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Principles of Western blotting experiments, sample preparation and specific experimental procedures
Time of Update: 2022-09-14
Proteins from a variety of sample sources can be analyzed by Western blot analysis, such as mammalian, bacterial cell cultures, or samples from clinical tissues, each requiring a different treatment to produce high-quality proteins for end use.
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Zhu Yingfang's research group published a review paper on plant stress responses in Trends in Plant Science
Time of Update: 2022-01-23
Zhu Yingfang from Henan University were invited to jointly write a review of mass spectrometry research technology related to plant stress response research.
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OMCL: Increased serum fetuin-B levels in women with metabolic syndrome are associated with increased oxidative stress
Time of Update: 2021-10-20
Bioinformatics analysis shows that most of the core genes related to fetuin B are involved in cholesterol metabolism and lipolysis .
Serum Fetuin-B Levels Are Elevated in Women with Metabolic Syndrome and Associated with Increased Oxidative Stress .
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Neurology-The latest cerebrospinal fluid detection technology may predict Lewy body dementia
Time of Update: 2021-08-03
Current evidence shows that real-time quaking-induced conversion (RT-QuIC, RT-QuIC) can accurately detect misfolded α-synapses in the CSF of patients with Parkinson’s disease or Lewy body dementia (DLB) Protein (α-syn), its overall sensitivity is 95%, and its specificity is 98% .
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Cancer Cell: The molecular mechanism of key protein-mediated tumor immune tolerance
Time of Update: 2021-04-18
Therefore, targeting the STC1 protein on the surface of tumor cells can help reduce tumor immune evasion and resistance to immunotherapy.
023 Original source: Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance.
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Jimin Trust's New Coronary Neutralizing Antibody Obtains Clinical Approval from U.S. FDA
Time of Update: 2021-04-14
One of the key steps for the new coronavirus to infect human cells is the receptor binding domain (RBD) of the S1 subunit of the virus surface spike protein (S protein) and the angiotensin II converting enzyme 2 (ACE2) on the surface of human cells.
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Detection of Sequence-Specific Protein-DNA Interactions by the DNA-Footprinting Technique
Time of Update: 2021-01-05
The initiation of transcription of eukaryotic genes by RNA polymerases is controlled by complex interactions between nonhistone proteins and specific regulatory DNA sequences (promoters and enhancer
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Assays for RING Family Ubiquitin Ligases
Time of Update: 2020-11-25
Many eukaryotic proteins are regulated by the covalent attachment of ubiquitin or polyubiquitin chains.
RING finger-based ubiquitination utilizes RING-containing protein subunits, or proteins with intrinsic RING domains, to catalyze the formation of polyubiquitin chains.