European wheat market week focus: export demand supports French wheat to continue to rise
Time of Update: 2022-12-29
Foreign media news on November 27: In the 45th week of 2022, French wheat spot prices continued to rise, continuing to be supported by active export demand, especially the United States ordering European wheat, providing additional support for the market.
The new method thoroughly reveals the strong impact of genome copy number changes on human health
Time of Update: 2022-10-31
"Being able to delve into the potential of these variants gives us more opportunities to discover the ways in which genetic variants affect human phenotypes," said Po-Ru Loh, an associate member of Broad, senior author of the study and an assistant professor at Brigham and Women's Hospital and Harvard Medical School.
Aims to functionally cure hepatitis B
Time of Update: 2022-02-22
▲ siRNA inhibits the expression of multiple hepatitis B virus genes (Image source: Roche’s official website) Previously published phase 1 data showed that after 4 months of subcutaneous injection in chronic hepatitis B patients, HBsAg continued to decrease for up to 1 year, and it was safe The performance was favorable, with no patients experiencing serious adverse events (SAEs), and there were no dose-limiting toxicities or safety-related discontinuations .
[JMC] You Qidong/Wang Lei, etc.: Research progress of small molecule targeting serine protein phosphatase (PPPases
Time of Update: 2021-08-08
Although they play a common mechanism of dephosphorylation through highly conserved catalytic active sites, different pppases show specificity according to their different regulatory subunits or unique structural features, which provides potential for the rational design of small molecules.
It coincides with the time that the 14th Geriatric Oncology Conference-Oncolytic Virus Therapy Symposium was grandly held
Time of Update: 2021-08-06
Among them, the results of a phase I clinical study of H101 combined with standard therapies for the treatment of liver metastases from colorectal cancer led by Professor Xu Qing from Shanghai Tenth People’s Hospital showed that no dose limitation was observed in terms of safety.
NSMB Xu Dong Group Reveals New Pathogenesis of Fanconi's Anemia
Time of Update: 2021-06-22
On June 10, 2021, the research group of Dongyi Xu from the School of Life Sciences, Peking University published an article Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress on Nature Structural & Molecular Biology, and found that the FA pathway is essentially A break-induced replication (BIR) pathway is used to repair stagnant replication forks, and the view that sustained replication pressure is a potential endogenous cause of FA symptoms .
In Vivo Analysis of Protein Translocation to the Escherichia coli Periplasm
Time of Update: 2021-03-04
Alkaline phosphatase (PhoA), an enzyme only active after export to the periplasm, provides the best and most versatile quantitative reporter for protein translocation studies.
Cleavable signal sequences can be used to monitor protein export in a time frame of 15–120 s.
Scientists have found an actin histidine methyltransferase that can prevent primary dystocia
Time of Update: 2018-12-21
On December 10, researchers from Stanford University and the University of Texas published an article titled "setd3 is an actin histidine methyltransferase that prevents primary dystocia" in nature Th
China's demand for new vaccines will reach 800 billion
Time of Update: 2013-05-03
2013-05-03 source: Fu Mingzhong, executive chairman of China Pharmaceutical Business Association, Shanghai Securities News, predicted at the 69th pharmaceutical fair that the biomedical industry is ex