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Ann Transl Med: analysis of m6A-related features associated with the tumor immune microenvironment and prediction of survival in acute myeloid leukemia
Time of Update: 2022-09-30
The research team built a prognostic model using m6A-related features associated with TIME to predict the survival of AML patients.
The research team built a prognostic model using m6A-related features associated with TIME to predict the survival of AML patients.
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Ann Rheum Dis: Whole enterovirome analysis reveals link between bacteriophages and autoimmune disease
Time of Update: 2022-01-21
RESULTS: Our case-control comparison of viral abundance revealed that in the gut of patients with autoimmune diseases, particularly those with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), as a major component of healthy enteroviruses One of the crAss-like phages was significantly reduced .
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Ann Rheum Dis: Analysis of the Efficacy and Safety of Resalizumab in the Treatment of Active Psoriatic Arthritis
Time of Update: 2021-12-04
Compared with placebo, Rezalizumab treatment can significantly improve the outcome of key diseases, and it is well tolerated by PsA patients with Bio-IR and/or csDMARD-IR .
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Ann Oncol: Nutritional support for cancer patients can reduce mortality: the results of a second analysis of a prospective randomized study
Time of Update: 2021-08-02
Therefore, a foreign research team conducted a secondary analysis of a prospective randomized study, aiming to compare the effects of nutritional support (intervention group) versus control group on 30-day mortality .
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Ann Neurol-Fully automatic speech analysis, may assist Parkinson's diagnosis
Time of Update: 2021-08-02
The objectives are: (1) What are the possible differences in motor speech abnormalities among the 5 Indo-European languages, (2) Which speech patterns are most sensitive to iRBD and early PD, (3) Whether speech analysis can be within 12 months The progress of the disease was found in the follow-up evaluation .
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Ann Oncol: The efficacy of paclitaxel with or without atezolizumab in the first-line treatment
Time of Update: 2021-08-01
Among PD-L1 positive patients, the median follow-up time of atezolizumab plus paclitaxel group and placebo plus paclitaxel group were 9 months and 8.
Among PD-L1 positive patients, the median follow-up time of atezolizumab plus paclitaxel group and placebo plus paclitaxel group were 9 months and 8.
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Ann Oncol: Efficacy of atezolizumab combined with albumin-bound paclitaxel in the first-line
Time of Update: 2021-08-01
In the ITT population, atezolizumab combined with albumin-bound paclitaxel did not improve the patient's OS .
In the ITT population, atezolizumab combined with albumin-bound paclitaxel did not improve the patient's OS .
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Ann Oncol: MIRV compares the efficacy and safety of chemotherapy selected by investigators
Time of Update: 2021-07-31
Subgroup analysis Subgroup analysisIn the ITT population, the median OS between the two groups was not statistically different; among the high FRα expression population, the MIRV group had a longer median OS than the chemotherapy group (not reached vs 11.
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Ann Rheum Dis: Large-scale meta-analysis identified 11 new susceptibility loci for rheumatoid arthritis
Time of Update: 2021-04-23
8% of the heritability of SNPs in East Asian and European races respectively, and confirmed 71 known non-human leukocytes Antigen (HLA) susceptibility locus immunity Newly discovered RA susceptibility locusNewly discovered RA susceptibility locusIt can be seen that this study provides useful insights into the genetic etiology of RA and the pathogenesis of RA caused by mutations.
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Ann Rheum Dis: A meta-analysis of 208,370 East Asians identified 113 susceptible gene constellations for systemic lupus erythematosus
Time of Update: 2020-12-24
to discover new SLE gene constellations and causal variants, the study conducted the largest genome-wide meta-analysis to date in the East Asian population.
study identified 113 susceptible gene constellations for systemic lupus erythematosus and showed that large-scale genome-wide meta-analysis plays an important role in new genetic discoveries.
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Ann Rheum Dis: 2-Year Cost-Benefit Analysis of Different COBRA Enhanced Induction Remissions for Early Rheumatoid Arthritis
Time of Update: 2020-05-29
The study was designed to assess the cost-benefit of targeted treatment strategies for patients recently diagnosed with rheumatoid arthritis (RA), comparing methotrexate (MTX) and glucocorticoids (
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Ann Rheum Dis: Is rheumatoid arthritis targeted therapy really effective? Patient Queue Longitudinal Analysis (RA BIODAM)
Time of Update: 2020-05-29
The study aims to explore whether the goal of targeting ( T2T ) strategies in daily clinical practice can lead to more patients with rheumatoid arthritis ( RA ) to achieve remission goals a dis