5 common medication misunderstandings you must know before targeted therapy
Time of Update: 2022-11-25
 Osimertinib in Untreated EGFR-Mutated Advanced Non–Small-Cell Lung Cancer | NEJM class="weui-dialog__ft"> UnCancel Allow： ， 。 ， ， In recent years, with the emergence of targeted therapy drugs, the treatment options of cancer patients are gradually increasing.
Notice of the 5th CBIC Cell Bio-Industry Conference
Time of Update: 2022-08-30
Agenda planning Topic 1: Cell therapy innovation and application Topic 2: Clinical application and industrial transformation of stem cells Topic 3: 3D cell culture and clinical application of organoids Topic 4: Single Cell Multiomics and New Applications of Cellular Exosomes Topic 5: Clinical R&D and New Applications of Novel Antibody Drugs Topic 6: Upstream and Downstream Process Innovation Technology of Novel Antibody DrugsThe 5th CBIC Cell Bio-Industry Conference The 3rd China Biomedical Innovation Cooperation ConferenceConference details
Cell Rep: Reconstructing real-time gene expression patterns from single-cell RNAseq datasets
Time of Update: 2022-08-19
article titleA guiding role of the Arabidopsis circadian clock in cell differentiation revealed by time-series single-cell RNA sequencing Figure: In the proposed model, BES1 rearranges the circadian clock by repressing LHY expression in meristem cells, resulting in a rephase and reconstruction of the clock with dynamic changes in the expression of clock genes .
The regulatory role of SRSF2 in skeletal muscle embryonic development
Time of Update: 2022-05-12
On April 23, 2022, the international academic journal Advanced Science published a collaboration titled "Single-Cell RNA Sequencing Reveals Heterogeneity of Myf5-Derived Cells and Altered Myogenic Fate in the The latest research results of Absence of SRSF2" .
Innovative therapy reverses the symptoms of Alzheimer's disease in animals and stimulates cells to "clean up garbage
Time of Update: 2021-05-09
"On April 22, researchers at the Albert Einstein College of Medicine in New York, the United States, announced the design of an experimental drug designed to stimulate a special cell "garbage cleanup" mechanism, which can be used in animal models.
Revealing the mystery of liver regeneration, two Chinese scholars made important breakthroughs in two "Sciences
Time of Update: 2021-04-27
▲In the profile of liver lobules, a type of hepatocytes expressing specific genes are marked with fluorescent markers (picture source: reference ) Although the methods used are different, the two research teams have found that whether it is to maintain liver stability under normal conditions The state is to repair and regenerate after injury.
Neuron | Song Hongjun's team reveals the basic laws of the development and formation of the hypothalamic nucleus
Time of Update: 2021-03-25
The author was surprised to find that the glutamatergic ventromedial nucleus neurons and the gamma-aminobutyric acid nodular nucleus neurons originated from the same precursor cell area in the embryonic stage, and named them pVMH (progenitor domain of ventromedial hypothalamus).
Cell Death Differ: GLI1 mediates the occurrence and development of chondrosarcoma through mTOR/S6K1 signaling cascade
Time of Update: 2021-03-20
Simultaneous inhibition of MVP and GLI1 significantly inhibits the growth of CSIn this study, the researchers confirmed that GLI1 participates in the SMO-independent signaling pathway in CS cells.
1038/s41418-021-00749-4">Constitutive GLI1 expression in chondrosarcoma is regulated by major vault protein via mTOR/S6K1 signaling cascade .
Chinese scientists draw the world's first atlas of human cells
Time of Update: 2021-03-06
The team conducted Microwell-seq high-volume single-cell sequencing analysis of 60 human tissue samples and 7 cell culture samples, systematically mapping human cells spanning two periods of embryo and adulthood, covering eight systems.
Several articles focus on new achievements by scientists in the field of rare diseases
Time of Update: 2021-01-29
doi:10.1002/jimd.12345 Recently, scientists at the University of Exeter have found a way to "save" cell gene mutations for possible fatal diseases such as mitochondrials in rare children The new treatment paves the way; the team, published in the journal Journal of Inherited Metabolic Disease, used a new drug being developed by the University of Exeter that provides alternative fuels for mitochondrials through "metabolic reprogramming." produces a small amount of metabolic energy in the form of hydrogen sulfide.
Cells: The acute stage of neocyto pneumonia has a greater T-cell effect than antibodies
Time of Update: 2020-12-05
17 (Xinhua Zhang Jiaxin) 16, the United States "Cell" magazine published the latest paper of the La Jolla Institute of Immunology, said that in the acute stage of infection with coronary pneumonia, T-cell-mediated immune response plays an important role in the control of the virus and reduce the severity of the disease.
Cell Res: Peng Xiaozhong/Deng Hongkui has proposed a new strategy for treating new coronary pneumonia, targeting macrophages
Time of Update: 2020-10-10
September 30, 2020, Peng Xiaozhong of the Concord Medical College of Beijing and Deng Hongkui of Peking University published a research paper entitled "Effective treatment of SARS-CoV-2-infected rhesus macaques by attenuating inflammation" published online by Cell Research, which demonstrated that the small molecule SSK1 effectively treats COVID-19 pneumonia by controlling macrophage immersion.
The loss of NK cell subgroup secretion growth factors can result in limited embryo growth
Time of Update: 2020-08-16
Professor Wei Haiming and Professor Tian Zhigang of the Institute of Immunology of the Chinese University of Science and Technology worked together to find that a large number of NK cell subgroups exist locally in early pregnancy metamorphosis tissue spotting in humans and mice to promote the development of embryos by secreting growth factors.