NEJM: The third-generation immune checkpoint comes into play: LAG-3+PD-1, doubles progression-free survival in advanced cancer
Time of Update: 2022-01-23
In this phase II/III double-blind randomized controlled clinical trial, a total of 714 patients with previously untreated advanced melanoma were randomized 1:1 to receive either Relatlimab + Nivolumab combination therapy or Nivolumab monotherapy .
ODSR: Comparison of colchicine in the treatment of acute gout
Time of Update: 2021-11-12
The number of people who report successful treatment (50% or more pain reduction) within 32 to 36 hours, use low-dose autumn The number of people with narcissus was slightly higher than that of placebo Low-quality evidence from two trials (124 participants) (downgraded due to imprecision and prejudice) suggests that high-dose colchicine may improve symptoms compared to placebo, but increase the risk of harm .
Last issue of Energy Revised Low Sulfur Fuel Oil Futures Rules
Time of Update: 2021-09-10
Regarding the revision of the low-sulfur fuel oil contract, the three quality standards of density, styrene and phenol in the delivery quality were mainly adjusted .
J Clin Oncol: Phase III SORCE . Soraphinist cannot be used as a postoperative ancillary treatment for primary kidney cancer with a medium to high risk of recurrence
Time of Update: 2020-10-28
SORCE is an international, randomized, double-blind three-arm trial that evaluates the effectiveness of Solaffini's complementary therapy in patients with primary renal cell carcinoma (RCC) who are at a medium to high risk of recurrence after surgical excision.
Clin Trans Gastroenterology: There is a generally significant increase in lipase in patients with new coronary pneumonia
Time of Update: 2020-08-21
elevated lipase may indicate pancreatic damage, and 18% of patients admitted to severe COVID-19 in China have recently reported elevated lipase levels in patients with new crowns, and have been shown to have elevated levels of ACE2 receptors in the pancreas higher than respiratory epithelial cells.