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ESMO 2022 Professor Dongliang Yu: Incidence of EGFR mutation and disease prognosis in patients with locally resectable NSCLC in the real world
Time of Update: 2023-01-05
2Study designThe main inclusion criteria for the EXERPOS-GFPC study were: patients with local NSCLC who underwent continuous surgery in France from January 2018 to December 2019, and the study collected data including demographic and clinical data, type of surgery, stage, disease recurrence, and treatment in case of disease recurrence.
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Effector proteins that help fungi invade multiple host plants
Time of Update: 2023-01-01
Recently, a research group of professors at the University of Córdoba in Spain published an online report entitled Conserved secreted effectors contribute to endophytic growth and multihost plant compatibility in a at The Plant Cell The Vascular Wilt Fungus paper reveals that Fusarium oxysporum, the blight-inducing fungus, secretes a group of effector proteins that enable it to colonize the roots of a variety of plants.
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Nat Genet Zhang Zhao's group reveals the new role of reversal colons in activating the innate immune system to resist the invasion of foreign viruses for a long time
Time of Update: 2023-01-01
Reverse locons are present in almost all eukaryotes and are extremely abundant in the genome. In humans, reversers make up up to 38% of the genome. After the activation of the reverse locon, the mRNA,
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Neuron's new view on the blood tumor barrier
Time of Update: 2022-11-04
Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity Huang's team, co-led by Chen Xin, Ali Momin and Siyi Wanggou of SickKids, found that medulloblastoma tumor cells rely on ion channels "pressure sensitive," a protein that plays an important role in cell signaling, to help form a blood-tumor-related barrier.
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Cells: Research status and challenges of TCR-T cell therapy
Time of Update: 2022-10-31
These challenges include: (1) immunotoxicity caused by targeting normal tissue; (2) insufficient or transient expression of TCR in engineered T cells; (3) T cell depletion and dysfunction; (4) tumor immune evasion, and (5) most cancer patients lack effective tumor-specific antigens as targets.
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Suspension of REM sleep neonucleus and loop mechanism
Time of Update: 2022-10-31
On October 25, 2022, Professor Huang Zhili's team from the Department of Pharmacology published a paper in the journal Cell Discovery, reporting the mechanism of terminating the new nucleus of REM sleep and neural circuits, and found that GABAergic neurons located in the dorsal part of the midbrain nucleus (dDpMe) in the deep brain stem can efficiently terminate REM sleep, prevent REM sleep from being too long, and reduce the occurrence of narcolepsy cataplexy.
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The OX40 protein has the potential to alleviate the main complications of leukemia treatment
Time of Update: 2022-09-30
Researchers at Baylor College of Medicine and its partner institutions have engineered immune cells to control two major life-threatening complications, graft-versus-host disease (GvHD) and cancer recurrence, which usually occur after allogeneic hematopoietic stem cell transplantation for leukemia (allo-HSCT).
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Reward will meet you at the 7th Trade and Trade Bio-Industry Conference in 2022
Time of Update: 2022-08-30
From August 25th to 27th, the "2022EBC 7th Trade and Trade Bio-Industry Conference" will be held in Suzhou International Expo Center . As the largest and most influential bio-industry conference in Ch
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Zhongke New Life: Clinical Longitudinal Cohort Fixed RNA Single-Cell Transcriptome Promotion
Time of Update: 2022-08-30
If you are interested in clinical cohort single-cell sequencing research, you can scan the QR code below to add "Zhongke New Life" enterprise WeChat assistant consultation Zhongke New Life Clinical Longitudinal Cohort Fixed RNA Single Cell Transcriptome Fresh Taste What is the hottest omics technology right now?
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Ji Guangju's group reveals the important role and mechanism of CUGBP1 in mouse myocardial regeneration
Time of Update: 2022-03-08
On February 8, 2022, Ji Guangju's research group from the Institute of Biophysics, Chinese Academy of Sciences published the research results online entitled "CUGBP1, a crucial factor for heart regeneration in mice" in " Cell Death & Disease " .
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Cell: SARS-CoV-2 variants similar to Delta variants can exacerbate the new crown pandemic
Time of Update: 2022-01-01
In a new study, researchers from the Chen Zengxi School of Public Health of Harvard University in the United States constructed a mathematical model and found that a SARS-CoV-2 variant with similar characteristics to the Delta variant---enhanced transmission and The ability to infect previously infected/vaccinated people --- will cause a more serious pandemic, resulting in more infections and breakthroughs than the SARS-CoV-2 variant that has one of these two characteristics alone Sexual infection/reinfection .
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Cancer Cell: Many patients with double vaccinations have poor immune response
Time of Update: 2021-11-02
The author believes that in the absence of the protection usually provided by vaccines, this study shows the importance of continuing to take public health measures to limit the spread of SARS-CoV-2, and the urgency of strengthening the plan, especially in the United Kingdom delta type When the virus spreads highlyPatients with solid cancers, such as breast cancer, urology, or skin cancer, also respond poorly to a single dose of the vaccine, with a seroconversion rate of only 38% .
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Nature Cell Biology: A new method for RNA-binding protein target research LACE-seq
Time of Update: 2021-08-10
In the early morning of June 10, 2021, Xue Yuanchao's research group from the Institute of Biophysics, Chinese Academy of Sciences and his collaborators published an online publication entitled "Global profiling of RNA-binding protein target sites by LACE-seq" in the journal Nature Cell Biology .
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Vietnam Vinh Hoan invests in Singapore Cell Meat Project
Time of Update: 2021-08-04
The funds will be used for the cell meat production facility invested by Shiok in Singapore .
The funds will be used for the cell meat production facility invested by Shiok in Singapore .
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CELL DEATH DIFFER phosphorylation-dependent ubiquitin degradation substrate research has made progress
Time of Update: 2021-08-03
On July 2, 2021, the team of Minjia Tan of Shanghai Institute of Materia Medica, Chinese Academy of Sciences and the team of Professor Bin Liu of Jiangsu Ocean University jointly published an online publication entitled "Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an" in Cell Death & Differentiation .
