Guohong Hu, a researcher at the Institute of Nutrition and Health, was invited to discuss the frontiers of tumor metastasis research in the journal Cancer Cell
Time of Update: 2022-10-13
With the diversification and precision of tumor treatment strategies, the prognosis of tumor patients has been effectively improved, but distal organ metastasis is still the most important cause of d
Important progress has been made in the epigenetic regulation of corn kernel development in Huazhong Agricultural University
Time of Update: 2022-09-10
(Editor Li Chuang) Recently, the corn team of Huazhong Agricultural University revealed the biological function and related mechanism of DNA demethylase affecting the expression of genes related to grain development, providing important theoretical support for the genetic improvement of corn grain yield .
These two inherited gene mutations increase the risk of 7 types of cancer
Time of Update: 2022-09-09
They had 14 different types of cancer (biliary tract, breast, cervical, colorectal, endometrial, esophageal, stomach, liver, lung, lymphoma, ovarian, pancreatic, prostate and kidney cancers) ) or one or more of them .
Chinese medicine reverses multidrug resistance in cancer and its mechanism
Time of Update: 2022-04-24
These mechanisms play a key role in the development of several MDR-reversing agents: aberrant expression of cell membrane transporters, adaptation of cancer cells to the microenvironment, regulation of hypoxia, DNA repair, damage and reduction of apoptosis, enhancement of EMT processes , the presence of cancer stem cells (CSCs) and aberrant activation of key signaling pathways .
New method for non-destructive DNA extraction
Time of Update: 2022-04-18
"Ancient mitochondrial genomes recovered from small vertebrate bones through minimally destructive DNA extraction: Phylogeography of the New Zealand gecko genus Hoplodactylus
Professor Hu Zhongjie: Application of New Molecular Diagnosis Technology in Bacteriological Diagnosis of Cirrhosis and Ascites
Time of Update: 2021-12-04
Yimaitong is fortunate to invite Professor Hu Zhongjie from Beijing You'an Hospital, Capital Medical University, to share the application of new molecular diagnostic technology in the bacteriological diagnosis of liver cirrhosis and ascites .
Under the froth of the "Innovative Era", the "involution" of biological products is becoming fierce
Time of Update: 2021-12-02
This article focuses on the analysis of the clinical trial information of biological products registered in the "Annual Report on the Status of Clinical Trials of New Drug Registration in China (2020)" .
PLOS Medicine: Using cfDNA to distinguish benign tumors from malignant tumors
Time of Update: 2021-09-12
Co-corresponding author Aadel Chaudhuri of the Settman Cancer Center of the University of Washington said: "Using the combination of ultra-low-depth whole-genome sequencing and free DNA fragment screening, we can specifically and sensitively distinguish MPNST patients from those with benign lesions.
Cheng Zhukuan's research group has made new progress in improving the frequency of recombination
Time of Update: 2021-08-14
However, the number of chromosomal crossovers in most organisms is maintained at a very low level, making it difficult for genetic material to fully communicate and recombine, and lead to the occurrence of chain duplication, which greatly affects the efficiency of species genetic improvement .
Nature publication reveals the genetic mechanism of hypertension
Time of Update: 2021-06-06
Cis-eQTL analysis of human kidney and genetic variants identified in BP-GWASSubsequently, the researchers explored the relationship between kidney gene alternative splicing and DNA methylation and blood pressure.
About 15% of GWAS signals may be driven by molecular regulation (expression, alternative splicing or DNA methylation) of kidney genes at different levels.
Time of Update: 2021-05-22
(Beihai Kangcheng) announced that it has reached a strategic cooperation with LogicBio Therapeutics (LogicBio, NSDQ: LOGC) and signed a licensing and licensing agreement to obtain the use of the first adeno-associated virus produced on the LogicBio sAAVy technology platform ( AAV) sL65 capsid, the global authorization for the development, production and commercialization of gene therapy candidates for Fabry and Pompe, as well as the option of two additional indications.
MADS and More: Transcription Factors That Shape the Plant
Time of Update: 2021-03-15
Here we review typical features such as domain structure,DNA binding, and protein interactions of TFs from some families that have contributed to the development and evolution of plant-specific structures in especially important ways.
The study used "gene scissors" to deal with antibiotic resistance
Time of Update: 2021-03-14
U.S. researchers recently reported that they have used "gene scissors" to develop a new system that can identify genes that specific antibiotics can target to pathogenic bacteria, promising to be used to improve the effectiveness of existing antibiotics or to develop new ones.
Scientists used CRISPR technology to improve bananas
Time of Update: 2021-03-14
Banana stripe virus is a widely distributed virus that causes disease by inserting its own DNA into the banana B genome, which can eventually lead to crop death.
For example, when bananas are threatened by drought or high temperatures, banana stripe virus DNA produces functional viral particles that eventually cause disease symptoms.
Identification of HR-Inducing cDNAs from Plant Pathogens via a Gateway-Compatible Binary Potato Virus X-Expression Vector
Time of Update: 2021-03-13
Identification of pathogen effectors that elicit a hypersensitive response (HR) in resistant plant hosts is essential to study disease resistance. In this method, it is described how to generate a c