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Animal Model for In Vivo Evaluation of Cholesterol Reduction by Lactic Acid Bacteria
Time of Update: 2021-01-27
Numerous drugs that lower cholesterol have been used to treat hypocholesterolemic individuals ( 1 ).
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Network Analysis and Protein Function Prediction with the PRODISTIN Web Site
Time of Update: 2021-01-27
In this context, the PRODISTIN Web site is dedicated to the clustering of network proteins according to the identity of their interaction partners, and to the subsequent functional annotation of these clusters.
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Electrophysiological Characterization of Bacterial Pore-Forming Proteins in Planar Lipid Bilayers
Time of Update: 2021-01-27
Together with patch-clamp, the planar lipid bilayer technique is one of the electrophysiological approaches used to study the biophysical properties of bacterial pore-forming proteins.
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βLactam Resistance Mediated by Changes in Penicillin-Binding Proteins
Time of Update: 2021-01-27
Alternatively, in some Gram-negative bacteria, resistance may have arisen by a reduction in the ability of the antibiotic to access its target.
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Sci Adv: Scientists have identified EGR1, the "guardian protein" of human macrophage inflammatory enhancers
Time of Update: 2021-01-26
JANUARY 19, 2021 // -- In a recent study published in the international journal Science Advances, scientists from the Westa Institute and others in the United States found that a protein that turns on and off the expression of special genes during
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Progress has been made in the study of the mechanism by which central body protein regulates brain development
Time of Update: 2021-01-26
the study revealed a new mechanism by which central proteins affect the development of the cerebral cortical layer by regulating bonding connections.
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Import of Precursor Proteins Into Isolated Yeast Mitochondria
Time of Update: 2021-01-26
The process of mitochondrial protein import can be reconstituted in vitro using isolated mitochondria and in vitro synthesized precursor proteins.
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Scale-Up of recombinant virus and protein production in Stirred-Tank reactors
Time of Update: 2021-01-26
Depending on the quantity required, bioprocesses can vary in complexity from short-term (5-7 d) batch cultures to longer-term fed-batch (7-10 d) or perfusion processes (7 to 2 30 d).
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Quantifying Plasmid Copy Number to Investigate Plasmid Dosage Effects Associated with Directed Protein Evolution
Time of Update: 2021-01-26
We have observed that when random mutations are not restricted to the coding sequence of the target genes, directed evolution results in a strong positive selection of plasmid origin of replication ( ori ) mutations.
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Mitogen-Activated Protein Kinase Pathways in Interferon Signaling
Time of Update: 2021-01-25
There is recent evidence that in addition to the classic JAK/STAT pathways, mitogen-activated proteins (MAP) kinase pathways play important roles in Type I interferon signaling and the generation of interferon responses.
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34 Expression of scFvs and scFv Fusion Proteins in Eukaryotic Cells
Time of Update: 2021-01-25
scFvs have considerable therapeutic potential against antigens (Ags) involved in disease processes ( 1,2) , either as proteins synthesized ex vivo for passive administration, or introduced by gene therapy
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Protein and Vitamin Production in Bacillus megaterium
Time of Update: 2021-01-25
megaterium to a vitamin B12 production host are also described.
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Applications for Green Fluorescent Protein in Cell Signaling
Time of Update: 2021-01-25
Expression vectors are now supplied commercially that allow proteins to be tagged easily ( 6 , 7 ).
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Clin Cancer Res: The activity of the trisexual T-cell activation protein HPN536 in malignant tumors that express mesothionin
Time of Update: 2021-01-25
HPN536 can effectively inhibit tumor growth experimental results confirmed that HPN536 can be combined with tumor cells expressing MSLN, and with the surface of T cells CD3, resulting in T cell activity and effective redirect target cell dissolution.
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Expression of Foreign Proteins in Trichoplusia ni Larvae
Time of Update: 2021-01-24
A large number of eukaryotic proteins have been successfully overproduced in insect cells infected with a natural pathogen, a baculovirus, in which foreign gene coding sequences were placed under the control of the viral polyhedrin gene promoter.
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The Harvard study found that Tau protein affects cognitive function differently between men and women
Time of Update: 2021-01-24
, there have been few reports of results from tau-positive electron emission fault scanning (PET) to explore the gender differences in the distribution of tau signal brains.
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What are the new trends in protein degradation in the past year?
Time of Update: 2021-01-23
article, Cullgen developed two new TRK-targeted protein degradation agents: CG416 and CG428, designed to address side effects and drug resistance in patients taking TRK inhibitors.
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Oat milk brand OATLY a number of products debuted, to create a new fashion of plant protein adornment drinks
Time of Update: 2021-01-22
The 6th Guangzhou International Hotel Supplies and Catering Expo (HOTELEX Guangzhou Exhibition) once again landed in the Millennium Merchants Capital, more than 600 high-quality exhibitors at home and abroad gathered in nine pavilions, leading
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China's first panorama of the molecular pathology of protein molecules of the new crown deceased
Time of Update: 2021-01-22
death pathogenesies and to provide accurate interventional treatment to patients. This is the first time in the world from the protein molecular level, the new coronavirus infection of the human body after a number of key organs of the response
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Scientists have identified EGR1, the "guardian protein" of human macrophage inflammatory enhancers
Time of Update: 2021-01-22
Researcher Professor Alessandro Gardini said: 'By understanding the role of EGR1 in depth, we can shed light on the basic processes of macrophage maturation, which is necessary for many of the body's immune responses, including inflammatory processes
