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Pang Daiwen's research group of Nankai University: Quantum dot single virus tracing technology cracks the dynamic infection mechanism of viruses
Time of Update: 2023-01-01
This article is the original of Translational Medicine Network, please indicate the source for reprintingWritten by JevinSingle virus tracking (SVT) provides the opportunity to monitor the journey of a single virus in real time and explore the interactions between viruses and cellular structures in living cells, which helps characterize complex infection processes and reveal relevant dynamic mechanisms.
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Stopping repetitive elements contributes to normal brain development and function
Time of Update: 2022-11-14
The study, conducted in laboratory mouse models and human brain organoids, linked the HUSH complex to normal brain development, neuronal personality and connectivity, and mouse behavior.
The study, conducted in laboratory mouse models and human brain organoids, linked the HUSH complex to normal brain development, neuronal personality and connectivity, and mouse behavior.
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【CSCO 2022 Prospect】Application value of ctDNA methylation in early diagnosis of liver cancer and bowel cancer
Time of Update: 2022-10-31
com/s/Ox1vdIZBniFFkD8vwbVe2g Cancer is one of the leading causes of human death.
com/s/Ox1vdIZBniFFkD8vwbVe2g Cancer is one of the leading causes of human death.
com/s/Ox1vdIZBniFFkD8vwbVe2g Cancer is one of the leading causes of human death.
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Neurology: The regulatory role of cognitive reserve markers in children's cognition and cognitive aging: evidence from the 1946 British Birth Cohort
Time of Update: 2022-09-30
The regulatory role of CRI, NART, and APOE in the relationship between cognitive and ACE-III in children was then studied.
The regulatory role of CRI, NART, and APOE in the relationship between cognitive and ACE-III in children was then studied.
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Science Sub-Journal: Inactivated protein complex associated with Parkinson's-like symptoms
Time of Update: 2022-09-08
Article titlePRC2-mediated repression is essential to maintain identity and function of differentiate dopaminergic and serotonergic neurons Johan HolmbergA special protein complex plays a key role in keeping genes off, and its inactivation causes nerve cells to fail to produce enough essential neurotransmitters.
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Preliminary clinical trial results of innovative gene therapy to treat fatal childhood immunodeficiency are positive
Time of Update: 2021-11-01
A few days ago, Rocket Pharmaceuticals announced that its research gene therapy RP-L201 has obtained positive interim data in a phase 1/2 clinical trial for the treatment of leukocyte adhesion deficiency type I (LAD-I) .
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"Cell": Rewriting theories, neuroscientists reveal the mechanism of brain processing speech
Time of Update: 2021-09-04
▲Directly record signals through electrodes and give stimuli to discover parallel pathways for voice information processing (picture source: reference [1])In another experiment, the researchers used a weak electric current to stimulate the patient's auditory cortex .
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Science Advances reveals the mechanism behind alcohol addiction
Time of Update: 2021-08-27
Researchers have investigated the mechanisms behind addictive behavior, which refers to continuing to use alcohol even if it has negative consequences.
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Cell Reports reveal a new mechanism of influenza virus-induced bacterial co-infection
Time of Update: 2021-08-11
The study found that the host protein CyclophilinA (CypA) is critical to the infection of group A streptococci (GAS), and the induction of CypA expression is a new way for influenza A virus (IAV) to promote bacterial co-infection, suggesting that CypA is a secondary A promising therapeutic target for sexual bacterial infections .
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Why not skip RNA purification for gene expression analysis
Time of Update: 2021-08-10
To this end, Bio-Rad recently launched a new rapid cell lysis kit that allows researchers to obtain RT-qPCR data directly from cultured cells without the need for separate RNA purification .
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Cell publication reveals the secret behind the threat of non-alcoholic liver disease
Time of Update: 2021-07-31
" Loss of identity can lead to dysfunctionResearchers use comparative genomics to analyze the mechanisms that control the development and special functions of the most abundant cell types in the liver.
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This most dangerous blood cancer is expected to be cured
Time of Update: 2021-07-20
Recently, researchers from the Spanish Center for Genome Regulation (CRG) and the European Molecular Biology Laboratory (EMBL) published an article titled "Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell " in " Nature Communications " The article "transcriptomics" brings a new method of treating leukemia based on single-cell multi-omics, laying the foundation for people to find drugs to eliminate cancer from the source .
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Cell Journal: Exercise only knows the advantages but not the disadvantages
Time of Update: 2021-04-13
However, in the third phase of the trial , the study found that most of the volunteers had insulin resistance similar to those of diabetic patients.
Diabetes Further, in addition, with the first phase to the first phase trial test compared to samples collected during the volunteers mitochondrial respiration average decrease of 40%.
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Nat Med: Joint cartilage is renewable
Time of Update: 2021-03-02
Studies have reported that MF stimulates fibrous cartilage formation in adult mice, but little is known about the effects of the technique on bone stem cells (SSC) and how to stimulate tissue regeneration.
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Light Microscopy: Overview and Basic Methods
Time of Update: 2020-12-29
lectin histochemistry and cytochemistry can provide an extraordinarily sensitive detection system for changes in glycosylation and carbohydrate expression that may occur during embryogenesis, growth, and disease.
lectin histochemistry or cytochemistry can reveal subtle alterations in glycosylation between otherwise indistinguishable cells.
