Nature of Central South University published an article: A novel metabolic mechanism of iron death in tumor cells
Time of Update: 2023-02-03
Professor Yang Minghua's team of Pediatrics from the Third Xiangya Hospital of Central South University published original research results entitled "The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis" in the international authoritative academic journal Nature Communications, revealing the novel metabolic mechanism of iron death in tumor cells.
Nature of Sichuan University published an article on the development and verification of the whole process of clearance of mouse pancreatic tumors by a Pin1 inhibitor delivery system based
Time of Update: 2023-01-05
engagement。 In this study, a prolyl isomerase PIN1 inhibitor delivery system based on CAFs-targeted antibodies and DNA barcode bundle gel system was developed, which introduced CD8+ T cells into tumors with CD8+ T cell-specific aptamers, achieved pancreatic tumor clearance in in an in situ model of mouse pancreatic cancer, and realized the treatment of mouse pancreatic cancer by reshaping the tumor microenvironment.
Toyota's fuel cell project settled in Beijing
Time of Update: 2022-11-04
Toyota China announced on October 24 that the groundbreaking ceremony for Toyota's fuel cell R&D and production project (phase I) was held in the Beijing Economic and Technological Development Zone.
New enzyme inhibitors promise to treat cancer and autoimmune diseases
Time of Update: 2022-10-31
Marlene Bouvier, corresponding author of the study and professor of microbiology and immunology at the UIC School of Medicine, said: "Tumors have the ability to present cell surface markers in the form of non-autopeptide antigens or neoantigens, which makes them very sensitive to the recognition and elimination of T cells, which are immune cells that kill tumor cells when they recognize neoantigens.
How the body recognizes beneficial bacteria
Time of Update: 2022-10-03
Trillions of bacteria and other microbes thrive in our gut microbiome, and over the past decade, scientists have become increasingly aware of the important role they play in creating a healthy gastroi
Focus on lupus to explore how to predict disease onset in systemic lupus erythematosus
Time of Update: 2022-08-11
In a recent study, Dr. John Tsang, co-director of the NIH Center for Human Immunology (CHI), and his team built on previous work to use SLE as a model to study vaccine responses to healthy populations and disease activity in SLE Sex-related common baseline gene expression signatures .
The courier is a blockbuster
Time of Update: 2022-06-05
▎WuXi AppTec Content Team Editor Today, Nkarta announced that the company's two major chimeric antigen receptor (CAR) natural killer (NK) cell candidate therapies, NKX101 and NKX019, are in two early-stage treatments for different blood cancer patient populations.
Mutation 'hot spots' reveal new cancer-inducing factors
Time of Update: 2022-03-08
The researchers found that "cluster of somatic mutations" induced cancer progression in about 10 percent of people, and understanding them could predict patient survival .
The researchers also identified various factors that lead to cluster somatic mutations .
In Q3 2021, the sales of two blockbuster monoclonal antibodies exceeded 5 billion yuan
Time of Update: 2022-03-06
However, from the perspective of the market structure, the current domestic bevacizumab injection market is mainly divided by the original researcher Roche and Qilu Pharmaceutical .
. However, with the entry of domestic pharmaceutical companies, the industry expects that the Roche bevacizumab injection market will be impacted in the future.
Science: High-fiber diet can improve immunotherapy for patients with melanoma
Time of Update: 2022-01-10
According to a latest large-scale international collaborative study, when patients with melanoma receive immunotherapy, if their diet is rich in fiber, their immune system is more likely to kill cancer cells and produce a better response to the therapy .
Eating a "healthy" food frequently will double your risk of cancer
Time of Update: 2021-12-27
However, when one fish is caught in open water and the other fish is raised in a confined space, this may have an impact on healthAccording to a large study published by Harvard Health in 2004, the concentration of PCBs in farm-raised salmon is approximately eight times the concentration of PCBs in wild salmon Polychlorinated Biphenyls (PCBs) are man-made chlorinated industrial chemicals .
JCO: The prognosis of stage 3 gefitinib vs. cisplatin + vinorelbine for adjuvant treatment of non-small cell lung cancer after surgical resection
Time of Update: 2021-11-13
Although cisplatin-based adjuvant chemotherapy is the standard treatment for stage II and stage III non-small cell lung cancer ( NSCLC ) that are completely resected by surgery , the survival prognosis of patients is not satisfactory .
Release of the largest and highest resolution gastric cancer map to date
Time of Update: 2021-11-13
With the help of precision oncology, With cutting-edge technologies such as single-cell sequencing, we have drawn maps that can analyze patients with unprecedented depth and resolution, tailor treatments for patients, and reveal new ways to improve diagnosis and treatment .
Why is ginger spicy
Time of Update: 2021-11-11
After a long period of nutrient accumulation, the content of gingerol in old ginger is higher than that in new ginger, so naturally old ginger is more spicy .
The ginger will produce a substance called safrole during the rotten process .
Molecular Cancer Li Liaoyuan’s team at Sun Yat-sen University has constructed a urine extracellular vesicle circRNA classifier to better diagnose prostate cancer
Time of Update: 2021-10-02
To this end, the study used RNA sequencing to identify candidate circRNAs from the urine extracellular vesicles of 11 high-grade prostate cancer patients and 11 case-matched benign prostatic hyperplasia patients .