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Gene Therapy: Methods and Application
Time of Update: 2021-03-06
, to treat or prevent a disease1 – 3 ). The process involves a group of technologies that enable the intentional transfer of specific exogenous genetic information into cells and the application of these technologies for pharmaceutical
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Bioluminescent Imaging of MAPK Function with Intein-Mediated Reporter Gene Assay
Time of Update: 2021-03-06
Upon stimulation with EGF, the interaction between Ras and Raf-1 triggers folding of the DnaEs, thereby inducing protein splicing to form mLexA–VP16AD fusion protein and transcription of a reporter gene, firefly luciferase.
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Roche has signed a contract with Dyno Therapeutics, a gene therapy vector
Time of Update: 2021-03-06
signed a partnership agreement with Dyno Therapeutics to develop adenovirus (AAV) vectors for gene therapy for central nervous system (CNS) disease and liver targeted therapy. Under the terms of the agreement
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The new gene tool promises to solve the mystery of marine microbes
Time of Update: 2021-03-06
In a series of studies of animals, plants, yeasts and bacteria, scientists found important clues as they modified the cell genes of organisms.
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Scientists have discovered important genes that increase the number and yield of rice
Time of Update: 2021-03-06
the 1950s and 1960s, breeders used "dwarf genes" to improve crop strains such as rice and wheat to cultivate high-yielding species, known as the "Green Revolution".
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Dynamic Monitoring of Cellular Remodeling Induced by the Transforming Growth Factor-1
Time of Update: 2021-03-06
This novel application of such approach demonstrated a great potential of the impedance-based system for noninvasive and real-time monitoring of cellular fate.
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The mechanism of regulating yield of super rice grain wide grain heavy gene is revealed
Time of Update: 2021-03-06
The study cloned a rice grain wide grain heavy QTL/gene and carried out functional analysis, which laid the foundation for the clarification of the genetic control mechanism and high-yield molecular breeding of rice granules.
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Chinese scientists have discovered a stable and high-yield gene for hybrid rice
Time of Update: 2021-03-06
Xinhua News Agency, Hangzhou, March 28 (Xinhua) -- A team led by Qian Qian of the China Rice Research Institute , Xiong Guosheng of the Shenzhen Agricultural Genomics Research Institute and Li Jiayang of the China Institute
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factors of neurodevelopment and their mechanism of action
Time of Update: 2021-03-05
in this study, Yang Chonglin Research Group and Guo Weixiang Research Group worked together to find that WDR91 was recruited into the internal swallowing body by combining its C-end with the active form of the small GTP enzyme Rab7.
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-making of gene sequences on chromosomes
Time of Update: 2021-03-05
Wenfeng Research Group of the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences speculated that genetic interoperability networks were an important factor affecting gene sequentiality, based on evolutionary theoretical models.
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Studies have revealed the existence of a wide range of monoethonal gene expression in plants
Time of Update: 2021-03-05
The Qian Wenfeng and Wang Xiujie research group used single nucleotide polymorphisms between the 93-11 and Nipponbare subseeds to estimate the expression of two allied genes in F1 cells.
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Chinese and foreign scientists have successfully cloned the wheat male sterility gene Ms1
Time of Update: 2021-03-05
Therefore, the cloning of wheat recessive male infertility mutant gene is very important to the creation of large-scale wheat hybridization system.
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Genes put colorful clothes on parrots
Time of Update: 2021-03-05
Now, researchers have reported a study of tiger-skin parrots, citing new evidence to explain how the birds produce their distinctive yellow, blue and green feathers.
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PCR Cloning of Human Immunoglobulin Genes
Time of Update: 2021-03-05
This is best accomplished using the polymerase chain reaction ( PCR ).
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Why is Super Rice Super? This gene is at work
Time of Update: 2021-03-05
BEIJING, March 23 (Xinhua Yan Jian) According to the latest news from China Agriculture , the Qian team of China Rice Research Institute, in cooperation with China Agriculture Shenzhen Agricultural Genome Research Institute
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Large-scale deciphering of human tissue gene activity
Time of Update: 2021-03-05
are expressed. However, there is still limited research on differences in gene regulation and gene expression between different human tissues and individuals. The Genotype-Tissue Expression (GTEx) Research Alliance collected and studied more
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The gene-editing CRISPR-Cas9 study yielded new results
Time of Update: 2021-03-05
The results analyze the ACTIVE structure of DNA shearing in CRISPR-Cas9 by using the three-dimensional reconstruction method of single particles of cryoelectric mirrors, and important progress has been made in the study of DNA shear mechanism of CRISPR-Cas9.
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The FDA stopped Voyager gene therapy to treat Huntington's disease
Time of Update: 2021-03-05
Later on Tuesday, Cambridge, Massachusetts-based Voyager announced that the FDA had issued a clinical stay on its application for a new drug (IND) for the company's gene therapy VY-HTT01 for huntington's disease.
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Lilly's application for a new drug to develop RNAi gene therapy is authorized
Time of Update: 2021-03-05
November 16, RNA Interference (RNAi) gene therapy drug developer Dicerna Pharmaceuticals, Inc., announced that the FDA has now authorized a new drug application (IND) code-named LY3561774, the first clinical phase drug candidate for Dierna in partnership with Lilly.
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Scientists at the Chinese Academy of Sciences have bred gene-edited lean pigs
Time of Update: 2021-03-05
million years ago. To this end, they used gene-editing tools to integrate the UDP1 gene into the genomes of fibroblasts in pig fetuses, crafting more than 2,500 cloned pig embryos, which were then injected into 13 surrogate sows, three of which
