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The State Food and Drug Administration conditionally approves the marketing of Pratinib capsules

 Time of Update: 2021-04-21

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This variety is used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) adult patients who have previously received platinum-containing chemotherapy
Sci Rep: Research reveals biomarkers of adult neural stem cells

 Time of Update: 2021-04-21

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-align: center;">(Image source: www. pixabay. com) "The ultimate goal of our research is to maintain the level
Nature: Early training can delay the occurrence of Rett syndrome

 Time of Update: 2021-04-21

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The authors found that in the mouse model of Rett syndrome, intensive training before the onset of symptoms can significantly improve the performance of specific exercise and memory tasks, and greatly delay the onset of symptoms.
Science: A major breakthrough

 Time of Update: 2021-04-21

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Anna Mäkelä, a postdoctoral researcher in the Saksela laboratory, is coordinating a project funded by the Finnish Academy of Sciences to study the application of CAR-T cell therapy on various cancer types and their surface structures.
Kelun Pharmaceutical obtained the drug registration certificate for sunitinib malate capsules

 Time of Update: 2021-04-21

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On March 24, Kelun Pharmaceutical issued an announcement that its subsidiary Hunan Kelun Pharmaceutical recently obtained the "Drug Registration Certificate" for the chemical drug "Sunitinib Malate Capsules" approved and issued by the National Medical Products Administration.
Nature: Significant progress

 Time of Update: 2021-04-20

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html Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH
Liu Jinyao AM, Institute of Molecular Medicine, Shanghai Jiaotong University: Putting a multifunctional coat on probiotics to enhance the therapeutic effect of enteritis

 Time of Update: 2021-04-20

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Innovation: Professor Liu Jinyao's research group from the Institute of Molecular Medicine of Shanghai Jiaotong University realized the multifunctional modification of the cell surface by adding other functional molecules during the dopamine polymerization process.
Nat Hum Behav: New research links genes to the function of the human brain

 Time of Update: 2021-04-20

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This separation can be traced back to gene expression in specific cell types and molecular pathways, providing key insights for future research on mental illness.
Theory-Mechanism-Clinical, multi-target intervention of Jinlida granule has significant effect on diabetes

 Time of Update: 2021-04-19

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gave an in-depth explanation on the prevention and treatment of diabetes and the clinical application of Jinlida granules guided by collateral disease theory. The audience brought a wonderful academic feast. This article
The pilot product is conditionally approved for the clinical real-world data application of marketed drugs to open a new stage

 Time of Update: 2021-04-19

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for Drug Evaluation began to organize experts to compile guidelines for real-world evidence to support drug development and review, and to answer questions about real-world research data sources and real-world evidence to support drug regulatory
Cell Reports | Li Xuekun/Yi Wen/Shu Qiang team reveals the molecular mechanism of glycosylation regulating adult neurogenesis

 Time of Update: 2021-04-19

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In summary, this work clarifies that Ogt-mediated O-GlcNAc modification regulates the Notch signaling pathway by antagonizing Itch-mediated Notch1 ubiquitination, thereby maintaining the important mechanism of mouse adult neural stem cell homeostasis and adult neurogenesis.
Faced with the threat of viruses, how can I improve my own immunity

 Time of Update: 2021-04-19

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This study shows that serine metabolism can inhibit ATP6V0d2-mediated YAP lysosomal degradation, thereby regulating antiviral innate immunity.
Nature: The new environment restarts neural circuits and promotes learning

 Time of Update: 2021-04-19

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The authors of this study novelly reset the neural circuit connecting the ventral hippocampus (vHPC) and mPFC, and promoted the ability to overcome established strategies.
Nature | Autologous Ileum Organ Transplantation for Short Bowel Syndrome

 Time of Update: 2021-04-19

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The results show that xenotransplantation of ileal organoids will construct the villi structure of small intestinal epithelial tissue, and the reconstructed villi structure will express proteins related to nutrient transport.
The world's fifth CAR-T is approved, BMS and Gilead each have two equal shares, Novartis is surpassed

 Time of Update: 2021-04-19

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On March 27, the FDA official website announced that it had approved Abecma, the first CAR-T cell therapy targeting BCMA for the treatment of multiple myeloma (MM) in adults.
Treat chronic pain

 Time of Update: 2021-04-19

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Participants who successfully registered for the Shanghai 2021 BPIT conference will receive a limited edition of "CAR-T Cell Therapy Industry Research Report" 2021.
Scientists prove that there is an alert line in the mouse retina

 Time of Update: 2021-04-19

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, which can transmit signals at the fastest speed like cables, make them the first choice for this special alert line. However, research on such hot star cells has been slow for a long time, because although
Eli Lilly's IL-2R agonist application clinical

 Time of Update: 2021-04-19

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>In June 2020, Eli Lilly and Nektar jointly announced the phase Ib clinical study data of NKTR-358 for patients with moderate to severe systemic lupus erythematosus (SLE). >

Recall of 4 batches of injections caused by solution crystallization

 Time of Update: 2021-04-19

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Injection produces crystalsInjection produces crystalsRecall announcementRecall announcementAfter receiving several complaints about injection crystallization, Zydus Pharmaceutical Company in the United States voluntarily recalled four batches of acyclovir sodium injection 50 mg/mL, with two packaging specifications of 10 mL and 20 mL.
Gut | Significant progress

 Time of Update: 2021-04-19

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The study was conducted on 6 people The matched primary tumors, adjacent non-cancerous mucosa, liver metastases, and multiple areas of lung metastases (n = 74) of CRC patients were sequenced with whole exomes.

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