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New review: Stem cells promise to be a new generation of treatments for neurological disorders
Time of Update: 2021-02-24
Progenitor cell therapy for acquired pediatric nervous system injury: Traumatic brain injury and acquired sensorineural hearing loss.
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Generation of Murine Bone-Marrow-Derived Dendritic Cells
Time of Update: 2021-02-18
Derived from stem cells in the bone marrow, DC migrate to the tissues where they become “sentinels” of the immune system.
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Dendritic Cell Generation from Highly Purified CD14+Monocytes
Time of Update: 2021-02-15
Dendritic cells (DC) play a pivotal role in the function of the immune system, for they are the primary antigen-presenting cells (APC) in the activation of naive T-lymphocyte responses ( 1 ).
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Generation of Langerhans Cell-Like Dendritic Cells from Murine Fetal Skin
Time of Update: 2021-02-12
The dendritic cell (DC) lineage is comprised of bone marrow-derived cells that are present in small numbers in nonlymphoid as well as lymphoid tissues ( 1 ). Nonlymphoid DC, such as epidermal Langerhans cells (LC), display
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Generation of Blood-Derived Human Dendritic Cells for Antitumor Immunotherapy
Time of Update: 2021-01-31
Dendritic cells (DC) are a family of bone-marrow-derived professional antigen presenting cells (APC) with sparse, but wide, tissue distribution ( 1 ).
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An analysis of the general situation and development trend of the cell therapy drug industry
Time of Update: 2021-01-30
Table 1 Details of registered stem cell drug clinical trials in China Data source: CDE, Firestone Creation and Finishing (ii) The global market for cell therapy products is one of the fastest growing sub-sectors of the biopharmaceutical market.
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Affinity Isolation of Antigen-Specific Circulating B Cells for Generation of Phage Display-Derived Human Monoclonal Antibodies
Time of Update: 2021-01-27
A method is described for affinity isolation of antigen-specific circulating B cells of interest for subsequent generation of immune antibody phage display libraries.
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Generation of Envelope-Modified Baculoviruses for Gene Delivery Into Mammalian Cells
Time of Update: 2021-01-27
Methods of generating a recombinant baculovirus vector with a modified envelope and its amplification and purification, including technical scale production, are discussed.
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Mercadon locks out TRACEr technology to develop next-generation T-cell therapy
Time of Update: 2021-01-12
preclinical studies have shown that TRACTr drugs can achieve high safety multiples and have anti-tumor properties comparable to standard TCE, while preventing cytokine release, healthy tissue toxicity, and systemic immunoactivation.
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Mercadon locks out TRACEr technology to develop next-generation T-cell therapy
Time of Update: 2021-01-04
to the development of TCE therapy. The first generation of TCE triggers a systemic immune response that attacks not only tumors, but also healthy tissue, and the toxicity that can be life-threatening; not only limits the development of TCE
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Eicosanoids: Generation and Detection in Mammalian Cells
Time of Update: 2020-12-02
Recent advances in their detection and analysis using mass spectrometry have made the study of these molecules more accessible to the research community in general.
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Cancer Cell overview article interpretation! How to develop a new generation of cancer therapy for CAR-T cell engineering modification?
Time of Update: 2020-11-28
of step cell therapy, but achieving a broader therapeutic application of CAR-T cells requires a multi-layered engineering approach Improving the efficacy and safety of treatment, especially since the biological complexity of the tumor microenvironment (TME
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Development of a new protocol for 2-day generation of mature dendritic cells from human monocytes
Time of Update: 2020-11-26
We developed a new 2-day protocol for the generation of dendritic cells (DCs) from human monocytes in vitro .
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OrR reached 86% of patients with specific non-small cell lung cancer with positive clinical results for next-generation precision therapy.
Time of Update: 2020-10-01
, for example, Roche's Rozlytrek, which targets THES1 and NTRK gene fusion, received FDA accelerated approval last year to treat NSCLC patients with ROS1 gene mutations and solid tumor patients with NTRK fusion.
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New refrigeration coatings improve solar cell efficiency.
Time of Update: 2020-09-15
or electronic devices, said Zhu Linxiao, the first author of the paper and part of Fan's team. For example, the car in the sun for a while will be very hot, which brings some safety problems, but also the next time the car's air conditioning needs
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What is the general situation of clinical research on stem cell treatment of freezing disease?
Time of Update: 2020-09-09
, for example, phase I/IIa clinical trials of interstitating stem cells injected into patients have shown that this therapy provides potential neurotrophic support for motor neurons and demonstrates the safety and effectiveness of treatment.
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First-line treatment of non-small cell lung cancer Pfizer's third generation APK inhibitors reached the stage 3 clinical endpoint.
Time of Update: 2020-09-06
2018, the FDA accelerated approval of Lorbrena to treat patients treated with ALC-positive metastasis NSCLC.
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Human stem cells have created the first brain-like organ with myelin-generating function.
Time of Update: 2020-08-09
A U.S. team of researchers has developed a new method to create the first brain-like organ with myelin-generating function using human stem cells, according to a study published online in the journal Nature Methods on Wednesday.
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How far are we from a new generation of stem cell therapy?
Time of Update: 2020-08-03
, stem cell therapy remains a major focus, with a proliferation of new pharmaceutical companies such as Bayer, Novo Nordisk and Takeda, which are also involved in the development and clinical application of the technology.
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Nature Cell Biology: The Jiang Hao team revealed that AKAP95 can regulate gene splicing and tumor generation through phase separation.
Time of Update: 2020-07-30
, Biophysical Propertyies of AKAP95 Protein Condensates Regulate splicing and tumorigenesis, revealing that the nucleus protein KAP95 regulates gene spruns and tumor generation through liquid phase separation within the range of appropriate condensed body
