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Integrative molecules reveal the specificity of Claudin 6 therapeutic antibodies for solid tumors
Time of Update: 2023-02-03
”9A1。 Integral Molecular, an industry leader in membrane protein antibody discovery, has released a targeting mechanism for its Claudin 6 (CLDN6) antibody ctm-76, which is being developed in collaboration with Context Therapeutics for cancer therapy.
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The Immunity TCR-Engine can be used to design synthetic TCRs with enhanced potency and specificity
Time of Update: 2023-01-06
Written by | T cells genetically modified to express TCR that recognize tumor-associated antigens are helpful for cancer immunotherapy, but usually because of the risk of cross-reactivity with off-tar
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The Immunity TCR-Engine can be used to design synthetic TCRs with enhanced potency and specificity
Time of Update: 2023-01-06
Written by | T cells genetically modified to express TCR that recognize tumor-associated antigens are helpful for cancer immunotherapy, but usually because of the risk of cross-reactivity with off-tar
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Gastroenterology: PancreaSeq, a novel NGS assay, accurately distinguishes between different types of pancreatic cysts with increased sensitivity and specificity
Time of Update: 2022-10-31
Recently, the University of Pittsburgh School of Medicine and the UPMC research team published a presentation at Gastroenterology titled "Prospective, Multi-Institutional, Real-Time Next-Generation Se
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80750-24-9 has almost the same specificity as streptomycin
Time of Update: 2022-10-01
, Ltd. shop to view other related product recommendations: Dethiobiotin 533-48-2Desthiobiotin NHS Ester 80750-24-9Desthiobiotin-PEG4-Alkyne 1802907-99-8Desthiobiotin-PEG3-Azide 1426828-06-9Desthiobiotin-PEG4-DBCO 032788-37-5Dde Biotin-PEG4-alkyne 1802908-00-4PC Biotin-PEG3-alkyne 1869922-24-6Diazo Biotin-PEG3-alkyne 1884349-58-9DADPS Biotin AlykneDde Biotin-PEG4-azide 1802907-93-2Dde Biotin-PEG4-Picolyl azide 2055048-42-3English name: Desthiobiotin NHS EsterN-Hydroxysuccinimido dethiobiotinateCAS NO:80750-24-9Molecular formula:C14H21N3O5Molecular weight:311.
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Introduction of primary antibody and secondary antibody type, specificity and selection method in experiment
Time of Update: 2022-08-30
Which class or subclass does the primary antibody belong to Fragment specificity: 3.
Which class or subclass does the primary antibody belong to Fragment specificity: 3.
Which class or subclass does the primary antibody belong to Fragment specificity: 3.
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Nature Biotechnology: a high-fidelity Cas13 system with higher specificity and better safety
Time of Update: 2022-08-19
article titleHigh-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects Figure: Design, screening, and description-engineered high-fidelity Cas13 variants A new study has revealed that through mutation, the development of high-fidelity Cas13 variants significantly reduces collateral effects .
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BJH: The specificity of the manifestations and treatment of primary immune thrombocytopenia in elderly patients
Time of Update: 2021-12-01
The purpose of a foreign study is to evaluate the clinical manifestations and management of primary ITP in very elderly patients (VEPs: age ≥ 80 years) and elderly patients (EPs: age 65-79 years), and to determine risk factors for bleeding at the initial presentation .
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Neurology: What is the clinical specificity of cerebral venous thrombosis?
Time of Update: 2021-09-29
CVT in adolescents is rare and complex, with special epidemiological characteristics , including differences in clinical manifestations and related conditions between different sexes, as well as more serious results than adults .
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C-to-G single-base editor based on deep learning algorithm to optimize sequence specificity
Time of Update: 2021-08-28
The research established the deep learning model algorithm CGBE-SMART , which can accurately predict new types Single-base editing efficiency and editing effects of OPTI-CGBEs .
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It is the first report that extracellular vesicles are rich in lncRNA-encoded polypeptides/small proteins and have certain disease specificity
Time of Update: 2021-08-26
On July 12, 2021, the team of Researcher Yang Fuquan from the Institute of Biophysics of the Chinese Academy of Sciences, the team of Academician Runsheng Chen, and the team of Professor Hongwei Zhang from Beijing Sanbo Brain Hospital published an online publication titled " Journal of Extracellular Vesicles", an international authoritative journal in the field of extracellular vesicles .
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The study reveals the developmental space-time specificity of cell esoteric variation
Time of Update: 2021-03-14
Through real-time imaging and single-cell quantitative analysis of the embryo development of the beautiful reclusive rod nematode, the team found that the variation of normal embryonic cell positioning has a high degree of certainty and consistency over time, regulated by internal and external mechanisms.
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The study found gender specificity in Alzheimer's therapy
Time of Update: 2021-03-04
many drug candidates may have different effects between different genders, we need to be extra cautious in our future clinical trial designs," said Abdelrahman, a research institute.
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Nat Commun: Molecular signs of breast cancer in Asia reveal the specificity of the disease in the population
Time of Update: 2020-12-31
molecular subtype analysis of breast cancer patients in Malaysia In this study, the researchers analyzed the number of genetic mutations, transcriptions and copies in 560 malaysian breast tumor patients, and compared the incidence of breast cancer in Asian and white women.
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An in vitro assay to study the recruitment and substrate specificity of chromatin modifying enzymes
Time of Update: 2020-12-10
In this paper, we describe a novel assay that allows sequential targeting of distinct histone modifying enzymes to immobilized nucleosomal templates using recombinant chimeric targeting molecules.
As such the assay can help to understand how a certain histone code is established and interpreted.
