Application of Presens Sensor Plugs in Microfluidics
Time of Update: 2022-09-10
Gene expression analysis of TNFα, IL-6, and iNOS at the end of 24 hours showed significant fold changes, confirming M1 polarization of LPS-stimulated microglia under dynamic microfluidic culture .
What is the secret to scientific weight loss and noise reduction
Time of Update: 2022-08-25
. EMS-GRIVORY's proprietary EBM series blow-molded nylon pipes have been successfully applied to the intercooling cooling pipes of many OEMs. While fully meeting the performance requirements of the original metal or rubber pipes, they are designed with a more convenient structure (3D Blow molding technology) Lighter weight increases production efficiency and saves a lot of money .
Nature sub-journal: New breakthroughs in AIDS research, CRISPR screening finds multiple new therapeutic targets
Time of Update: 2022-04-27
The study used CRISPR screening technology to identify and characterize genes in human blood that are important for HIV infection, and found 86 genes that may play an important role, more than half of which had not previously been found to play a role in HIV replication .
Antibody diversity decreases with age
Time of Update: 2022-04-23
A team of researchers led by Dario Ricardo Valenzano investigated whether the immune system of short-lived killifish ages .
"If different antibodies decrease with age, this could lead to a decrease in the ability to respond to infection .
Time of Update: 2022-02-18
In a new study published in Cell in the early morning of January 20, Beijing time , a research team from the University of Basel in Switzerland found that T cells can effectively eliminate abnormal or infected cells only in a magnesium-rich environment.
PLOS Genetics: Choline transporters in the brain are necessary to call up unwanted information
Time of Update: 2021-12-25
In addition, previous studies have shown that changes in choline transporters are related to attention deficit hyperactivity disorder (ADHD) .
The findings of this study open up a new way for future research on the role of choline transporters in diseases related to habituation .
Alz Res Therapy: Hypometabolic anterior cingulate gyrus can predict frontotemporal dementia
Time of Update: 2021-12-03
explored whether P301L MAPT mutation carriers have asymptomatic neuronal dysfunction measured by FDG-PET, and whether the pattern of low metabolism is different from the pattern of atrophy .
Diabetologia: The correlation between birth weight and diabetes penetrance in HNF4A-MODY patients
Time of Update: 2021-12-02
In this study, we sought to determine the relationship between the birth weight of individuals with HNF4A mutations and the penetrance of diabetes, which can provide insights into the relationship between fetal and adult insulin secretion capacity .
The Zhejiang University team has developed a new polymer micelle, which is expected to treat intervertebral disc degeneration
Time of Update: 2021-11-04
These two molecules can protect human ADSCs from oxidative stress and promote cell differentiation into a nucleus pulposus-like phenotype, thereby treating intervertebral discs.
X-ray analysis to assess the height of the intervertebral discConcluding remarksIn summary, researchers have developed an injectable esterase-responsive micelle PAKM that delivers APO and KGN to the intervertebral disc .
Pressing on the "throat" of solid tumors, the results of preclinical experiments are surprising
Time of Update: 2021-09-13
This discovery, published in the journal Science Advances, will help researchers develop new treatment strategies to limit the development of solid cancer tumors .
Dedhar said: "We now know that CAIX enzymes can prevent cancer cells from dying from iron death .
Cell: Engineered CAR T cells release endogenous RNA to awaken solid tumors to respond to treatment
Time of Update: 2021-09-12
In addition to helping recruit the body's natural immune system, studies have shown that RN7SL1 can also improve the function of CAR-T cells themselves .
Scientists propose new ideas for diagnosis and treatment of "pan-vascular disease
Time of Update: 2021-08-01
Weng Jianping’s team and collaborators recently put forward a new theory that “the imbalance of vascular endothelial cell homeostasis is a key mechanism for the progression of pan-vascular disease.
The bigger the pupil, the higher the intelligence: the relationship between the eyes and the brain is more complicated than you think
Time of Update: 2021-06-22
We found that a larger baseline pupil size is related to higher fluid intelligence and attention control ability (and also slightly related to working memory ability), which indicates that there is a wonderful relationship between the brain and the eyes .
Sanofi's Pompe disease treatment has received FDA priority review and is expected to become a new standard treatment
Time of Update: 2021-02-24
a key double-blind drug-controlled Phase 3 clinical trial to assess the safety and efficacy of avalglucosidase alfa compared to α-glucosidease (standard treatment) in patients with late-hair pompeidase.
Nature: Scientists reveal new molecular mechanisms that regulate the anti-tumor activity of immune cells
Time of Update: 2021-02-14
Subir Biswas, a researcher, said the results of this study show that the use of immunotherapy may enhance the coordinated response of the body's B-cell nuclear T-cells against ovarian cancer, which is also a immunogenic disease that is resistant to checkpoint inhibitors, which often show better disease treatment.