The IRd total oral regimen assists in continuous treatment and the analysis of elderly MM cases
Time of Update: 2022-09-15
Member of hematology branch of Shandong Medical AssociationDeputy Leader of the Transplantation Group of the Hematology Branch of Shandong Medical AssociationMember of the Standing Committee of the Hematology Branch of Shandong Medical Doctor AssociationThe patient was an elderly patient with frail MM with anemia, colon, and ovarian disease, and partial remission (PR) was achieved after induction of therapy from dexamethasone to IRd regimen.
Cell: Negative health effects of obesity are not in excess fat but in loss of function
Time of Update: 2022-03-04
In a review-type article titled "Adipose tissue plasticity in health and disease" published in the February 3 , 2022 issue of Cell , the researchers argue that the negative health effects of obesity stem from more than just Too much fat also stems from its reduced ability to respond to change, or in other words, its reduced plasticity .
Fundamental principles of glial transdifferentiation: NeuroD1 cannot mediate microglia-neuron reprogramming
Time of Update: 2022-01-26
A joint research by researchers from Peng Bo's research group from the Translational Institute of Brain Science, Fudan University, Mao Ying's research group from Huashan Hospital Affiliated to Fudan University, and Yuan Tifei's research group from Shanghai Mental Health Center uses live-cell imaging, rigorous lineage tracing, and pharmacology.
75% objective relief
Time of Update: 2022-01-11
On December 6, 2021, Adicet Bio announced that a dose-escalation phase 1 clinical trial of the allogeneic, "ready-to-use" CD20 targeting CAR γδ-T cell therapy ADI-001 has obtained positive interim data .
Nature small molecule metabolites also "cross-border
Time of Update: 2021-12-06
B cell regulation of anti-tumor immune response.
Reprinting instructions [Original Articles] BioArt original articles, personal forwarding and sharing are welcome, reprinting without permission is prohibited, all published works The copyright is owned by BioArtImmunologic research 57, 115-124, doi:10.
Using single-cell sequencing to analyze the developmental process of human embryonic spinal cord
Time of Update: 2021-10-22
Dai Jianwu's research team and Professor Hu Yali's team from Nanjing Gulou Hospital used single-cell transcriptome technology for the first time to analyze the human embryonic spinal cord during early and second pregnancy .
Cell’s latest discovery: ruptured cell nucleus promotes cancer cell invasion
Time of Update: 2021-09-29
In the breast ducts, the crowding of cells causes the nuclear membrane to rupture, resulting in TREX1-dependent DNA damage, which promotes the progression of carcinoma in situ to the invasive stage .
The first molecular map describing the development of the human cerebellum
Time of Update: 2021-07-31
The first molecular map describing the development of the human cerebellum The first to describe the creation of a molecular map of human cerebellar development The first to describ
CELL: The local intrinsic immunity of severely ill patients with SARS-CoV-2 infection is impaired
Time of Update: 2021-07-30
In order to promote effective prevention of COVID-19 And treatment, distinguishing host protection mechanisms that support rapid virus clearance and limit disease from protection mechanisms that lead to serious and fatal results is crucial for preventionAt present, we still do not fully understand which cells are the main targets of SARS-CoV-2 and how the infection affects respiratory epithelial cells .
One thing drops one thing
Time of Update: 2021-07-25
Mtp53 inhibits cell-autonomous and non-cell signaling by interfering with the function of the cytoplasmic DNA sensing mechanism cGAS-STING-TBK1-IRF3, thereby promoting cancer cell growth and evading immune surveillance.
. Restoring TBK1 signal can bypass mtp53, restore immune cell function, activate immune surveillance, and eradicate cancer cells .
An innovative NRF2 nanomodulator induces iron death of lung cancer and induces immune-stimulated tumor microenvironment
Time of Update: 2021-06-22
This dual-functional nanomedicine establishes an effective strategy for synergistically inducing the death of iron chain cancer cells and reprogramming the immunosuppressive microenvironment, which highlights the potential of ZVI-NP as an advanced comprehensive anti-cancer strategy .
Cell: Reveals the antiviral immune response points of targeted tumors in triple-negative breast cancer
Time of Update: 2021-03-10
'Our study reveals a new way to activate the body's inflammatory response by specifically targeting cancer cells,' said Dr. Elizabeth Bowling, .
PNAS: Stem cell research suggests new ways to restore hearing
Time of Update: 2020-06-17
, June 6, 2020 /PRNewswire / -- To hear a person's cry, you need a protein called Yap As part of the Yap/Tead complex, this important protein sends signals to the hearing organs to the correct size
Scientists are expected to develop new anti-cancer therapies that have no damaging effect on healthy cells
Time of Update: 2020-06-02
Medicines Network, Aug 13 (Xinhua) -- In a study published in the international journal Journal of Bio Chemicalry, scientists from Oregon State University are looking to develop a new type of effect
Japan approved the world's first iPS cell clinical trial in the treatment of spinal cord injury
Time of Update: 2019-02-19
Japan's Ministry of health, labor and welfare approved the world's first clinical trial on the use of induced pluripotent stem cells (iPS cells) in the treatment of spinal cord injury Monday If all go