PNAS: Effects of fentanyl on the brain
Time of Update: 2022-09-07
key takeawayElectroencephalogram (EEG) tests showed fentanyl's effects on the brain and showed that the drug stops breathing before people experience other noticeable changes and lose consciousness .
Oral version of drug protects against SARS-CoV-2 in mice
Time of Update: 2022-08-11
SummaryDespite the rapid introduction of a safe and effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the COVID-19 pandemic remains uncontrollable, underscoring the need for the development of highly effective antiviral drugs .
The cornerstone of nano-drug delivery-the role of EPR effect in human tumors
Time of Update: 2022-06-26
In view of this, researchers such as Wenguang Liu of Tianjin University have developed an in vitro perfusion model to study the role of EPR in human kidney tumors in real time through X-ray computed tomography (CT) .
Online procurement of 3 drugs involves original research, reference preparations and innovative drugs
Time of Update: 2022-05-27
On March 8, 2022, the Shanghai Sunshine Purchasing Network released the first batch of original research/reference preparations/innovative drugs online purchase announcement in 2022 .
16Release date: 2022-03-08Pharmaceutical manufacturers:According to the "Notice on the Full Implementation of the Public Negotiated Procurement of Drugs on the Internet" (Huyaoshi  No.
Spring blossoms in March, and a large number of pharmaceutical companies announce the approval of drugs
Time of Update: 2022-05-01
On March 2, Fosun Pharma’s subsidiary Fosun Kite announced that it had received approval from the State Drug Administration for the approval of its CD19-targeted autologous CAR-T cell therapy product FKC889.
EHJCP: Cardiorenal risk comparison of celecoxib versus naproxen or ibuprofen for arthritis
Time of Update: 2022-04-18
24,081 patients requiring NSAIDs for osteoarthritis or rheumatoid arthritis and at increased cardiovascular risk were randomized to receive celecoxib, ibuprofen, or naproxen .
The current prespecified secondary analysis assessed the incidence of prespecified composite cardiorenal outcomes [adjudicated renal events, hospitalization for congestive heart failure (CHF), or hospitalization for hypertension (HTN)] in the intent-to-treat (ITT) population.
Lethal mutagenesis: a feasible antiviral strategy with unknown risks
Time of Update: 2022-03-08
Click on the blue text above to follow us Ronald Swanstrom and Raymond Schinazi propose in a Perspective that antiviral strategies that allow RNA viruses to produce genetic mutations so fast that the virus cannot remove those harmful mutations are used in With the recently approved COVID-19 treatment molnupiravir, this strategy may work, but it could also pose unknown risks to the host .
Better Pharmaceuticals is working hard
Time of Update: 2021-12-26
At present, more than 30 domestic companies have submitted applications for the listing of ticagrelor tablets under the new registration classification, of which 20 have been approved for production and deemed to have been reviewed.
Cell therapy technology is changing rapidly, does CAR-T still have advantages
Time of Update: 2021-12-06
In August of this year, Novartis announced that the CD19 CAR-T therapy Kymriah second-line treatment of aggressive B-cell non-Hodgkin lymphoma (B-NHL) Phase 3 clinical BELINDA did not meet the primary endpoint EFS .
Food Supervision and Sampling Inspection Quality Notice of Foshan Market Supervision Administration (No. 23, 2021
Time of Update: 2021-12-03
Heavy metal pollution (1) The three-spot crabs, flower crabs, and cadmium (calculated as Cd) sold at the Ruilulang seafood stall in Gaoming District, Foshan City, do not meet the requirements of the national food safety standards .
Can you still get gout after a light diet
Time of Update: 2021-11-15
Perhaps some patients may wonder: they don’t look fat, their body mass index is normal, why is blood uric acid still high, or even gout?
Current research has found that some genetic defects will affect purine metabolism and uric acid excretion, and eventually lead to hyperuricemia and gout .
Clin Trans Gastroenterology: High adalimumab drug levels after induction therapy can predict disease biological remission at week 24 in patients with Crohn's disease
Time of Update: 2021-10-20
This study explored whether the adalimumab drug level (ADL) at the early 4th week can predict biological remission at the 24th week .
Post-Induction High Adalimumab Drug Levels Predict Biological Remission at Week 24 in Patients With Crohn's Disease.
Nature Sub-Journal: Genes that control the severity of colon cancer
Time of Update: 2021-09-20
Picture: Majid Kazemian and a group of scientists discovered that the TCF-1 gene plays a key role in controlling TReg cells and affects the severity of colon cancer .
What to pay attention to when taking enzalutamide
Time of Update: 2021-09-05
It is mainly used for men with symptoms of prostate disease.
Many men can prevent the occurrence of prostate cancer symptoms after taking it, and it can also inhibit the growth and spread of cancer cells in the body.
It is expected to achieve functional cure for hepatitis B and complete the first administration of RNA destabilizer
Time of Update: 2021-08-27
EDP-721 is a new oral RNA destabilizing agent (destabilizer), as part of the all-oral combination therapy being developed for the treatment of chronic hepatitis B virus (HBV) infection, hepatitis B aims to achieve functional cure .