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Cancer breakthrough: Predict within hours whether a cancer patient will survive chemotherapy
Time of Update: 2023-02-01
"Early response evaluation by single cell signaling profiling in acute myeloid leukemia Benedicte Sjo TislevollResearchers at the University of Bergen in Norway have discovered a new method that can predict within hours whether certain cancer patients will survive chemotherapy.
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Nature sub-issue: Analysis of the working mechanism of the new CRISPR antiviral system in bacteria
Time of Update: 2023-01-06
On October 27, 2022, in a new study published in Nature Microbiology, Zhang Heng's team from Tianjin Medical University and the Wuhan Institute of Virology, Chinese Academy of Sciences By analyzing the cryo-EM structure of Cas7-11 complexes in different states, Deng Zengqin's team used a large number of biochemical experiments to elucidate the mechanism of Cas7-11 processing precursor CRISPR RNA (pre-crRNA) and identifying and cleavaging target RNA.
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Nature sub-issue: Analysis of the working mechanism of the new CRISPR antiviral system in bacteria
Time of Update: 2023-01-06
On October 27, 2022, in a new study published in Nature Microbiology, Zhang Heng's team from Tianjin Medical University and the Wuhan Institute of Virology, Chinese Academy of Sciences By analyzing the cryo-EM structure of Cas7-11 complexes in different states, Deng Zengqin's team used a large number of biochemical experiments to elucidate the mechanism of Cas7-11 processing precursor CRISPR RNA (pre-crRNA) and identifying and cleavaging target RNA.
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PNAS: breaks through the blood-brain barrier, targets pathogenic RNA, treats ALS and dementia
Time of Update: 2023-01-05
Written byWang Cong EditorWang Duoyu TypesettingWater WritingAmyotrophic lateral sclerosis (ALS), also known as ALS, is one of the five terminal diseases recognized by the World Health Organization (W
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A revolutionary way to observe cell trafficking
Time of Update: 2022-11-01
Enrica Bordignon explains: "When two nanobodies bind to a transporter, we can measure the distance between two magnetic probes in the cell using the EPR method.
Enrica Bordignon explains: "When two nanobodies bind to a transporter, we can measure the distance between two magnetic probes in the cell using the EPR method.
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[PHILIPS 1 case per day] 1 case of cervical vertebral neurofibroma
Time of Update: 2022-09-14
Fig. 1 shows that the soft tissue window artery stage after cross-section CT enhancement shows mild strengthening of the flaky patches scattered within the cervical 6 spinous lesions; Fig. 2 is a CT s
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Nature: LAG-3, the next outlet
Time of Update: 2022-06-01
At the LAG3 Targeted Drug Development Summit held in January this year, Paul Moore from MacroGenics said that the PD-1×LAG-3 bispecific antibody Tebotelimab can simultaneously block the growth of a single T cell.
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Functional cure for hepatitis B
Time of Update: 2022-01-26
References:[1] VBI Vaccines Announces Dosing of First Patient in Second Phase 2 Study in Chronic Hepatitis B Patients as Part of Expansion of Clinical Collaboration With Brii Bio.
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Cell sub-journal: Decoding epigenetic mechanisms of parent-specific gene activation
Time of Update: 2022-01-23
However, for about 1% of our genes, only the one inherited from the father or mother is active, and the other gene is inactive, a phenomenon known as genomic imprinting .
"There are almost three known epigenetic mechanisms that we can use to explain gene expression specific to all parents," Andergassen said .
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Does wolfberry really beautify your skin
Time of Update: 2021-12-29
Women often eat wolfberry to have a certain beauty and anti-aging effects .
Among them, natural anthocyanins with anti-oxidant function can effectively remove free radicals in the human body and delay the aging of the human body .
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Treating a variety of neurological diseases about 2.6 billion US dollars to help develop selective GPCR agonists
Time of Update: 2021-12-04
Recently, Neurocrine Biosciences and Sosei Heptares announced a strategic cooperation and licensing agreement to jointly develop new selective muscarinic receptor agonists for the treatment of schizophrenia, dementia and other neurological diseases .
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New mechanism of immune and neural interaction aggravating asthma revealed
Time of Update: 2021-11-11
In 2020, Academician Song Erwei and Researcher Su Shicheng's Nature research article identified the first DNA sensor CCDC25 located in the plasma membrane of the cell, and clarified its mechanism of mediating the extracellular DNA network of neutrophils to promote tumor metastasis .
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Clinical Lung Cancer: The role of HER2 gene changes in EGFR mutant non-small cell lung cancer (NSCLC
Time of Update: 2021-11-02
With the identification of various driver gene mutations, the treatment mode of advanced non-small cell lung cancer ( NSCLC ) has shifted from chemotherapy-based treatment to molecular targeted therapy-based treatment .
Breast cancerGastric Cancer FDAA total of 12,946 NSCLC patients were included in this study with analyzable EGFR and HER2 NGS data .
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This cytokine can increase the production of "beige fat
Time of Update: 2021-08-14
On August 5th, Zhonghan Yang of Sun Yat-sen University in Guangzhou, China, and his colleagues published a new study in the open-access journal PLOS Biology , showing that immune signals promote the production of energy-burning “beige fat” .
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Express treatment of bladder cancer, "first-in-class" antibody-conjugated drugs expand indications
Time of Update: 2021-08-10
▎The content team editor of WuXi AppTec today, Seagen and Astellas jointly announced that the US FDA has approved the company’s antibody-conjugated drug (ADC) Padcev (enfortumab vedotin-ejfv) for extended indications for the treatment of previous Patients with locally advanced or metastatic urothelial cancer who have received at least one pre-treatment, but are not suitable for receiving cisplatin-containing chemotherapy .
