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Introduction: Cell-Based Assays for High-Throughput Screening
Time of Update: 2021-02-28
Cell-based assays represent approximately half of all high-throughput screens (HTS) currently performed.
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Cell: Common fungi in the gut are like vaccines and can cause an immune response to prevent pathogenic fungal infections
Time of Update: 2021-02-28
dangerous relatives. failures in this process can make people vulnerable to deadly fungal infections. it reveals a new twist in the complex relationship between humans and their associated microbes and points the way for the development
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Mol Cell: Uncovering the special gene network of leukemia factors
Time of Update: 2021-02-28
'In this study, we designed a chemical genetic method that can shorten the analysis of transcription factors from the last few days to a few minutes,' said Dr. Kristy Stengel, a researcher at DOI:10.1016/j.molcel.2020.12.005.
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Cell Metabol: Uncover the genetic link between diabetes and fracture risk!
Time of Update: 2021-02-28
and bone density in diabetics. Now researchers have found that thousands of genetic mutations (small changes in genetic code) are directly related to an increased risk of multiple diseases, and that clarifying the role these mutations play
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Cell Metabol: Heavy! Scientists have discovered new paths that promise to attack cancer cells
Time of Update: 2021-02-28
are always looking for ways to remove cancer cells and minimize damage to other parts of the body, one possibility being to identify and target cancer cell-specific processes that, if interfered with, kill only cancer cells. process is very special
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JEM: Scientists have revealed for the first time the molecular mechanism by which intestinal corted cells regulate T-cell differentiation
Time of Update: 2021-02-28
To uncover the mystery, in this study, researchers looked for specific environmental factors at the far end of the small intestine, because endotental lymphocytes are rich in the far end of the organ, and through further study and analysis
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Int J Mol Sci: Removing microRNAs from cancer cells may be expected to reverse the progression and spread of triple negative breast cancer
Time of Update: 2021-02-28
9, 2021 // -- In a recent study published in the international journal International Journal of Molecular Sciences, scientists from the University of Westminster and others found that removing microRNAs from triple-negative breast cancer cells may
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Expression and purification of recombinant vesicular glutamate transporter VGLUT1 using PC12 cells and High Five insect cells
Time of Update: 2021-02-28
PC12 cell expressed VGLUT1 is functional but not the Baculovirus expressed protein.
The lack of functionality of the Baculovirus expressed VGLUT1 is discussed.
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The world's first CAR-T cell therapy for inert lymphoma (iNHL).
Time of Update: 2021-02-28
Pharma, a cell therapy company owned by Gilead, recently announced that it had submitted CD19 CAR-T cell therapy yescarta to the U.S. Food and Drug Administration (FDA). A supplementary biological product licensing application (sBLA
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Science Sub-Journal: Using neurons from iPS cells can be used to test treatments for Christiansen syndrome
Time of Update: 2021-02-27
study was published in the February 10, 2021 issue of the Journal of Science Translational Medicine under the title "Human neurons from Christianson syndrome ipsCs reveal mutation-specific responses to rescue strategies." images from Science Translational Medicine, 2021, doi:10.1126/scitranslmed.aaw0682.
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Science: The erythrative factor Oct4 is closely related to the expansion of the differentiation potential of cranial nerve cells
Time of Update: 2021-02-27
February 10, 2021 // --- Cell differentiation is often described as a one-way process through a series of genealogical restriction events, and as the embryo develops, the cell's differentiation potential becomes smaller and smaller, a concept
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Nat Cancer: Scientists have successfully induced internal conflicts in tumor cells with the hope of treating neuroblastoma
Time of Update: 2021-02-27
have myCN amplification in the body, such as high levels of expression, which tend to drive the out-of-control growth of tumors; a recent study published in the international journal Nature Cancer, scientists from institutions
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Mol Cell: Revealing the previously unknown dual functions of polymerases that are important
Time of Update: 2021-02-27
February 15, 2021 // -- As the deadliest form of DNA damage, double-stranded fractures of DNA must be repaired to prevent cell death; Scientists aim to identify new ways to block cancer cells' ability to repair DNA ruptures, and a new study has
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Cell Rep: Uncover the molecular pathogenes of inhibited T-cells that promote the development of chronic immune diseases in the body
Time of Update: 2021-02-27
a special technique to expose genetically modified mice to different doses of antibiotic strong mycomycin, which controls the synthesis of antigens through drinking water, and a different number of antigens that can be presented to T-cells in these animal
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Cell: Tumor immunotherapy can be used to treat malignant brain cancer
Time of Update: 2021-02-27
February 15, 2021 /--- -- Scientists have identified a new target for a potentially malignant brain tumor immunotherapy, according to a recent paper published in the journal Cell.
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Want to live to be 120? Stem cell technology can help you dream
Time of Update: 2021-02-27
In recent years, stem cells and regenerative medicine have become a hot topic in the field of health, and these new technologies can not only treat diseases, but also be used to fight aging.
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First-line treatment for renal cell carcinoma: Hundreds of meters /Exelixis "Immune and Targeting
Time of Update: 2021-02-27
Cancer Symposium (ASCO-GU 2021) on March 13, confirm the clinical significance of the first-line treatment of advanced renal cell carcinoma (R) CC) compared to the first-line standard care drug Suttent (Sotan, generic name: sunitinib, shonithini
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Phosphopeptide mapping of proteins ectopically expressed in tissue culture cell lines
Time of Update: 2021-02-27
We generated phosphopeptide maps of the phosphorylated HAND1 using the methods described below and linked these modifications to changes in HAND1 biological function.
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Front Neurosci: Star brain cells are associated with stuttering
Time of Update: 2021-02-27
mechanism for the role of ketones in stuttering appears to involve in part an increase in the metabolism or activity of star-shaped glial cells in the syroids.
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Nature: In the early stages of vertebrate embryos, endocysts devour to quickly remove defective cells
Time of Update: 2021-02-27
this is the first time that this biological process, called epithelial phagocytosis, has been shown to remove defective cells from newly formed vertebrate embryos.
