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Keyue Pharma announced the complete data of the phase I clinical trial SYNERGY-1 of KP104
Time of Update: 2022-11-14
Details of the presentation are below : SYNERGY-1: Phase I, first-in-human study evaluating the safety, tolerability, immunogenicity, and single- and multiple-dose escalation of KP104 for PK104 By Paul Wabinitz1, Xiang Gao2, Jay Ma2, Ping Tsui2, Martin Rabe2, Helen Fu2, Chaomei He2, Jingtao Wu2, Brian York2, Qing Yu Christina Weng 2,3, Jon Rankin4, Frederick Beddingfield 2,5, Wenru Song2、Nicholas Farinola1、Richard Lee2 Abstract number: 3761666 Session Name: Glomerular Disease: IgA and Complement-mediated Glomerulonephritis[PO1302-3] Conference date and time: November 5, 2022, 10:00 a.
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The meningocaudal sign is not exclusive to meningioma
Time of Update: 2022-11-04
It is not necessarily a meningioma, but it may also be lymphoma, metastases, malignant glioma, primitive neuroectodermal tumor, melanoma, plasma cell granuloma, infectious meningitis, eosinophilic granuloma, Wegener granuloma, etc【Classic case】1.
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Scientists have discovered the genes responsible for the human brain
Time of Update: 2022-11-01
"Reference: Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids A brain organ about 3 mm in size made from stem cells of chimpanzees.
"Reference: Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids A brain organ about 3 mm in size made from stem cells of chimpanzees.
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Zebrafish have a unique set of proteins that restore hearing
Time of Update: 2022-09-20
Dr. Erin Jimenez, a postdoc in the laboratory of Dr. Shawn Burgess, a senior researcher at the Translational and Functional Genomics Branch of the National Human Genome Institute (NHGRI), led the study in collaboration with Dr. Ivan Ovcharenko and Dr. Wei Song of the National Center for Biotechnology Information at the National Library of Medicine.
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All cells matter: a roadmap for lymphoma stromal characterization
Time of Update: 2022-05-19
Researchers at the University of Tsukuba identified gene expression signatures in different types of lymph node cells that play an active role in the development of lymphoma .
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Express treatment of solid tumors, TCR cell therapy with stem cell characteristics enters the clinic
Time of Update: 2022-02-20
S. FDA has approved the IND application for a Phase 1 clinical trial of the investigational T cell receptor (TCR) therapy LYL132 for the treatment of New York esophageal squamous cell carcinoma patients with solid tumors with neoplasm 1 (NY-ESO-1) antigen .
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Radiology: Dual-energy CT perfusion, making imaging at the forefront of non-small cell lung cancer evaluation
Time of Update: 2022-01-23
Several recently published studies have shown that dual-energy CT can obtain mean iodine concentration measurements throughout the tumor volume to predict the effect of tumor chemotherapy and further reflect its relationship with postoperative prognosis .
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Cell: Possible Alternative Therapy for Lyme Disease
Time of Update: 2021-10-19
Hygromycin A can eliminate mice ( Including animals that ingest the compound in the bait, Borrelia burgdorferi is infected, and the damage to the fecal microbiota is less than that of clinically relevant antibiotics .
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Hausen's Class 1 new drug "Peihuaxi hippocampus" declares for listing
Time of Update: 2021-10-10
Article source: Medical Rubik's Cube InfoAuthor: Shi BeiOn September 30, the official website of CDE showed that the listing application for Peihuaxi hippocampal peptide injection, a new class 1 drug of Hausen Pharmaceuticals, was accepted by the State Food and Drug Administration .
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A new gene delivery vector can make gene therapy of muscle diseases safer and more effective
Time of Update: 2021-09-20
The team showed that due to this increase in efficiency, MyoAAV can deliver therapeutic genes at doses 100 to 250 times lower than other viral vectors used in other studies and trials, potentially reducing the risk of liver damage and other serious side effects .
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my country's artificial intelligence diagnosis system for malaria parasites is officially launched
Time of Update: 2021-08-04
Academy of Sciences After an exclusive visit to a laboratory of the Military Medical Research Institute by CCTV reporter Su Zhou of the Central Station, he saw that the research personnel of the Military Medical Research Institute can quickly and easily identify the collected malaria parasites through the latest artificial intelligence diagnosis system developed during their assistance in Africa.
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Cell's important finding: The presence of type I natural antibodies similar to 2G12 antibodies in the human body may become a new target for HIV-1 vaccines
Time of Update: 2021-06-22
The author only tested the reactivity of this FDG antibody to recombinant HIV-1 Env and SARS-CoV-2 S proteoglycans, but this may exclude other types of polysaccharide forms in the body .
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Sub-Journal of "Nature": Demystifying the cause of death of specific neurons in AD patients
Time of Update: 2021-06-04
Recently, a new study published in the journal Nature Neuroscience showed that the selective degeneration of neurons is related to the regulation of intracellular immune response by apolipoprotein E (ApoE) [2].
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"Starving" malaria parasites may help develop new antimalarial drugs
Time of Update: 2021-01-05
The study demonstrated the different composition structures of plasmodium falciparum's key protein for energy intake, the hetose transport protein PfHT1, in combination with natural substrate glucose and an inhibitor with weak inhibitor C3361, on the basis of which the team developed a series of selective inhibitors with higher affinity, laying the foundation for the further development of the series of antimalarial drugs.
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Sugar fermentation of microorganisms
Time of Update: 2020-10-21
And add a certain amount of phenolic red indicator and small inverter, made of monosaccharide fermentation tube, inoculated bacteria cultured by 37 degrees C 18 to 24 hours, if you can break down the sugar-producing acid then phenolic red indicator from red yellow, if you can break down the acid has CO2 and H2 gas formation, small inverter is aggregated with air bubbles; (ii), experimental materials 1.
