Nature sub-journal: New breakthroughs in AIDS research, CRISPR screening finds multiple new therapeutic targets
Time of Update: 2022-04-27
The study used CRISPR screening technology to identify and characterize genes in human blood that are important for HIV infection, and found 86 genes that may play an important role, more than half of which had not previously been found to play a role in HIV replication .
Express delivery only needs to be taken once a month, and the Phase 2 clinical results of long-acting HIV preventive therapy are positive
Time of Update: 2021-08-05
After 24 weeks, monthly oral islatravir showed good safety and tolerability, and 8 weeks after receiving the last dose of treatment, the level of islatravir in the subjects’ peripheral blood mononuclear cells (PBMCs) remained high To maintain the pharmacokinetic threshold of drug efficacy .
Eur Heart J: HIV infection is associated with thoracic-abdominal aortic aneurysm
Time of Update: 2021-07-29
Heart blood vessels The researchers recruited PLWH patients over the age of 40 (n=594) from the Copenhagen HIV infection comorbidity study, and matched the age and sex with uninfected controls (n=1188) from the Copenhagen general population study .
Cell Rep: Screening new technologies based on phase change interaction and revealing the composition of the new coronavirus high-order protein complex
Time of Update: 2021-07-27
How to efficiently replicate the virus developed by Li Pilong's group? How is the replication complex formed? How does the host's immune response escape? A series of viral life history events like thi
NEJM: ALVAC-HIV vaccination program failed in South Africa Phase 2b-3 clinical study
Time of Update: 2021-03-26
Prevention During the 24-month follow-up, 138 participants in the vaccine group and 133 participants in the placebo group were diagnosed with HIV-1 infection (hazard ratio 1.
During the 24-month follow-up, 138 participants in the vaccine group and 133 participants in the placebo group were diagnosed with HIV-1 infection (hazard ratio 1.
AIDS treatment revolution: FDA approves first long-acting HIV drug that requires only one treatment per month
Time of Update: 2021-01-31
On January 21st, Cabenuva, developed by Janssen Pharmaceuticals, a subsidiary of global pharmaceutical giant Johnson and Johnson, in partnership with ViiV Healthcare, a well-known AIDS treatment company, was approved by the U.S. Food and Drug Administration (FDA) to replace traditional antiretroviral programs for treating adult patients infected with human immunodeficiency virus type 1 (HIV-1).
Time of Update: 2020-12-04
The firstin situ hybridization experiments were described by two groups of researchers in 1969, John et al.
and Gall and Pardue (reviewed in ref.
Radioactively labeled RNA probes were used to localize specificDNA sequences within the nuclei ofXenopus laevis ( 2 ).
Advances in the study of partial genetic research of influenza viruses
Time of Update: 2020-08-11
A team of researchers at the University of Tokyo and Kyoto University in Japan recently published research in the British journal Science that influenza viruses acquire insufficient genes from infected cells and multiply when some of their genes are insufficient, Japanese media reported.
Nature Heavyweight: Bypass immune checkpoint IL-18BP restrictions, IL-18 immunotherapy progress again
Time of Update: 2020-07-18
Image Source: the results of nature mouse colon cancer and melanoma models showed that the tumor inhibitory effect of dr-18 was better than that of IL-18 and PD-1 antibodies.
Chinese research shows that maternal obesity increases the risk of liver cancer in future generations
Time of Update: 2020-07-18
in this new study, the researchers found a microRNA in the mothers of obese mice, which seemed to be susceptible to liver cancer, thus increasing the possibility of liver cancer development in their offspring and offspring.
Global Fund supports 10 AIDS prevention and control demonstration zones in Hubei
Time of Update: 2020-07-07
reporters from November 13-14 in Wuhan, Hubei Province, the annual meeting of the Global Fund AIDS Project was informed that the third round of China Global Fund AIDS project supported the province'
FDA approves a high-precision approach to HIV detection
Time of Update: 2020-07-02
Recently, a more accurate HIV test in the United States approved by the FDA (Food Drug Administration), which means that the early diagnosis of AIDS will be further advanced, for patients to win m
The first thymus tissue map successfully drew the human body "Google map" and further
Time of Update: 2020-02-24
The thymus is the organ responsible for the maturation of many types of T cells, which are the immune system that protects us from infection Thymus is the largest and most active thymus in childhood I
Clinical research progress of China's Class 1 new drugs in 2017
Time of Update: 2017-11-23
Source: Sina Pharma 2017-11-23 since March 4, 2016, after CFDA issued the work plan on the reform of chemical drug registration and classification, China's class 1 is redefined as an innovative drug t