Nat Commun: Using DNA barcoding technology may reveal the ability of cancer cells to evade attacks by the host body's immune system
Time of Update: 2023-01-05
Although immune checkpoint inhibitors can effectively reactivate tumor immunity in some cancer types, many other solid tumors, including breast cancer, may be largely unresponsive, and understanding
On the cover of Cell
Time of Update: 2022-05-21
▲ Schematic diagram of spindle-shaped virus and other forms of viruses in a near-boiling acidic volcanic hydrothermal environment (Image source: Egelman lab at UVA) Recently, a team led by the University of Virginia and the Pasteur Institute in France published a paper The evolutionary path of spindle virus was revealed in .
Front Oncol: Differences in clinical characteristics and clinical prognosis of patients with non-metastatic non-clear cell renal cell carcinoma (non-ccRCC
Time of Update: 2022-01-23
Non-clear cell renal cell carcinoma (non-ccRCC) includes histologically and molecularly distinct subtypes, such as papillary, chromophobe, collecting duct, and sarcomatoid RCC, with an incidence of 20% to 25% .
Cell blockbuster: discovering new targets for cancer vaccines
Time of Update: 2021-10-10
On September 16, 2021, the MIT research team published a research paper titled: Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors in the top international academic journal Cell .
Dev Cell: Dying cells protect their neighbors to maintain tissue integrity
Time of Update: 2021-08-02
Scientists from the Pasteur Institute and the French National Center for Scientific Research today revealed a new process that allows eliminated cells to temporarily protect their neighboring cells from death, thereby maintaining tissue integrity .
Gaofu team proposes a new strategy for safe and effective Zika vaccine
Time of Update: 2021-07-29
Antigenic rational design based on the structure of ADE antibody targeting FL epitope The results showed that, MUTB / C vaccine immunization can generate an immune response of clearing , completely protected mice against challenge Zika virus , in all target tissues are infected with the virus undetectable viral load .
A system OFHIT2 that can simultaneously implement drug-induced genome editing and transcription activation
Time of Update: 2020-08-11
the establishment of these systems provides a powerful technical tool for more flexible, diverse, accurate and controlled editing and regulation of gene functions to achieve higher space-time "resolution" in the analysis of key biological events, and thus provides more potential for clinical applications by combining the advantages of small molecule drugs and gene therapy.
Research and development of daily Sanofi CD38 antibody combination therapy reaches phase 3 clinical end
Time of Update: 2020-05-13
Roche Integratin Antibody UCIII Data are released at the same time; cord blood stem cell therapy omidubicel reaches the end of Phase 3 clinical trial; Fosun Pharma's pharmaceutical injection sodium
JACS: biorthogonal reaction of isonitrile chloroxime
Time of Update: 2019-12-07
Biorthogonal reaction refers to the chemical reaction that can be carried out in living cells or tissues without interfering with biological biochemical reaction It was proposed by Carolyn R bertozzi