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Clin Cancer Res: DNA methyl transferase inhibitor Guadecitabine combined with cisplatin and giscitabine to treat solid malignancies

 Time of Update: 2021-02-25

, guadecitabine combined with Giscitabine and Shunplain RP2D is 20 mg/m2 for 1st to 5th days and requires G-CSF to prevent bone marrow inhibition.
JCO: The treatment of rhonamide combined with R-CHOP can prolong the survival of patients with untreated diffuse large B-cell lymphoma

 Time of Update: 2021-02-25

For untreated patients with diffuse large B-cell lymphoma (DLBCL) (including COO and ABC-DLBCL subtypes), the Synadamic Unilidoxi monoantigen-cyclophosphamide-dorobi-star-changchun-neo-alkali-pernisson (R-CHOP) program (R2CHOP) can extend its lifetime.
ASCO GU 2021: The efficacy of the combined treatment of metastatic renal cell carcinoma with Navuliyu monoanti- and Ipi-anti-anti-drugs

 Time of Update: 2021-02-25

At present, the combination of Navuliyu monoanti-Ipi monoanti and vascular endodermal growth factor (VEGF) inhibitor immunotherapy is a first-line treatment for metastatic renal cell carcinoma (mRCC).
Clin Cancer Res: Pym single-drug treatment PD-L1 combined positive score≥10 efficacy of gastric/gastroesophageal junction cancer

 Time of Update: 2021-02-25

, respectively. to better describe the specificity of CPS as a clinical prognostic predictor, the researchers further analyzed the efficacy of Pym monoantia in patients who ≥ CPS≥10. this analysis includes KEYNOTE-059 queue 1 (Pim monoantial, n
JAMA Neurol: Pernisson Shock Therapy combined with a rapid reduction program to treat moderate to severe muscle weakness

 Time of Update: 2021-02-24

and there was no recurrence at 15 months. 117 patients were involved in the study, including 58 in the slow-down group, 59 in the fast-reducing group and 62 in men, with an average age of 65. group of 23 reached the main finish line, while the slow-down
research progress in food safety testing based on cellulose-based multi-functional substrate combined with SERS intelligent sensing

 Time of Update: 2021-02-24

in food safety testing of the latest research progress days ago, South China University of Technology Sun Dawen in the food field of the world's top journals (TOP1) Trends in Food Science and Technology (IF s 11.077) published online
Somaglutide combined with cilofexo/firsocostat treatment NASH II with positive results

 Time of Update: 2021-02-24

The study reached the main clinical endpoint, and patients with NASH with mild and moderate liver fibrosis were well-resistant to all treatment options. most common adverse events (AEs) are gastrointestinal reactions. itching symptoms
AZ's Breztri scored in the COPD trial, adding a place to GSK's triple-combined battle

 Time of Update: 2021-02-24

Related: analysis: AstraZeneta's Fasenra offers two-year benefits to people with severe asthma Meanwhile, AstraZeneta can rest assured that it will use other breathing drugs to boost GlaxoSmithKline while waiting for the triple-combination to catch up.
JCO: Chemotherapy combined with primary tumor removal does not improve the efficacy of patients with advanced colorectal cancer

 Time of Update: 2021-02-24

Since PTR's follow-up chemotherapy did not show a survival benefit over chemotherapy alone, PTR should no longer be considered the standard of treatment for CRC patients with asymptomatic primary tumors and synchronous non-removable metastasis.
Xinda Bio and Sanoki have reached a clinical partnership to develop Xindili monoantigen combination therapy

 Time of Update: 2021-02-24

Bioinnovatable Oncology Drug Dabershu® (recombinant all-human source anti-PD-1 monoclonal antibody, English trademark: Tyvyt®, chemical generic name: Xindili monoanti-injection) joint clinical development of drugs, the proposed development of the adaptive
The disease control rate of 90% mRNA cancer vaccine/Keytruda combination had positive early clinical results

 Time of Update: 2021-02-24

mRNA-4157 was used in a phase 1 clinical trial to treat HPV-negative head and neck squamous cell carcinoma (HNSCC) patients with a total remission rate (ORR) of 50% (ORR) and a 9.8-month medium progressive survival (mPFS).
ASCO GU 2021: Nivolumab combined with Cabozantinib and Schoinidinib in late-stage renal cell carcinoma (CheckMate 9ER study)

 Time of Update: 2021-02-24

the authors concluded that, in addition to previously provided data showing the advantages of progress-free and overall lifetime, patients treated with nivolumab and Cabozantinib had statistically significant HRQoL benefits compared to patients treated with schoinib.
J Clin Oncol: Eprenetapopt combined with Aza cytosine to treat TP53 mutant MDS and AML

 Time of Update: 2021-02-24

Regardless of the treatment, the prognostics of TP53 mutation (TP53m) bone marrow prognostic abnormal syndrome (MDS) and acute myeloid leukemia (AML) were very poor, with only 40% remission rate (full remission rate of 20%) for Azatide (AZA
The study found four major combinations that increased the risk of death in new crown patients

 Time of Update: 2021-02-23

the condition in patients with neo-coronary disease, but the extent to which a particular co-ed affects neo-coronary disease is unclear. "This global study covers all the combinations associated with the worsening death of the new coronary disease
with the new auxiliary drug Narvon anti-monodrive therapy or combined Ipi monotherapy

 Time of Update: 2021-02-23

memory T cells. increase in the number of gastroenteroccal genus intestinal tumors and Akkermansia spp, which are associated with dual-therapy MPR. In summary, the results of this study show that the treatment based on the new auxiliary drug
Toripalimab is a combination of chemotherapy to treat nasopharyngeal cancer, and China's State Drug

 Time of Update: 2021-02-23

Chinese pharmaceutical company Junshi Bio recently announced that China's State Drug Administration (NMPA) has accepted a new supplemental drug application for the first-line treatment of relapsed or metastatic nasopharyngeal cancer with Toripalimab combined chemotherapy.
An Approach Combining Rapid cDNA Amplification and Chemical Synthesis for the Identification of Novel, Cathelicidin-Derived, Antimicrobial Peptides

 Time of Update: 2021-02-21

Host defense in mammals involves a cooperative effort by a variety of antimicrobial peptides ( 1 ), which are produced by both phagocyte precursors and some epithelia. They are called on to combat invading pathogens at sites
Pomegranate extract and chrysanthemum sugar may be a high-quality cholesterol-lowering combination

 Time of Update: 2021-02-17

PomX alone increased gene expression of two key regulatory factors in the bile acid synthesis pathway, reducing hepatic triglyceride levels, while chrysanthemum powder had no significant effect on liver or serum triglyceride levels.
Cargies launches a new sweetener that combines stevia, honey and sugar.

 Time of Update: 2021-02-17

cargy company is about to launch Truvia Nectar , a brand new liquid sweetener, sold in plastic squeeze bottles.
Fda approves Piqray pills in combination with fullvestrant therapy

 Time of Update: 2021-02-16

, and clinicians were advised to monitor these conditions during treatment. piqray was approved by Novaral, while thetheerascreen PIK3CA RGQ PCR kit was approved for QIAGEN Manchester Ltd. (Drug Information Network)

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