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JCEM: Racial differences in the association of C-reactive protein with incidence of type 2 diabetes
Time of Update: 2022-03-04
Inflammation was associated with an increased risk of diabetes in both men and women , and black adults had significantly elevated inflammatory biomarkers, including C-reactive protein, compared with white adults .
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Alz Res Therapy: a new type of cerebrospinal fluid protein that can effectively distinguish dementia from cognitive decline
Time of Update: 2021-11-11
Healthy control group, SCD, mild cognitive impairment (MCI), AD and non-AD dementia patients (cohort 2) .
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CAR-T cells targeting intracellular proteins are expected to greatly expand the types of cancers that can be treated
Time of Update: 2021-11-11
Moreover, further studies have shown that even if the PHOX2B polypeptide is presented to the cell surface by different MHC types, this CAR-T cell therapy can recognize it .
bio/myrio-therapeutics-data-published-in-nature-unlocking-new- targets-for-antibody-based-therapies/[2] CHOP researchers develop a new class of CAR-T cells that target previously untargetable cancer drivers.
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"Diabetologia" Intake of new whey protein before meals can improve blood sugar control in patients with type 2 diabetes
Time of Update: 2021-10-10
Whey protein microgel can reduce the spike in blood sugar after a meal and improve the body's insulin response (clearing glucose in the blood) .
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Lancet Diabetes Endo: The effect of dapagliflozin on urine protein in chronic kidney disease patients with type 2 diabetes
Time of Update: 2021-10-10
diabetesThe DAPA-CKD study is a multi-center, double-blind, placebo-controlled randomized trial conducted in 386 locations in 21 countries to evaluate the effect of dapagliflozin on proteinuria in patients with chronic kidney disease with type 2 diabetes Impact .
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Protein-regulated kainate-type glutamate receptor structure revealed
Time of Update: 2021-09-28
Photo courtesy of Nanjing UniversityThe structure of the desensitized GluK2-NETO2 complex .
In the paper of "Cryo-electron Microscope Structure of Receptors", the research team revealed the structural basis of NETO protein regulating the function of kainate-type glutamate receptors in the brain .
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Injection of this small protein can protect type 1 diabetic cells
Time of Update: 2021-08-27
"The mitochondrial genome encodes previously unknown genes that produce small proteins with multiple physiological roles, including aging, exercise, metabolism, and immunity," Lee said .
Mitochondrial-encoded MOTS-c prevents pancreatic islet destruction in autoimmune diabetes .
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A major discovery: all cancer types can be divided into two types according to whether YAP protein is expressed or not
Time of Update: 2021-08-07
Some cancers such as prostate cancer and lung cancer can also transition from YAPon state to YAPoff state to resist treatment .
In general, this study shows that all cancers can be divided into two categories based on the presence or absence of YAP protein-YAPon cancer and YAPoff cancer .
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Clinical Nutrition: Habitual intake of soy protein and isoflavones can reduce the risk of type 2 diabetes in women
Time of Update: 2021-03-21
Therefore, the researchers conducted a prospective study on the relationship between dietary soy protein and isoflavone intake and the risk of type 2 diabetes among Korean adults ≥40 years of age.
The association between soy protein and isoflavone intake is very obvious in women, but not in men.
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Substrate Analysis of Arabidopsis PP2C-Type Protein Phosphatases
Time of Update: 2021-03-15
Studies of PP2C activities can be performed in vitro using recombinant proteins.
The members of the PP2C phosphatase family demonstrated specificity toward the substrate already in vitro, supporting the notion that protein phosphatases are specific enzymes.
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Capillary Electrophoresis with Laser-Induced Fluorescence Detection of Proteins from Two Types of Complex Sample Matrices: Food and Biological Fluids
Time of Update: 2021-03-05
Sample preparation and laser-induced fluorescence detection are two key steps of the analytical methodology to determine bycapillary electrophoresis low concentrations of proteins in complex sample m
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A new type of protein that provides nutritional and functional benefits
Time of Update: 2021-02-04
The growing demand for protein opens up new product opportunities for food processors.
This protein not only meets basic nutritional needs, but also becomes a source of functional additives in value-added processed foods.
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Sequence Analysis of the Variable Number Tandem Repeat in Staphylococcus aureus Protein A Gene: spa Typing
Time of Update: 2021-02-01
VNTR analysis is currently widely used to sub-speciate many bacterial, fungal, and viral pathogens and has facilitated a number of molecular epidemiology studies.
In this chapter, we focus onspa typing which is based on sequence analysis of VNTRs in the polymorphic X region of theStaphylococcus aureus protein A geneStaphylococcus aureus .
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STTT: The new coronavirus M protein inhibits the activation of type I and III interferon to achieve immune escape
Time of Update: 2021-01-12
The new coronavirus (SARS-CoV-2) is a single-stranded RNA virus that can spread across species and infect humans. The new crown pneumonia (COVID-19) caused by SARS-CoV-2 infection has become a global
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JEM: Targeting special T-cell proteins may inhibit the development of type 1 diabetes
Time of Update: 2020-12-27
DECEMBER 14, 2020 // -- In a recent study published in the international journal Journal of Laboratory Medicine, scientists from the University of Utah School of Medicine and others identified a new therapeutic target or could help treat type 1 diabetes patients by inhibiting a protein called OCA-B or protecting mice from the activity of β cells that destroy insulin-producing cells in the pancreas.
