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Issue 12/2019 - Low-cost hydrogel materials for efficient and non-destructive islet embedding
Time of Update: 2022-11-14
In addition, this new hydrogel has low cost and easy preparation, which is conducive to expanding production, and has broad prospects in cell therapy, tissue engineering and other medical and health fields.
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Liu Yong's team at Xiangya Hospital of Central South University and others have discovered a potential mechanism to enhance tumor vaccine response
Time of Update: 2022-10-20
On October 13, 2022, Liu Yong's team at Xiangya Hospital of Central South University and Zhang Nu's team at the University of Texas published a research paper entitled "TGF-β-dependent lymphoid tissue residency of stem-like T cells limits response to tumor vaccine" in Nature Communications。 The study revealed a link between TRM and stem cell-like T cells,which inhibits the migration and effector differentiation of stem cell-like T cells, resulting in weakened anti-tumor immunity.
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[PHILIPS once a day] small mesentery giant lymph node hyperplasia
Time of Update: 2022-10-02
CommentsMassive lymph node hyperplasia, also known as Castleman's disease, the cause is unknown; The pathology is divided into type 2, which is common in clinical practice as a transparent vascular type, and a rare plasma cell type.
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What are the characteristics of portable whiteness meters
Time of Update: 2022-09-21
The two electrical signals are amplified separately, and after being processed by the microcontroller, the system functions of automatic zero correction, working whiteboard calibration, and sample testing are realized, and the user can use the instrument very easily to conduct whiteness tests of various samples.
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Cell Stem Cell creates a new human cell type
Time of Update: 2022-09-06
”Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells From left to right: Bradley Balaton, Thi Xuan Ai Pham, Amitesh Panda and Vincent Pasque.
”Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells From left to right: Bradley Balaton, Thi Xuan Ai Pham, Amitesh Panda and Vincent Pasque.
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New discovery: Causes of drug-induced Parkinson's disease
Time of Update: 2022-05-12
Recently, researchers from the Guangzhou Institutes of Biomedicine and Health (GIBH) of the Chinese Academy of Sciences and the Second Affiliated Hospital of Zhejiang University School of Medicine revealed that FNZ induces Parkinson's disease by stimulating the integration of mitochondria and lysosomes (called mitosomes) mechanism of disease .
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Novartis' latest clinical results of SMA gene therapy announced to improve multiple indicators in children
Time of Update: 2022-04-28
Results of a phase 3 clinical trial showed that children with 3 copies of the SMN2 gene and treated prior to symptom onset achieved age-appropriate motor milestones, including standing and walking, without ventilation or feeding tube support, and without severe, Treatment-related adverse events .
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J Clin Oncol: Ibrutinib (ibrutinib) combined with Rituximab (rituximab) in the treatment of indolent mantle cell lymphoma (IMCL-2015
Time of Update: 2022-01-23
Recently, the Journal of Clinical Oncology published the results of a phase II study IMCL-2015 from Spain , which mainly evaluated the use of Ibrutinib (ibrutinib) in combination with Rituximab in patients with clinically indolent mantle cell lymphoma (MCL).
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[JCI Insight] Angel syndrome is expected to improve
Time of Update: 2021-11-04
There is no specific treatment for this disease, but recent studies have shown that restoring the function of the UBE3A gene in neurons is expected to significantly improve the quality of life of patients with Angel Syndrome!
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Cell: Zhou Dawang/Chen Lanfen's research group jointly published a paper revealing the important mechanism of glycogen accumulation and phase separation driving the initiation of liver cancer
Time of Update: 2021-11-03
This work found that early liver tumor cells use the extracted glucose to synthesize glycogen as energy storage, and inhibit the activity of the Hippo signaling pathway through liquid-liquid separation, thereby driving the occurrence and development of tumors .
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When nerve cells are "amazingly" regenerating
Time of Update: 2021-10-22
Therefore, this research team used cell lineage tracing to repeat and test the claims of "astrocytes transdifferentiation into neurons in situ" reported in previous experiments .
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PNAS: Calculating the path of cancer
Time of Update: 2021-10-20
This tool was originally invented to understand the interaction between different mutations in proteins, and now McCandlish and his collaborators are using this tool to understand the complexity of cancer-related gene expression and chromosomal mutations .
They worked with McCandlish to apply his methods to the evolution of gene expression and cancer mutations .
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Cell: Zhang Chunli's research team reveals that strict lineage tracing is critical to the study of nerve cell regeneration
Time of Update: 2021-10-11
At the end of the study, reliable pedigree tracing tests are listed, and it is strongly recommended that these tests be used in all laboratories engaged in nerve cell regeneration research .
Zhang's laboratory has reported some advances in neural stem cell biology, such as the regeneration of mouse brain and spinal cord after injury .
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Canadian researchers develop drugs to treat diabetic retinopathy
Time of Update: 2021-09-06
The antibody designed by the team activates the Frizzled4-LRP5 receptor complex, which successfully stimulates the Wnt signal in the blood-retinal barrier and effectively restores the barrier function .
The antibody restored the mouse's barrier function and corrected the formation of retinal blood vessels .
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Research finds that "variable" immune cells may help develop new crown vaccines
Time of Update: 2021-09-03
Xinhua News Agency, Sydney, August 24 (Reporter Hao Yalin) A new study by an Australian research team found that tissue-resident memory T cells (TRM cells) have different molecular characteristics and behaviors in different tissue environments of the human body.
