: one symbol: p<0. 05; two symbols: p<0. 01; saline: n=6/prenatal treatment/stress condition/time point; injected adjuvant: n=14/antenatal treatment/stress condition/point in time .
Evidence that vitamin K is beneficial to the rat brain
Time of Update: 2022-04-16
In a new study in rats, scientists report evidence that vitamin K can help prevent cognitive decline associated with Alzheimer's and other forms of dementia .
Uganda plans to develop 5 food standards
Time of Update: 2022-03-03
On February 4, 2022, the Uganda National Bureau of Standards issued a consultation
Empowering new drug discovery researchers to develop the first rat model that fully mimics human AD
Time of Update: 2022-02-26
Through a head-to-head comparison study with AppNL-GF mice, Professor Lu Bai's team pointed out that from the persistent death of nerve cells and the resulting brain atrophy, as well as tau protein pathology, another key feature of Alzheimer's disease, etc.
Latest research: Naked mole rats don’t seem to age but age at the molecular level
Time of Update: 2022-01-09
Researchers use epigenetic changes to measure, I found a rodent with an extremely long life-naked mole rats that don't seem to age on the outside, but do age at the molecular level .
Nature Aging: Naked mole rats reveal their age through epigenetics
Time of Update: 2022-01-08
They say that using epigenetic clocks can not only estimate the age of wild naked mole rats, but also help study their potential as model organisms for aging, longevity, and disease suppression .
that the envelope and fine structure of sound have different binaural processing modes in the rat’s auditory midbrain
Time of Update: 2021-12-27
Different binaural processing of the envelope component and the temporal fine structure component of a narrowband noise in rat inferior colliculus.
The insular cortex balances the rats’ psychological and physical responses to fear|Science Weekly Selection
Time of Update: 2021-12-06
Previous studies have shown that the insular cortex (InsCtx) plays a role in processing body signals and possibly in maintaining and subtracting fear .
Cell Res | Tsinghua University Lu Bai/Guo Wei created a rat model of Alzheimer's disease to better simulate the symptoms of human Alzheimer's disease
Time of Update: 2021-12-06
On November 17, 2021, Tsinghua University Lu Bai and Guo Wei jointly published a research paper entitled "An App knock-in rat model for Alzheimer's disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments" in Cell Research.
To assist in the development of new drugs, the Tsinghua Lubai team developed the first rat model that fully simulates human Alzheimer's disease
Time of Update: 2021-12-06
Through a head-to-head comparison study with AppNL-GF mice, Professor Lu Bai’s team pointed out that from the persistent death of nerve cells and the resulting brain atrophy, as well as another key feature of Alzheimer’s disease, tau protein pathology, etc.
Nature: Lu Bai's team at Tsinghua University has developed the world's first rat model that fully simulates human Alzheimer's disease
Time of Update: 2021-12-04
>more than 200 AD animal models, but these models either have no nerve cell death
JE: Study on the mechanism of Fuzheng Xiaozheng Recipe in alleviating liver cancer in rats
Time of Update: 2021-12-03
IL-10, IFN-γ)In summary, the results of this study suggest that Fuzheng Xiaozheng Recipe has a significant alleviating effect on hepatocellular carcinoma, and may inhibit the progression of liver cancer by regulating lipid-related metabolism and enhancing anti-inflammatory ability .
J Cell Physiol: Dapagliflozin improves pancreatic injury in obese rats and activates renal autophagy by modulating AMPK/mTOR signaling pathway
Time of Update: 2021-11-12
To explore the effects of dapagliflozin on insulin resistance, renal autophagy, pancreatic oxidative stress, endoplasmic reticulum stress, inflammation and cell apoptosis in obese rats induced by high-fat diet .
Nature Immunology, Zhao Yang and others found that blind mole rats use "junk DNA" to fight cancer
Time of Update: 2021-11-03
Responsible editor | Xi's selfish genetic elements were once thought to be mere parasites of the genome . The blind mole rat
of the distribution area of China's main domestic pest-Yellow-breasted rat to the north
Time of Update: 2021-10-22
of the main domestic pest rattus tanezumi (Rattus tanezumi) in China's rapid expansion to high latitudes and high altitudes . > Yellow-breasted rat is one of the most widely
Neural Regen Res: Electroacupuncture can affect the pain sensation of nicotine-dependent hyperalgesia model rats
Time of Update: 2021-10-20
with morphine, acupuncture is more effective, faster and better tolerated . Studies have shown that one way to avoid chronic opioid dependence is to use
OMCL: The renal protection induced by aerobic exercise in obese Zucker rats depends on the bioavailability of nitric oxide
Time of Update: 2021-10-20
of renal vasoactive peptides after receiving L-NAME (N(omega)-nitro-l-arginine methyl ester) . >With l-arginine as a substrate, NO synthase (NOS) activity increases