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Promoting the development of precision medicine AI-driven single-cell analysis platform receives US$73 million
Time of Update: 2022-04-30
The company's technology platform combines AI, proprietary microfluidics, high-resolution optics, and a growing cell atlas, which contains more than 1 billion visual feature-based images to analyze and classify cells, according to the press release .
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Progress in the analysis of single-cell transcriptome and developmental trajectories of early mouse embryonic inner ear ganglion cells
Time of Update: 2022-04-29
Although mature inner ear vestibular ganglia and spiral ganglia have different functions, they both originate from early embryonic otic capsule neuroblasts, also known as cochlear vestibular ganglion precursor cells (CVGs) .
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2022 The role of EBMT hematopoietic stem cell transplantation in mantle cell lymphoma: results of a single-center exploratory study
Time of Update: 2022-04-28
The early group planned to use autologous HSCT as consolidation therapy, but this regimen was not feasible due to poor patient condition or mobilization .
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2022 EBMT Voice of China Prolonged cyclophosphamide infusion time as a stem cell mobilization
Time of Update: 2022-04-28
>The First Affiliated Hospital of Sun Yat-Sen University conducted a study to evaluate the efficacy and safety of two different infusion times of Cy + G-CSF for peripheral blood stem cell mobilization in patients with newly
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Demystifying the pathogenesis of aortic dissection from the perspective of single cells
Time of Update: 2022-04-26
>. Through single-cell transcriptome sequencing and immunomulticolor staining technology, this project first described the composition and spatial location of cell subsets in normal human thoracic aorta and diseased blood
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Guangzhou Institute of Geochemistry proposes a new technology to study unculturable functional microorganisms at the single-cell level
Time of Update: 2022-04-25
microorganisms can be obtained. The isolation of functional microorganisms cannot study functional genes and metabolic pathways, which limits the application of these microorganisms with degradation functions in environmental pollution control
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NBT Dai Qionghai and others developed an artificial intelligence method for fusion analysis of cell microscopic images and genetic data—MUSE
Time of Update: 2022-04-25
> Based on the research group's accumulation in optical microscopy (Cell 2021, Nature Photonics 2019, 2020), single-cell gene analysis technology (Nature Methods 2019) and cross-application of artificial intelligence (Nature
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Learning from single cells: new techniques to unravel gene regulation
Time of Update: 2022-04-18
Analysis of single cells with EpiDamIDTo understand how PTMs affect gene expression, first authors Franka Rang and Kim de Luca devised a new method to pinpoint the location of modifications .
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Front Immunol: A single-cell resolution study of chromatin accessibility in peripheral blood
Time of Update: 2022-04-16
PBMC, peripheral blood mononuclear cells; scATAC-seq, single-cell sequencing analysis of transposase-accessible chromatin; SLE_PBMC, systemic lupus erythematosus (SLE) patient PBMC; NC_PBMC, normal human PBMC; NK cells, natural killer cells; DC , dendritic cell; TF, transcription factor; TSS, transcription start site .
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panorama of single-cell early development of rice inflorescence
Time of Update: 2022-03-08
The researchers used a single-cell sequencing system to map a dynamic panorama of early rice inflorescence development, reconstructing the developmental trajectories of rice spikelets, flowers, and various reproductive meristems .
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《Science》Single-cell spatial resolution chromatin modification map
Time of Update: 2022-03-07
Spatial CUT&Tag reveals epigenetic control of the spatial pattern of mouse cerebral cortex development and cell types determined by histone modifications .
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Stroke caused by giant cell arteritis - how much do you know about such imaging findings?
Time of Update: 2022-03-06
Figure 2 Whole body 18FDG-PET/CTAA and B showing increased grade 3 mural uptake at bilateral subclavian (A) and common carotid (B) levels (grade 3 is considered consistent with vasculitis according to a review by Nielsen et al.
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Nature Methods Publishes New Method to Improve Single-Cell RNA Sequencing Efficiency
Time of Update: 2022-03-06
"DisCo SolutionsA research team led by Deplancke has now developed a new method that allows scRNA-seq to efficiently process samples with low cell numbers .
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Alz Res Therapy: Novel Single-Cell Marker Predicts Changes in Cognitive Function
Time of Update: 2022-03-05
The significance of the study lies in its finding that at 4 years of follow-up, baseline plasma MCP-1 levels were associated with longitudinal decline in overall cognitive and representational memory performance in older adults .
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Nature reveals non-genetic determinants of malignant clone fitness at single-cell resolution
Time of Update: 2022-02-21
/> Figure 1 All in vivo experiments in this study identified pre-existing cell-intrinsic transcriptional states enriched in cancer-initiating clones. To test whether these transcriptional states were
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Peking University researchers map pan-cancer single-cell map of tumor-infiltrating T cells
Time of Update: 2022-01-27
Combining gene expression profiles and T cell receptor sequences to study the heterogeneity and dynamics of tumor-infiltrating T cells, systematically compare T cells across different cancer types .
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Single-cell structural and functional requirements for alternative splicing during hematopoietic stem cell formation
Time of Update: 2022-01-26
Here, we used single-cell full-length transcriptomic data to construct a subtype-based transcriptional profile of mouse endothelial cell-to-hematopoietic stem cell (HSC) transformation that was able to identify blood-derived signature subtypes and stage-specific AS events .
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Single-cell sequencing explores higher-order achievements in brain development
Time of Update: 2022-01-25
To understand this versatility, scientists in the Gage Crump lab created a series of atlases over time to understand the molecular decisions that CNCCs commit to forming specific tissues during zebrafish development .
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Radiology: Dual-energy CT perfusion, making imaging at the forefront of non-small cell lung cancer evaluation!
Time of Update: 2022-01-23
Several recently published studies have shown that dual-energy CT can obtain mean iodine concentration measurements throughout the tumor volume to predict the effect of tumor chemotherapy and further reflect its relationship with postoperative prognosis .
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scDIOR software breaks through the barriers of single-cell omics R/Python platform
Time of Update: 2022-01-23
The software unifies the data structure of multiple single-cell analysis tools, enables single-cell data to be quickly converted between different platforms, reduces storage and memory consumption, and significantly improves the efficiency of single-cell research .
