of the drug catalog of the super drug insert

 Time of Update: 2021-08-09

, including the indications for the use of the drug, the applicable population, the method of administration, or the usage where the dosage is not within the insert approved by the domestic drug regulatory authority .
CRISPR technology knocks out PD-1, and the targeted insertion of CD19 CAR-T completes the first patient's drug delivery. Medical Meng broke the news

 Time of Update: 2021-08-09

Caribou was co-founded by Nobel Laureate Professor Jennifer Doudna, aiming to use RNA-DNA hybrid sequence-mediated CRISPR gene editing system (chRDNA) to develop allogeneic cell therapy with potentially transformative effects on patients . https:// -trial-evaluating-cb-010-a-crispr-edited-allogeneic-anti-cd19-car-t-cell-therapy-in-patients-with-relapsed-or-refractory-b-cell-non-hodgkin-lymphoma /2.
The first insertion mutation therapy targeting EGFR/HER2 Exon20 was declared and listed in China and included in the priority review at the same time

 Time of Update: 2021-08-09

>. It is the first domestic application for the treatment of EGFR exon 20 (Exon20) insertion mutation NSCLC therapy. At the same time, the market application of this product was also included
3 cm of fish bones penetrated the stomach wall and inserted into the pancreas to cause inflammation. Digital navigation helps to uncover the "true culprit"

 Time of Update: 2021-08-02

>. >>Preoperative CT showed that the fish bone has been inserted into the pancreas>Preoperative CT shows that the fish
Junshi Bio: EGFR exon 20 insertion and other rare mutation inhibitor JS111 was approved for trial

 Time of Update: 2021-07-25

/>. Uncommon EGFR mutations account for about 10% of all EGFR mutations, including EGFRexon 20 insertion, T790M primary point mutation and compound mutation, and G719X represented by the board of directors of the company
Announcement of the State Food and Drug Administration on the revision of the drug inserts of 14

 Time of Update: 2021-07-08

Compound Paracetamol and Renin Tablets, Aminocahuangmin Oral Solution, Paracetamol and Pseudoephedrine Dispersible Tablets (Ⅲ), Pediatric Paracetamol and Namin Tablets, Pediatric The drug inserts of 14 varieties including Paracetamol Huang Namin Tablets
Missing became the first drug approved to treat NSCLC with EGFR exon 20 insertion mutation!

 Time of Update: 2021-06-30

> Mutations in the EGFR tyrosine kinase region mainly occur in exons 18-21, among which exon 19 deletion mutation (19del) and exon 21 point mutation (21L858R) are two relatively common forms of mutations, which account for approximately In 90% of the total
Takeda reported the latest results of mobocertinib, further confirming the clinical benefits of patients with EGFR exon 20 insertion + mNSCLC

 Time of Update: 2021-06-10

( TSE:4502/NYSE:TAK ) ("Takeda") today released mobocertinib (TAK-788) for oral treatment of epidermal growth factor receptor (EGFR) Exon 20 insertion mutation positive (insert+) metastatic non-small cell lung cancer (m NSCLC ) Phase 1/2 clinical trial data.
Cell: Unintentionally inserting willows into shade!

 Time of Update: 2021-05-22

On April 28, 2021, Lin Tian’s research team developed a 5-HT2AR ligand fluorescent receptor psychLight2 with millisecond time resolution on the basis of dLight1 in Cell magazine, and discovered a class of non-psychotic, potent antidepressant effects Compound AAZ-A-154.
The State Food and Drug Administration revised the drug inserts for tramadol suppositories and compound preparations

 Time of Update: 2021-05-02

The use of this product during lactation may lead to the risk of serious adverse reactions in breastfed infants, including excessive sleepiness, difficulty in breastfeeding, or may cause severe breathing problems or even death.
The State Food and Drug Administration revised the drug inserts for tramadol suppositories and compound preparations

 Time of Update: 2021-04-18

, bradycardia, lower blood pressure (such as orthostatic hypotension), increased blood pressure, cyanosis, flushing. >Immune dysfunction and infection: allergic-like reactions, allergic reactions, anaphylactic shock

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