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ase-linked immunoanalytase analysis of BK) enzyme-linked immunoanalytases in rats
Sanno Bio Iteba peptide injection was approved for production and regarded as the first in China
Time of Update: 2020-12-26
elevation myocardial infarction), with rapid effect, strong anti-platelet effect, drug effect reversible and so on. figure 1: 2015-2019 Sales of end-to-ethyba peptide injections in China's public medical institutions (units: 100 million yuan) Source
Gastroenterology: Analysis of the efficacy and safety of Tadhipitant, a neuro-peptide-1 inhibitor, in patients with diabetes and idynogenic gastric palsy
Time of Update: 2020-12-24
Tradipitant is an effective NK1R selective inhibitor that can be used to treat gastric palsy by inhibiting the brain's nausea and vomiting center and stimulating smooth muscle peristaltic movements in the intestines.
Stabilization of Collagen-Model, Triple-Helical Peptides for In Vitro and In Vivo Applications
Time of Update: 2020-12-24
We presently describe approaches by which triple-helical structure can be modulated for use underphysiological or near-physiological conditions.
Quantitative Analysis of Peptide and Protein Changes in Ischemic Hippocampal Tissue by HPLC
Time of Update: 2020-12-24
Histologically, global cerebral ischemia results in the selective, delayed neurodegeneration of hippocampal CA1 pyramidal neurons in humans and rats ( 1 , 3 ).
In Situ Chemical Modification of Peptide Microarrays: Application to the Study of the Antibody Responses to Methylated Antigens
Time of Update: 2020-12-21
The accessibility of unmodified peptides and thus the specificity of the recognition of methylated peptide epitopes can be probed using the in situ methylation procedure described here.
Covalent Conjugation of Poly(Ethylene Glycol) to Proteins and Peptides: Strategies and Methods
Time of Update: 2020-12-21
Nevertheless, this technique still requires a certain level of familiarity and knowledge in order to achieve a positive outcome for a PEGylation project.
Hereditary angioedema (HAE) the first oral therapy! FDA approves plasma kinetic peptide release enzyme inhibitor Orladeyo (berotralstat)!
Time of Update: 2020-12-19
it's worth noting that Orladeyo is the first targeted oral therapy approved to prevent HAE seizures, and its approval will make significant progress in the treatment of HAE patients and help reduce the burden of treatment for patients.
The study found that the new endocrine peptide stimulates the plant's PTI immune response and disease mold resistance
Time of Update: 2020-12-18
Recently, Journal of Integrative Plant Biology published online a research article by a team of single-satellite professors at the Agricultural College entitled "The novel peptide NbPPI1 identified from Nicotiana benthamiana triggers immune responses and enhances resistance againstst Phytophthora pathogens".
Preparation of Peptide and Other Biomolecular Conjugates Through Chemoselective Ligations
Time of Update: 2020-12-17
on the preparation of chemoselectively addressable peptides allowing successive oxime ligations and/or alkyne–azide cycloaddition (“click”) reactions of various biomolecules. This modular synthetic approach can be applied to a broad range of purposes.
Capillary Electrophoresis-Mass Spectrometry for Peptide Analysis: Target-Based Approaches and Proteomics/Peptidomics Strategies
Time of Update: 2020-12-16
These generic methods have broadapplications for the analysis of peptides in a large variety of matrices, including applications in the area of proteomicsand peptidomics.
Peptide Nucleic Acid-Mediated Recombination for Targeted Genomic Repair and Modification
Time of Update: 2020-12-15
clinical value. Triplex formation by syntheticDNA -binding molecules such as peptide nucleic acids (PNAs) has been studied for over 20 yearsand much of the work in the last 10 years has shown its great promise in its use to direct site
Selection of Peptides for Specific Delivery of Oligonucleotides Into Cancer Cells
Time of Update: 2020-12-15
When one of the selected peptides was conjugated to an antisense oligonucleotide against the ErbB2 receptor, specific delivery to breastcancer cells was demonstrated.
Peptide Detection and Structure Determination in Live Cells Using Confocal Raman Microscopy
Time of Update: 2020-12-14
In this chapter we describe an experimental methodologyfor the detection and structure determination of exogenous peptides within living cells using confocal Raman microscopy (CRM).