Shanghai Jiaotong University Li Dan's group and collaborators discovered and characterized a novel pathological protein fiber aggregate formed by TMEM106B in the human brain
Time of Update: 2022-05-10
In this study, researchers discovered a previously unknown cluster of novel pathological proteins extracted directly from the brain tissue of a Parkinson's disease dementia (PDD) patient with dementia and two elderly healthy controls.
Optimal insulin treatment plan to help Chinese diabetic patients effectively control their sugar
Time of Update: 2022-04-28
;Due to the dietary structure and ethnic characteristics, Chinese patients with type 2 diabetes are characterized by postprandial hyperglycemia, and the treatment strategy should take into account FPG and PPG; degludec aspart is a new generation of basal insulin combined with mealtime insulin.
Diabetes: Changes in sleep disturbance, energy intake, and body synthesis during weight loss in a weight loss trial
Time of Update: 2022-04-20
OBJECTIVE: To investigate the relationship between sleep disturbance and changes in body weight and body composition, and the mediating role of changes in appetite and food cravings in the 2-year Weight Loss Diet Intervention Trial, which included 810 overweight or obese individuals assessed for baseline sleep disturbance Individuals, who were randomly assigned to one of four diets, varied in their macronutrient content .
JCSM: The characteristics of body composition changes in elderly patients with type 2 diabetes and prediabetes compared with controls
Time of Update: 2022-03-05
The purpose of this study was to compare local body composition (by dual energy X-ray absorptiometry (DXA)), muscle and subcutaneous adipose tissue (SAT) thickness (by ultrasound) in older adults with T2D or prediabetes with normoglycemic controls ) and ultrasound-based muscle texture characterization .
Painful gallstone removal
Time of Update: 2022-02-21
Case review: strange abdominal pain This is a patient with gallstones and cholecystitis who has just been admitted to the hospital.
Time of Update: 2021-12-27
In this study, the researchers found that when FABP4 is secreted from fat cells and enters the blood, it combines with adenosine kinase and nucleoside diphosphate kinase to form a Fabkin protein complex .
Research progress in the development of long-acting technologies for protein and peptide drugs (Part 1
Time of Update: 2021-09-05
To improve the stability of protein and peptide drugs, prolong the half-life in the body, and make it long-acting .
The first oral prescription for spinal muscular atrophy in China landed
Time of Update: 2021-08-26
The global multi-center clinical trial FIREFISH of a new drug "Lisporan" for the treatment of rare spinal muscular atrophy jointly participated by Fudan Pediatrics has made new breakthroughs in the world, and the results were published in the New England Journal of Medicine recently .
Metoclopramide, Domperidone, Cisapride... How to treat diabetic gastroparesis
Time of Update: 2021-08-08
Recommend low-fat, low-fiber, small particle or liquid diet, start with restricting intake of "difficult food" in the initial stage, and gradually tighten it (the basic principle is that solids need to be ground into particles ≤ 2 mm in diameter in order to be removed from the stomach as soon as possible Emptying, otherwise the lipids in the small intestine will stimulate the gastrointestinal feedback mechanism and cause delayed gastric emptying) .
Science: Scientists have isolated genes related to weight control
Time of Update: 2021-07-31
References : P ARSA Akbari , Ankit Gilani Sequencing of 640,000 exomes Identifies GPR75 variants Protection from Associated with Obesity Science 02 Jul-2021: Vol.
abf8683 References References : : P ARSA Akbari , Ankit Gilani Sequencing of 640,000 exomes Identifies GPR75 variants Protection from Associated with Obesity Science 02 Jul-2021: Vol.
New ideas, new drugs, new recommendations, writing experts will take you to "Consensus
Time of Update: 2021-06-22
First of all, Professor Ma pointed out that for patients with T2DM combined with CVD, the "Consensus" introduced to cardiologists a new type of hypoglycemic drugs that can effectively reduce blood sugar and improve prognosis, including glucagon-like drugs.
The relationship between the duration of type 2 diabetes and the risk of dementia
Time of Update: 2021-06-02
This article is from the NEJM Journal Watch (NEJM Journal Watch) Duration of Type 2 Diabetes and Risk for Dementia.
Commenting on these results clarified the role of duration of type 2 diabetes in the onset of dementia.
Large quantities of food of unknown origin seized and destroyed in Liangshan Province, Vietnam
Time of Update: 2021-05-07
html" class="zdbq" title="Food related food information" target="_blank">Food Partner Network News reported on the official website of the Vietnam General Administration of Market Supervision on April 6, 2021: The Market Supervision Bureau of Liangshan Province recently enforced the law to conduct a safety inspection on a suspicious vehicle and found many illegal foods.
Nat Commun: How will the once "hot" chloroquine affect the mortality rate of new crown patients
Time of Update: 2021-04-22
). Manage FDARecently, researchers conducted an investigation aimed at estimating the impact of hydroxychloroquine and chloroquine on the survival of new crown patients from all current published and unpublished randomized clinical trial (RCT) evidence.
Yesterday, today and tomorrow of the broiler breeding industry
Time of Update: 2021-04-18
R2C-，R2C-，Figure 5 Broiler breeding systemR2C-， In order to meet the market's demand for chicken quality and animal welfare, some European countries also have a small number of slow-speed and colored-feather broiler products that are similar to my country's yellow-feather broilers.