Nat Neurosci: Science has found that electrical stimulation through the scalp can improve a person's memory
Time of Update: 2022-09-30
Based on the study, the team showed that stimulating the dorsolateral prefrontal cortex (a region near the front of the brain) with high-frequency currents improves long-term memory, while stimulating the sub-parietal lobe located deeper in the brain, enhancing working memory with low-frequency currents.
Is there no cure for advanced cancer
Time of Update: 2022-09-06
Similar to Ms. Wu's situation, more than 30 patients have joined the TIL clinical trial in the Obstetrics and Gynecology Department of Shanghai Tenth Hospital with the idea of "last choice", of which 16 patients have completed all treatment and can be evaluated for efficacy, 16 Like her, 10 were under control, and 60% of the responses were encouraging .
Two articles jointly explain the reasons for X's silence
Time of Update: 2022-08-12
Kalantry's lab, working closely with Shigeki Iwase's lab, also at the University of Michigan, found that since an X-linked gene, Kdm5c, is more expressed in females than in males, it induces Xist in females, thereby selectively making X- inactivated .
Metformin turned into a "God Assist" in the treatment of Alzheimer's disease
Time of Update: 2022-05-27
Based on this, the research team of Yang Lichao used the interaction between host and guest molecules to prepare an Aβ-responsive dual-drug inclusion complex (MPD), which not only has superior biological stability and targeted release, but also It has synergistic anti-dementia effect by increasing the clearance rate of Aβ and inhibiting the activity of AchE .
Insecticides labeled with fluorescein
Time of Update: 2022-04-28
At the heart of the technology is a new method of enzymatically synthesizing analogs of luciferin, the substance that makes fireflies glow .
The researchers, led by Pimchai Chaiyen, began a new enzymatic cascade for the synthesis of luciferin analogs from phenolic compounds, which they called the HELP reaction .
Neurons from stem cells can predict psychosis and cognitive deficits in schizophrenia, new study finds
Time of Update: 2022-01-25
That said, no other study has shown a strong link between neural models derived from a patient's stem cells and clinically relevant features of the same person's psychiatric disorder .
The ability to resist new coronavirus infection prompts a new vaccine target "Nature" paper
Time of Update: 2021-12-08
A study published by "Nature" Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 pointed out that past exposure to other coronaviruses may increase the body's speed of clearing the new coronavirus (SARS-CoV-2) , Because the immune system can remember viral replication proteins that are highly conserved among different coronaviruses .
Screening and monitoring of liver cancer, 19 guidelines recommendations are here
Time of Update: 2021-12-05
Cirrhosis of the liver and chronic hepatitis B without antiviral treatment are the main causes of liver cancer in China .
The recently released "Guidelines for Stratified Screening and Surveillance of Primary Liver Cancer (2020 Edition)" provide guidance for scientifically identifying high-risk groups of liver cancer and stratified monitoring .
Diabetologia: The role of circulating Galectin-1 in type 2 diabetes and chronic kidney disease
Time of Update: 2021-12-02
Using the large population-based Malmö Diet and Cancer Study- Cardiovascular Cohort Study (MDCS-CC), our goal is to check whether circulating Galectin-1 levels are associated with the onset of CKD and type 2 diabetes, independent of the established Risk factors .
Cardiovasc Diabetol: 3-year prognosis of patients with diabetes (pre-stage) after percutaneous coronary intervention with drug-eluting stents
Time of Update: 2021-12-02
The incidence of all primary endpoints in diabetic patients is higherMajor bleeding rate of three groups of subjectsMajor bleeding rate of three groups of subjectsCompared with individuals with normal blood sugar, the rate of major bleeding in prediabetes and diabetic patients was also significantly higher (3.
Decoding Rheumatism Live Room ⑤ Rheumatism can also cause acute and critical illness
Time of Update: 2021-11-16
Because IPAF can significantly reduce the survival rate of patients, and seriously affect the recovery of the disease, if the treatment is not early and standardized, it will cause irreversible damage, and eventually respiratory failure and pulmonary fibrosis will lead to death.
An article to understand the application progress of ADCs, bispecific antibodies and trispecific antibodies targeting BCMA in MM
Time of Update: 2021-11-04
. Table: Bispecific antibodies in clinical development of multiple myeloma Finally, trispecific antibodies are in the pre-clinical development stage, with dual MM surface marker targeting effects, trying to increase the specificity of MM cells .
P53 upstream & synthetic lethal: the target "ATM" track has great potential
Time of Update: 2021-11-03
? XRD-0394 development company is X Rad Therapeutics, which is administered orally and is a dual ATM/DNA-PK inhibitor for the treatment of metastatic, locally advanced or recurrent solid tumors .
Express Roche's PD-1/LAG-3 bispecific antibody applied for clinical application in China
Time of Update: 2021-08-09
Source: Guanlan PharmaceuticalThe Center for Drug Evaluation (CDE) of the China National Medical Products Administration showed that the RO7247669 injection being developed by Roche has been declared for clinical use in China and was accepted on July 2 .
A new method to quickly repair peripheral nerve injury
Time of Update: 2021-07-27
The researchers measured the direction of cell growth and found that with the help of a gel that combines collagen and NGF coated particles, they can guide and promote cell growth .