Genetic mutations have been linked to learning defects in "ignorant" mice
Time of Update: 2022-09-09
A new study published in the Proceedings of the National Academy of Sciences (PNAS) by researchers at the University of Texas Southwest reports that a single mutation in the gene Kc3, which codes for the potassium channels of neurons, causes learning disabilities in mice.
Cell's new discovery solves a century-old mystery
Time of Update: 2022-04-16
A team led by researchers at Utah State University has discovered a molecule produced by male parasites called schistosomes that promotes sexual maturation in females of these species .
They soon discovered that a gene called gli1 appeared to play a key role in promoting female sexual maturity in males .
Stem cells rebuild the ovarian environment that promotes mature eggs
Time of Update: 2021-10-01
Researchers led by Kyushu University in Japan have successfully used mouse stem cells to reconstruct structures in the ovarian environment that are essential for the production of mature egg cells .
Deletion of EMBO J︱ neuron Miro1 protein disrupts mitochondrial autophagy and over-activates the integrated stress response
Time of Update: 2021-09-30
, EMBO J 2021; 40: e100715) Figure 5 Work summary diagram: Miro1 deletion leads to long-term destruction of mitochondrial homeostasis and mitochondrial fusion, mitochondrial remodeling and integrated stress response ( ISR) continues to be activated .
AstraZeneca announces Phase 3 data for new crown vaccine
Time of Update: 2021-04-20
On March 25, local time, AstraZeneca's official website announced that the preliminary analysis results of the phase III clinical trial of the new crown vaccine AZD1222 were consistent with the interim analysis results announced on March 22.
Fast and Easy Method for Construction of Plasmid Vectors Using Modified Quick-Change Mutagenesis
Time of Update: 2021-01-31
Plasmid vector construction is an essential step for molecular microbiology yet often a time-consuming process.
Manipulation of the fungal genome to express genes to activate secondary metabolite production often requires creation of plasmid constructs in a reiterative fashion.
Gene Essentiality Testing in Mycobacterium smegmatis Using Specialized Transduction
Time of Update: 2021-01-31
Conditional expression–specialized transduction essentiality test (CESTET) is a genetic tool used to determine essentiality of individual genes inMycobacterium smegmatis .
Furthermore, effects of loss of essential gene function can then be studied by growing the transductants in medium depleted of acetamide.
Studying Translation in Arabidopsis Chloroplasts
Time of Update: 2020-11-17
On the contrary, translation regulatory processes based on selection of translatable mRNA by either nucleus-encoded activation factors or sensors of the assembly status of chloroplast multiprotein complexes have been reported.
Floral Dip: Agrobacterium-Mediated Germ Line Transformation
Time of Update: 2020-11-12
Many researchers use the flowering plantArabidopsis thaliana to study gene function and basic plant biology.
Another very useful feature ofArabidopsis is that it is extremely simple to transform genetically.
The ability to insert genes of interest stably into a given plant is essential to understand and verify gene function.
Study found hundreds of genes that are prone to oncogenes
Time of Update: 2020-06-01
Using genetic expression data from multiple public sources, Dr Xingyi Guo, Dr Zhishan Chen, and colleagues systematically evaluated 294 GWAS-related variants for six types of cancer - colorectal cance