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Frontier | Innovative therapy reverses the symptoms of Alzheimer's disease in animals and stimulates the ability of cells to "clean up garbage"
Time of Update: 2021-05-09
The researchers further observed the single-cell RNA sequencing data of brain neurons in patients with Alzheimer's disease and control healthy individuals.
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FDA update | Accelerated approval of loncastuximab tesirine-lpyl for the treatment of patients with large B-cell lymphoma
Time of Update: 2021-05-09
15 mg/kg every 3 weeks; in the subsequent treatment cycles, patients received loncastuximab tesirine-lpyl 0.
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Science latest: single-cell interaction sequencing technology reveals the communication code between glial cells
Time of Update: 2021-05-09
In summary, this article has discovered two signaling molecular pathways that "talk" between microglia and astrocytes through the development of a new cell-interacting single-cell sequencing technology RABID-seq: EphB3-Ephrin-B3 and Sema4D-PlexinB2.
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Professor Yi Shuhua: Research on treatment and prognosis models go hand in hand, and diagnosis and treatment of mantle cell lymphoma is poised to take off
Time of Update: 2021-05-09
, BCL-2 inhibitors, immunomodulators lenalidomide, and chimeric antigen receptor T cells (CAR-T). Among them, CAR-T therapy can be described as a revolutionary treatment for relapsed and refractory mantle cell
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Cell|Systematic exploration of the role of molecular chaperone autophagy in neurodegenerative diseases
Time of Update: 2021-05-09
After molecular chaperone autophagy is inhibited, protein degradation is abnormal and neuronal function is affected.
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Cell blockbuster: Enhance neuronal autophagy, clear brain toxic proteins, reverse Alzheimer’s disease, and anti-aging
Time of Update: 2021-05-09
The research team has developed an experimental drug that can clear the tau protein by activating chaperone-mediated autophagy (CMA) in brain neurons and reverse key symptoms in a mouse model of Alzheimer's disease.
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Cell Stem Cell | Anti-aging as early as possible—Mature brains have already appeared with molecular aging characteristics of neural stem cells
Time of Update: 2021-05-09
In summary, this study showed that short-term and long-term NSCs exhibit asynchronous depletion through clone tracing, and single-cell transcriptome analysis of deep neural stem cells in the resting phase revealed molecular aging characteristics in mature brains.
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Nat Comm | Wu Qingfeng's team reveals that hypothalamic extension cells have the duality of angels and demons
Time of Update: 2021-05-09
of Sciences published an online research paper on Nature Communications entitled: Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice. The study found that the Rax
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Sub-Journal of Nature: Gu Zhen's team developed a "cell warehouse" to help CAR-T treat solid tumors
Time of Update: 2021-05-09
▎The editor of WuXi AppTec’s content team today published an interesting study in the sub-issue of Nature
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Recombinant new coronavirus vaccine (CHO cells) is approved for emergency use | Transformation Highlights
Time of Update: 2021-05-09
On March 10, 2021, the recombinant novel coronavirus vaccine (CHO cell) jointly developed by the Institute of Microbiology of the Chinese Academy of Sciences and Anhui Zhifeilongkoma Biopharmaceutical Co.
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Science Sub-Journal: iPS Stem Cell Therapy Successfully Promotes the Recovery of Stroke and Dementia
Time of Update: 2021-05-09
progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents in the Science Translational Medicine journal. Research papers. The research team used artificially induced
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Cell Journal: Wang Rongfu's team confirmed that a single intestinal strain can inhibit colon cancer
Time of Update: 2021-05-09
2020 hot articles selection 1. Cup! A full paper cup of hot coffee, full of plastic particles. . . 2. Scientists from the United States, Britain and Australia “Natural Medicine” further prove
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Innovative therapy reverses the symptoms of Alzheimer's disease in animals and stimulates cells to "clean up garbage"
Time of Update: 2021-05-09
"On April 22, researchers at the Albert Einstein College of Medicine in New York, the United States, announced the design of an experimental drug designed to stimulate a special cell "garbage cleanup" mechanism, which can be used in animal models.
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2021Q1 Cell Therapy Inventory: Global financing totals over US$3.7 billion, 8 companies IPO listing
Time of Update: 2021-05-09
8 billion US dollars to use Artiva's spot-type allogeneic NK cell manufacturing platform And proprietary CAR-NK technology to develop new CAR-NK cell therapy for solid tumor-related antigens.
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; the first-line treatment of esophageal squamous cell carcinoma with teriprizumab in Phase III study is successful
Time of Update: 2021-05-09
information" in the tumor circle! (If you need the original text of the literature, you can add to the editor WeChat yxj_oncology to obtain) Key points remind Liver Cancer: A+T regimen can change the treatment practice of Chinese patients
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Protein & Cell | Yang Jing's team reveals a new immunomodulatory effect on degenerative diseases of the enteric nervous system
Time of Update: 2021-05-09
is an unsolved question in the field. In fact, it has never been reported whether axonal degeneration may play a beneficial role under certain disease conditions. The answer
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Experts comment on Cell Stem Cell | Wu Qingfeng's team discovers a new law of the origin of neuronal diversity
Time of Update: 2021-05-09
| The nervous system is one of the most complex and important organs of the human body. An in-depth understanding of neurodevelopment plays an important role in neuroscience research and regenerative medicine
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Cell | Dopamine's "wave-like dynamics", revealing the timing and conditioning mechanism of reward behavior in the brain
Time of Update: 2021-05-09
According to the reward prediction error (RPE) hypothesis proposed by Schultz in 1997 [1], the dopamine signal reflects the deviation between the expected reward and the actual reward in reinforcement learning (RL).
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Effectively reduce cell damage in the hypoperfusion zone, this medicine protects the brain tissue!
Time of Update: 2021-05-09
was obtained from the third set of experimental results, and the units of tissue concentration and plasma concentration were ng/g and ng/ml, respectively. Nicardipine can effectively reduce the cell damage
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An overview of the article: 2021 CSCO Small Cell Lung Cancer Guidelines Update Key Points
Time of Update: 2021-05-09
"The ALTER1202 study update at the ASCO conference in 2020 shows that Anlotinib can significantly improve the PFS and OS of patients with relapsed SCLC within 3 months of second-line treatment.
