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【Nature】Sports addictive? Scientists reveal gut-brain axis signals that amplify the effect of motor reward
Time of Update: 2022-12-30
1038/s41586-022-05525-zThe images in the article are from referencesFigure 1: Reduced motor skills in mice after antibiotic treatment2Striatal dopamine drives mouse locomotionThe striatum is a key brain region that drives motivational behavior.
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Babies will inspire the "dad brain" of the new dad
Time of Update: 2022-10-13
Comparing the results of fathers' scans before and after the baby's birth, it can be seen that the part of the cerebral cortex responsible for processing visual information and the part of the brain's default pattern network have changed.
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Science article: Liu Mofang's group discovered that phase separation mediates an important mechanism of protein translation activation during sperm development
Time of Update: 2022-08-20
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New progress in targeted protein degradation
Time of Update: 2022-05-24
▲The mechanism of action of AUTOphagy-TArgeting Chimera (AUTOTAC) (Image source: Reference [1])Based on this concept, the researchers developed a variety of small-molecule compounds capable of activating p62 and tested their ability to degrade soluble proteins in vitro .
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mRNA cancer vaccine obtains FDA fast track qualification to treat melanoma
Time of Update: 2021-12-01
“The FDA’s grant of Fast Track status underscores the potential of our FixVac platform, which is expected to solve the current treatment challenges faced by melanoma patients .
"Reference materials:Reference materials:[1] BioNTech Receives FDA Fast Track Designation for its FixVac Candidate BNT111 in Advanced Melanoma.
Retrieved November 19, 2021, from https:// /BioNTech-Receives-FDA-Fast-Track-Designation-for-its-FixVac-Candidate-BNT111-in-Advanced-Melanoma.
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Microgeo develops the first biological additive for fertilizers in Brazil
Time of Update: 2021-05-08
html" class="zdbq" title="Additive-related food information" target="_blank">Additive Caio Suppia, Microgeo's marketing director, said that this biological additive is made from natural solutions, which improves the biological quality of mineral fertilizers and enhances its functions and effects.
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Scientists prove that there is an alert line in the mouse retina
Time of Update: 2021-04-19
The study screened the molecular markers of transient light-exhausted alpha retinal ganglion cells and constructed transgenic mice that can label and manipulate the cells, and found that such cells can encode the size of the approximate visual stimulus, and mediate the approximate visual stimulus trigger The instinctive defensive response of mice.
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Misexpression Approaches for the Manipulation of Flower Development
Time of Update: 2021-01-13
The generation of dominant gain-of-function mutants through activation tagging is a forward genetic approach that complements the screening of loss-of-function mutants and that has been successfully applied to studying the mechanisms of flower development.
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Advances were made in the study of blood lymphocysis and autophagy immunology in marine invertebrates
Time of Update: 2021-01-05
Yu Zinu, a researcher at the South China Sea Oceanographic Research Institute of the Chinese Academy of Sciences and author of the paper, said the study systematically revealed key regulatory events for oyster cell immunity and proposed new mechanisms for blood lymphocyte differentiation and autophagy activation.
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The application of cellulose enzymes is progressing
Time of Update: 2020-10-22
That is to say, cellulose enzymes, in addition to directly degrading cellulose, promote its decomposition into low molecules compounds that are easily digested and absorbed by animals, but also work with other enzymes to improve the breakdown and digestion of feed nutrients in livestock and poultry.
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A major breakthrough in first-line treatment of liver cancer! Roche's cancer immunization programme Tecentriq and Avastin (Tai Sanqi and Avetin) is about to be approved by the European Union
Time of Update: 2020-10-06
!--, 22 September 2020 // -- Roche has announced that the European Medicines Agency (EMA) Commission on Human Pharmaceutical Products (CHMP) has issued a positive review recommending approval of anti-PD-L1 therapy Te Centriq (Tai Sanqi, generic name: atezolizumab, atilijutatin monoanti) in a joint Avastin (Avistin, generic name: bevacizumab, beva bevajuumab) is used to treat adult patients with non-excisive or metastatic hepatocellular carcinoma (HCC) who have not been systematically treated in the past.
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A neural model of mutual antagonism between hunger and maternal behavior
Time of Update: 2020-08-06
combined with the team's previous research on the suppression of hunger in pups (Han et al., Neuroscience, 2017) and the study of the inner pre-visual area Esr1 plus neurons to control the behavior of cubs (Wei et al., Nature Communications, 2018), the paper presents a neural model of mutual adyment between hunger and maternal behavior (see chart).
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JAMA: The "cause" of Alzheimer's disease, a gene that drives the brain's amyloid plaques for the first time
Time of Update: 2020-07-19
doi:10.1001/jamaneurol.2020.1760 Specifically, to find the genes that drive the early accumulation of amyloid, the latest study examined the genomes of 4300 people whose PET images showed amyloid deposition in the brain but had not yet developed Alzheimer's disease.
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Nat Commun: Optogenetics can control monkey movement
Time of Update: 2020-07-15
, July 7, 2020 /PRNewswire/ -- Biovalley BIOON/--- Optogenetics is a recently developed genetic modification technique that can be genetically modified to import photosensitive proteins into cells an
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Dr. Hu Xiang, North Branch Biology: Small Cells Are Related to Big Health
Time of Update: 2020-06-26
Read: Hear the story of this cell pioneer's struggle in the 1960s, Hu Xiang was born in Guizhou Province, a strong medical style of the family, ear-to-ear, Hu Xiang small age set up the ambition of
