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Sci Transl Med: LRRK2 mediates small glial cytotoxicity through NFATc2 synactogenesis
Time of Update: 2020-10-29
-syn α actoid nucleoproteins released by neurons induce neurotoxic, inflammation-promoting small glial cell reactions through Toll-like subject 2, but their molecular mechanisms are unclear.
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JNNP: Anthoimaging Abnormality and Prognosis after Acute Ishemic Stroke: Intensive Control (ENCHANTED) Trial
Time of Update: 2020-10-29
The results of the Third International Stroke Trial (IST3) showed that brain imaging signs of acute cerebral ischemia and markers of "brain weakness" could be used individually or in association to predict clinical outcomes and symptomatic intracranial hemorrhage (sICH).
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PNAS: Cell membrane nanocystic bubbles, a new treatment to relieve neocyto pneumonia
Time of Update: 2020-10-29
for the first time, the study used genetically engineered cell membrane nanocystic bubbles to act as "baits" to compete with host cells, able to adsorb both viral and inflammatory cytokines, effectively protecting host cells from COVID-19 coronary pneumonia.
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NEJM: Tocilizumab is used for the treatment of hospitalized patients with neo-coronary pneumonia
Time of Update: 2020-10-29
14 days, 24.6 percent of patients in the Tocilizumab group and 21.2 percent in the placebo group were still receiving oxygen.
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Redsiway summary clinical trial results released to focus on new developments in new crown therapy
Time of Update: 2020-10-29
patients in the group, and on the same day, Vir Botechnology/GSK announced that the COMET-ICE study for early neo crown patients with a higher risk of hospitalization in VIR-7831 and antibody therapy had been extended to Phase III globally, incorporating
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Science: One Arrow, CD74 Protein Inhibits Both Ebola and the New Coronavirus
Time of Update: 2020-10-29
that directly inhibits CIITA and causes class II MHC molecules to be lowered, which may help EBOV escape immune system recognition. finding host factors for targeted treatment can limit replication of viral families and may be an effective way to combat
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Scientists have successfully developed a new combination therapy for breast cancer
Time of Update: 2020-10-29
photo source: (c) Kelvin Yip - Monash MicoImaging (MMI) researchers also found that the absence of PTEN function increases levels of glucocorticoid receptors (GR, glucocorticoid receptors) and makes tumor cells more prone to death.
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The total budget of the regional point method and the payment by disease score have an impact on the geometry of pharmaceutical companies
Time of Update: 2020-10-29
this paper, the author tries to explore the "regional points method total budget , pay by disease score , big data regulatory use" on the pharmaceutical companies what impact?
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Science Advances : Significant progress! For the first time, Yu Ying of Shanghai University of Science and Technology has established genetic evidence of cardiovascular risk caused by anti-tumor drugs
Time of Update: 2020-10-29
, the findings establish a link between causal allegens of cardiovascular disease genes and pharmacological regulation, which can facilitate the discovery of cancer drugs and clinical trial design.
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PNAS: The use of cell bait to trick the new coronavirus reduces cytokine production
Time of Update: 2020-10-29
/> he has seen reports of the use of baited subjects to trick pathogens such as HIV, and wondered if the emerging technology could work for SARS-CoV-2. To find out, the researchers fused membranes from the human monocyte THP-1, a cell line from
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Science: Heavy! Why is the new coronavirus highly contagious? Scientists have found their "weaknesses
Time of Update: 2020-10-29
cells with artificial and naturally occurring viruses that mimic SARS-CoV-2 have shown that NRP-1 can promote infection in the presence of ACE2, and that infection can be suppressed by blocking NRP-1 with antibody specificity. NRP1 promotes
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Nails, peeling onions, through bamboo poles! Multi-province start the drug collection order gun
Time of Update: 2020-10-29
, has officially opened the frame, demarcated the runway, fired shots to run. Overall, by 2022 the provincial centralized procurement presents the following characteristics of playing: - nail nails, first find the right position and direction
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Brush the paint so that acceptance
Time of Update: 2020-10-29
the appearance of the wall paint acceptance mainly involves whether the color is uniform, no color difference, whether the wall has cracking, dropping powder, permeable bottom, leakage brush and so on.
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Emperor Zeus Industrial Wu Wei: Do powder coating promoter to create a coating ecosystem
Time of Update: 2020-10-29
According to statistics, China's total sales of powder coatings in 2018 nearly 2 million tons. With the national environmental protection high pressure and green development requirements in recent years, China's "paint powder" trend accelerated
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Diabetes Obes Metab: The relationship between obesity in people with type 2 diabetes and severe COVID-19 outcomes
Time of Update: 2020-10-29
in the multivariable adjustment model, the main outcome (i.e. IMV and/or death on the 7th day) and overweight (OR is 1.65 (1.05-2.59)), I-level (OR 1.93 (1.19-3.14)) and Type II/III obesity (OR 1.98 (1.11-3.52)).
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Bio-based reactive thinner derived from cashew phenol
Time of Update: 2020-10-29
The results showed that the viscosity and volume shrinkage of the UV-cured PUA system decreased significantly after the cashew phenol monomer was added, while maintaining a high bio-renewable content .
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Bio-based reactive thinner derived from cashew phenol
Time of Update: 2020-10-29
The results showed that the viscosity and volume shrinkage of the UV-cured PUA system decreased significantly after the cashew phenol monomer was added, while maintaining a high bio-renewable content .
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Bio-based reactive thinner derived from cashew phenol
Time of Update: 2020-10-29
The results showed that the viscosity and volume shrinkage of the UV-cured PUA system decreased significantly after the cashew phenol monomer was added, while maintaining a high bio-renewable content .
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Immunocytology using the HA epitope
Time of Update: 2020-10-28
The cells are covered with PBS/0.1% BSA, which is allowed to sit for 5 minutes before aspiration.
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High-efficiency liquid phase layering (HPLC
Time of Update: 2020-10-28
operating speed with computer control, and according to certain requirements to change the composition of the flow phase, to improve the separation effect. generally with trace syringes directly into the sample, can also be used six-way valve
