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Clinical overview of next-generation CAR-T cell therapy
Time of Update: 2023-01-05
Advances in immunology and molecular engineering have led to the construction of a new generation of CAR-T cells armed with a variety of molecular mechanisms, including additional co-stimulatory domains, safety switches, immune checkpoint regulation, cytokine expression, or knockout of therapeutic interfering molecules.
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The molecular and cellular mechanism by which the kinesin nKCBP is revealed by microorganisms regulates symbiosis in rhizobia
Time of Update: 2022-11-15
Article link: style="display: none;">On November 1, 2022, the Kong Zhaosheng Research Group of the Institute of Microbiology of the Chinese Academy of Sciences published a research paper in Nature Plants (A Legume Kinesin Controls Vacuole Morphogenesis for Rhizobia Endosymbiosis), revealing the molecular and cellular mechanism by which the kinesin nKCBP regulates symbiosis in rhizobia.
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The special corrosion inhibitor for oil and gas ultra-deep wells was successfully developed
Time of Update: 2022-09-20
Recently, China National Petroleum Corporation Engineering Materials Research Institute Co. , Ltd. developed a special ultra-high temperature acidification corrosion inhibitor for 2205 duplex stainle
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Zhongyuan Petrochemical develops new polypropylene products
Time of Update: 2022-09-16
The appearance is beautiful, the benefit is good, and the market prospect is broad On December 27, Zhongyuan Petrochemical successfully developed and produced 95 tons of high melt strength polypropylene new product PPH-E03, which has high puncture resistance, good shrinkage and certain shrinkage stress, and is used to make shrinkable films.
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Acanthoxylin B
Time of Update: 2022-04-08
Thin layer plate silica gel GDeveloping solvent chloroform - methanol - water (1) to prepareCheck 2% vanillin sulfuric acid solution, heated at 105°C until the spots appear clear, check under sunlightHigh performance liquid chromatographyChromatographic column Agilent SB C 18 , 5um (4.
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my country's refining capacity over 100 million tons of petrochemical industry is expected to maintain a 4%-5% growth rate during the 13th Five-Year Plan
Time of Update: 2022-02-19
At the 3rd China Petroleum and Chemical Sustainable Development Forum held in Shanghai a few days ago, experts believe that China’s demand for refined oil has slowed down sharply, but there is still a large shortage of basic organic chemical raw materials such as aromatics and olefins.
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Method for determination of avermectin drug residues (2
Time of Update: 2021-10-22
reported the use of acetonitrile extraction, TFAA post-column derivatization, AVM as an internal standard, and the determination of IVM and DOR in pig liver by HPLC-FLD .
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My scientist reveals the molecular mechanism of ketamine's rapid antidepressant
Time of Update: 2021-07-30
This study clearly reveals the molecular mechanism of the rapid antidepressant effect of ketamine, and provides an important theoretical basis for the design of new antidepressant drugs, especially to promote the development of ketamine-derived drugs, and brings new dawn to patients with depression .
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The structure and workings of DNA replicators have been revealed for the first time
Time of Update: 2021-03-14
It has been known that during DNA replication, double-stranded DNA is disintegred into leading and hysteresic chains, respectively, as replication templates, while lead chains and lag chains together form a structure called a "copy fork." researchers found that dna polymerases, helixases, and trigger enzymes bind tightly around "T-shaped" replication forks in a replica structure, forming a multi-layered, tight molecular structure.
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Progress has been made in the study of deep-sea energy ecosystems
Time of Update: 2020-12-31
Flat-end deep-sea top clams are one of the most representative invertebrates in the cold spring area of the South China Sea, and have a symbiotic relationship with methane oxidizing bacteria.
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Refinement of Protein and Nucleic Acid Structures
Time of Update: 2020-12-29
Refinement constitutes the last of the three main steps in the crystallographic establishment of a molecular structure, which are fast, crystal growth and data collection; second, phase determination and calculation of electron density maps; and third, model building and refinement.
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Sample Preparation for SFM Imaging of DNA, Proteins, and DNAProtein Complexes
Time of Update: 2020-12-03
Recently available instruments that combine fluorescence with topographic imaging allow the identification of specific molecular components in complex assemblies, which broadens the applications and increases the information obtained from direct imaging of molecular complexes.
We also describe special considerations for combined fluorescence and topographic imaging of molecular complexes.
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Aminimides as Peptidomimetics
Time of Update: 2020-11-30
The mimicry of these natural interactions has been an important and useful strategy for the development of metabolically stable drugs capable of being administered orally (1 –4 ).
The aminimide bond has two resonance forms as shown in Fig. 1 .
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Effect of organic additives on the interface stability of polymer coatings
Time of Update: 2020-11-05
A new study describes the effects of additives on the interface stability of polymer coatings in fluoric acid-based Ti and Zr treatments.
However, in the long run, organic additives have been shown to be harmful to the adhesion of polyester coil coatings.
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Don't worry! Formal plastic-packed foods do not cause cancer
Time of Update: 2020-09-30
Rumor has it that when food is placed in high temperatures, chemicals produced by plastics can cause 52 types of cancer.
therefore, the market formal manufacturers use of food plastic packaging is in line with national standards, food safety is guaranteed, there is no possibility of eating plastic packaging of food carcinogenic.
