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Nat Commun: Using DNA barcoding technology may reveal the ability of cancer cells to evade attacks by the host body's immune system
Time of Update: 2023-01-05
Although immune checkpoint inhibitors can effectively reactivate tumor immunity in some cancer types, many other solid tumors, including breast cancer, may be largely unresponsive, and understanding
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On the cover of Cell
Time of Update: 2022-05-21
▲ Schematic diagram of spindle-shaped virus and other forms of viruses in a near-boiling acidic volcanic hydrothermal environment (Image source: Egelman lab at UVA) Recently, a team led by the University of Virginia and the Pasteur Institute in France published a paper The evolutionary path of spindle virus was revealed in .
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Front Oncol: Differences in clinical characteristics and clinical prognosis of patients with non-metastatic non-clear cell renal cell carcinoma (non-ccRCC
Time of Update: 2022-01-23
Non-clear cell renal cell carcinoma (non-ccRCC) includes histologically and molecularly distinct subtypes, such as papillary, chromophobe, collecting duct, and sarcomatoid RCC, with an incidence of 20% to 25% .
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Cell blockbuster: discovering new targets for cancer vaccines
Time of Update: 2021-10-10
On September 16, 2021, the MIT research team published a research paper titled: Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors in the top international academic journal Cell .
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Dev Cell: Dying cells protect their neighbors to maintain tissue integrity
Time of Update: 2021-08-02
Scientists from the Pasteur Institute and the French National Center for Scientific Research today revealed a new process that allows eliminated cells to temporarily protect their neighboring cells from death, thereby maintaining tissue integrity .
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Gaofu team proposes a new strategy for safe and effective Zika vaccine
Time of Update: 2021-07-29
Antigenic rational design based on the structure of ADE antibody targeting FL epitope The results showed that, MUTB / C vaccine immunization can generate an immune response of clearing , completely protected mice against challenge Zika virus , in all target tissues are infected with the virus undetectable viral load .
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A system OFHIT2 that can simultaneously implement drug-induced genome editing and transcription activation
Time of Update: 2020-08-11
the establishment of these systems provides a powerful technical tool for more flexible, diverse, accurate and controlled editing and regulation of gene functions to achieve higher space-time "resolution" in the analysis of key biological events, and thus provides more potential for clinical applications by combining the advantages of small molecule drugs and gene therapy.
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Research and development of daily Sanofi CD38 antibody combination therapy reaches phase 3 clinical end
Time of Update: 2020-05-13
Roche Integratin Antibody UCIII Data are released at the same time; cord blood stem cell therapy omidubicel reaches the end of Phase 3 clinical trial; Fosun Pharma's pharmaceutical injection sodium
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JACS: biorthogonal reaction of isonitrile chloroxime
Time of Update: 2019-12-07
Biorthogonal reaction refers to the chemical reaction that can be carried out in living cells or tissues without interfering with biological biochemical reaction It was proposed by Carolyn R bertozzi
