-
Nature: For the first time, CRISPR is used to insert neoantigens into T cells to treat cancer, paving the way for personalized cancer treatment
Time of Update: 2022-11-25
The research team conducted clinical trials in 16 patients with solid tumors, including breast, lung, and colorectal cancers, which is also the first attempt to combine gene editing and T cell therapy, two hot areas of cancer treatment.
-
Total length 1 km France launches the world's first solar road
Time of Update: 2022-11-23
solar energy Located in Tourouvre-au-Perche, a town of about 3,400 inhabitants in Normandy in northwestern France, the $5.
solar energy Located in Tourouvre-au-Perche, a town of about 3,400 inhabitants in Normandy in northwestern France, the $5.
-
Issue 36/2013 - DSM EcoPaXX polyamide 410 is used in automotive diesel engines
Time of Update: 2022-11-12
(Zhang Wenxuan) Royal DSM (DSM) has joined hands with automotive parts supplier KACO to develop a lightweight and multifunctional crankshaft end cover.
(Zhang Wenxuan) Royal DSM (DSM) has joined hands with automotive parts supplier KACO to develop a lightweight and multifunctional crankshaft end cover.
-
Stem cell-derived organoids mimic parathyroid tissue
Time of Update: 2022-10-31
S-Herto Kluyver, co-senior study author and University Medical Center in Groningen in the Netherlands, said this is the world's first time to isolate parathyroid stem cells and maintain them as organoids for a long time in the laboratory, and the new study uses PTO as a new model for parathyroid disease research.
-
Cell: Zhou Dawang/Chen Lanfen's research group jointly published a paper revealing the important mechanism of glycogen accumulation and phase separation driving the initiation of liver cancer
Time of Update: 2021-11-03
This work found that early liver tumor cells use the extracted glucose to synthesize glycogen as energy storage, and inhibit the activity of the Hippo signaling pathway through liquid-liquid separation, thereby driving the occurrence and development of tumors .
-
Front Oncol: Comparison of the direct efficacy of bevacizumab or pembrolizumab combined with pemetrexed + platinum-based chemotherapy in the first-line treatment of driver-gene-negative advanced non
Time of Update: 2021-10-10
Bevacizumab or pembrolizumab combined with pemetrexed + platinum-based chemotherapy are recommended as first-line treatment for patients with advanced non-squamous non-small cell lung cancer ( NSCLC ) with negative driver genes .
-
Nat Commun Ji Jing's team discovered a new mechanism for prodynein to regulate neuronal death after traumatic brain injury
Time of Update: 2021-08-08
Figure 1 In summary, the team revealed the protective effect of Prok2 on neurons after traumatic brain injury, and further explained the importance of the Prok2-Fbxo10-Acsl4 regulatory axis in inhibiting neuronal iron death and the accompanying lipid peroxidation.
-
High-performance two-dimensional perovskite solar cell prepared by Dalian Institute of Chemical Technology
Time of Update: 2021-06-22
Recently, the team of Liu Shengzhong, a researcher of the Thin Film Solar Cell Research Group of the Solar Energy Research Department of the Dalian Institute of Chemical Physics, Chinese Academy of Sciences, and Zhao Kui, a professor of Shaanxi Normal University, have made new progress in the study of two-dimensional Dion-Jacobson (DJ) perovskite film formation control A high-efficiency aromatic two-dimensional DJ perovskite solar cell was prepared .
-
More than half of the patients achieved complete remission. "Ready-to-use" NK cell therapy has positive early clinical results
Time of Update: 2021-06-22
Recently, Fate Therapeutics announced at the 2021 American Society of Clinical Oncology (ASCO) annual meeting that it announced its research on natural killer cell (NK cell) therapy FT516, combined with rituximab, to treat patients with relapsed/refractory B-cell lymphoma.
-
AstraZeneca/Daiichi Sankyo launches global phase 2 clinical trial: Enhertu treats HER2 mutant lung cancer
Time of Update: 2021-04-14
The trial was carried out in patients with metastatic non-small cell lung cancer (NSCLC) with HER2 mutations during or after receiving at least one previous platinum-containing treatment regimen, and evaluated the targeted antibody conjugate (ADC) Enhertu (trastuzumab).
-
Regenerative meta/Sanofi PD-1 inhibitors were given a second adaptive disorder
Time of Update: 2021-03-08
Today, Regeneron and Sanofi jointly announced that the FDA has approved the PD-1 inhibitor Libtayo (cemiplimab) extended adaptation to treat patients with advanced substrate cell carcinoma (BCC).
" FDA approval today of Libtayo will change the treatment model for patients with advanced substrate cell carcinoma.
-
In-depth inventory: What trends do the FDA represent when it approves 53 innovative drugs this year
Time of Update: 2021-01-02
Photo Source: Pharmaceutical Mingkang content team drawing, as of December 25, 2020 Review 2020, the FDA has approved a total of six drugs with new treatment models (defined as antibody-coupled drugs, gene therapy, cell therapy and oligonucleotide therapy), almost the same number as in 2019 (7).
-
High-efficiency, noninvasure precision sieve platform for patients with bladder cancer Protein & Cell
Time of Update: 2020-12-27
Title: Continuous culture ofurine-derivedbladder cancer cells for precision medicine Journal: Shuai Jiang, Jiaqi Wang, Chen Yang, Renke Tan, Jun Hou, Yuan Shi, Huihui Zhang, Shiyu Ma, Jianan Wang, Me
-
Cell Death Dis: ASC regulates the stability of HIF-1 alpha to induce the metastasis of squamous cell carcinoma in the mouth
Time of Update: 2020-09-24
the study revealed that HIF-1 alpha was involved in asC-induced tumor metastasis.
researchers identified 195 genes associated with cellular movement that were highly SAS_ASC in ASC-expressed cells.
further studies showed that the initiators of these 14 ASC-induced highly expressed genes all contained a binding base sequence of the transcriptional regulator HIF-1 alpha.
-
1 death of severe hand, foot and mouth disease combined with acute necrotised enteritis
Time of Update: 2020-07-10
(Patient Age) : 2 (Gender): Male (Department): Paediatric 2 years old 8 months, fever, mental disorder 4d, 1d "Past History" children admitted to the hospital 4d no obvious causeof fever, body
