>. Within 30 days of obtaining the virus sequence information, the whole process from vaccine production, mouse immunization to efficacy evaluation was completed .
Nature: Li Ming's team discovered a new type of T cells with stronger anti-cancer ability, bringing new hope for solid tumor immunotherapy
Time of Update: 2022-05-20
, which revealed a new mechanism of immune anti-cancer . >At 23:00 on April 20, 2022, the team
Diabetologia: Early and late histological confirmation of celiac disease in children with new-onset type 1 diabetes
Time of Update: 2022-05-19
>>Table 1 Adjusted outcome variables for participants with early versus delayed histological diagnosis of celiac disease (n = 411) at the last follow-up visit>>Figure 2 SDS
This type of pharmacy requires a 3-year medical insurance qualification with a licensed pharmacist!
Time of Update: 2022-05-19
area . Pharmacies applying to be included in the outpatient co-ordination must also have the following qualifications: 3 years or more (including 3 years) of designated medical insurance within
NICE recommends Koselugo for neurofibromatosis type 1
Time of Update: 2022-05-18
Therefore, this Phase II trial concluded that most children with neurofibromatosis type 1 and inoperable plexiform neurofibromas experienced significant clinical benefit with Koselugo .
Hong Kong University of Science and Technology: How RNA elements control the cleavage activity of DICER enzymes in pre-miRNAs and short hairpin RNAs
Time of Update: 2022-05-18
A research team led by scientists from the Hong Kong University of Science and Technology has revealed how secondary structural RNA elements control the cleavage activity of DICER enzymes in pre-miRNAs and short hairpin RNAs .
EHJCP: Cost-effectiveness of ticagrelor in patients with type 2 diabetes and coronary artery disease
Time of Update: 2022-05-17
In some European countries, ticagrelor plus aspirin may be more cost-effective than aspirin alone in patients with T2DM and coronary heart disease without prior myocardial infarction or stroke, according to the THEMIS study .
Diabetologia: Characteristics of Type 1 Diabetes and Refractory Hypoglycemia in Adults
Time of Update: 2022-05-17
AHN, normalization of asymptomatic hypoglycemia; HAP, avoidance of hyperglycemia prioritized; HCM, minimized hypoglycemia problems;Figure 2 k-means cluster analysis of the HARPdoc cohort with two clusters .
Nature Communications: Novel mechanism of PD-L1 regulation by RNA-binding protein DENR
Time of Update: 2022-05-16
, Nose and Throat Hospital jointly published a paper entitled DENR controls JAK2 translation to induce PD-L1 in Nature Communications. Expression for tumor immune evasion research paper, which revealed a new mechanism by which RNA-binding protein
J Periodontal Res: Is the presence of herpes simplex virus type 1 (HSV-1) associated with the development of gingivitis and periodontitis?
Time of Update: 2022-05-16
A meta-analysis of observational studies published in J Periodontal Res aims to investigate the strength and prevalence of the association of herpes simplex virus type 1 (HSV-1) in subjects with plaque-induced gingivitis and periodontitis .
, possibly related to adenovirus type 41, possibly fulminant adenovirus hepatitis
Time of Update: 2022-05-16
and amino acid sequence homology of Fiber gene was greater than 97%, and it was mainly divided into four evolutionary branches (Ⅰ, Ⅱ, Ⅲ and Ⅳ), among which Ⅰ and Ⅲ were the main popular branches, Branch Ⅰ is mainly popular in China, while branch Ⅲ
Cardiovasc Diabetol: Mechanisms of antihypertensive effects of dapagliflozin, exenatide and their combination in patients with type 2 diabetes
Time of Update: 2022-05-15
Since reductions in plasma volume and (arterial) blood pressure do not increase heart rate (HR), it has been suggested that sympathetic nervous system (SNS) activity will also decrease .
Researchers discover 5,500 new RNA viruses in ocean
Time of Update: 2022-05-15
While the team found hundreds of new RNA virus species that fit within these existing classifications, their analysis uncovered thousands more and grouped them into five newly proposed phyla: Tara aviricota , Pomiviricota, On-axis viricota, Wamoviricota and Arctiviricota .
JAMA Netw Open: Impact of web-based management guidelines on risk factors in patients with type 2 diabetes and diabetic nephropathy
Time of Update: 2022-05-15
Changes in Cardiometabolic Risk Factors and Medication Status by Intention-to-Treat Population Randomization from Baseline to 12 MonthsConclusions: This trial found that 12 months of technology-assisted team care improved multiple treatment goals .
A new type of human well-being drug is coming!
Time of Update: 2022-05-15
Sales of terminal opioid analgesics in public medical institutions in China (unit: 10,000 yuan) Source: Minet .
The Lancet: The third shot of a different type of new crown vaccine is better
Time of Update: 2022-05-15
A recent study in Brazil showed that both homologous and heterologous boosters (BNT162b2 and AZD1222) were safe and immunogenic following completion of two doses of Sinovac vaccine .
Five types of knee arthritis that are easy to confuse, finally understand
Time of Update: 2022-05-14
Most of the patients suffer from middle-aged and elderly people, and their symptoms are mostly manifested as knee swelling and pain, pain when going up and down stairs, and knee pain and discomfort when sitting, standing, and walking .
A new type of cell death has been discovered!
Time of Update: 2022-05-14
New research challenges this hypothesis, providing evidence for a second type of programmed cell death that may target the gut .