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Hippo signaling does not direct normal organ growth
Time of Update: 2023-01-06
According to a new study, the Hippo signaling pathway — a genetic program thought to play a central role in organ development — does not direct normal organ growth in fruit flies and mice.
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Hippo signaling does not direct normal organ growth
Time of Update: 2023-01-06
According to a new study, the Hippo signaling pathway — a genetic program thought to play a central role in organ development — does not direct normal organ growth in fruit flies and mice.
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For the first time in primates, it has been shown that maternal unhealthy diet and obesity can affect the fetus's immune system
Time of Update: 2022-11-15
Oleg Vallamov of the National Primate Research Center in Oregon said: "This finding is the first to prove in primates that maternal unhealthy diet and obesity can damage the immune system of the developing fetus.
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How does Parkinson's spread in the brain
Time of Update: 2022-10-02
"Our findings also suggest that lysosomal exocytosis may be a general mechanism for processing neuronal aggregation and anti-degrading proteins in normal, healthy environments and neurodegenerative diseases," said the study's senior author, Dr. Manu Sharma, who is an assistant professor of neuroscience at the Fellowes Family Institute of Brain and Mind at the Weill Cornell School of Medicine and the Alzheimer's Institute of Diseases in Appell.
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Structural basis for autoinhibition of the human NHE3-CHP1 complex
Time of Update: 2022-08-11
IntroductionNot applicable+/H+Exchange or anti-transporters (NHEs/NHAs) are integral membrane secondary active transporters present in all organisms examined to date, a notion that supports their origin in an early stage of biosphere evolution (1).
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In reducing blood lipids and improving fatty liver, which one of these two local black teas is better
Time of Update: 2022-04-24
Unlike the effect of alleviating fatty liver, KBT or DBT treatment had no significant difference in the changes of mRNA expression of hepatic lipid metabolism genes .
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A special subset of immune cells can reduce kidney damage
Time of Update: 2021-09-18
For example, special cells called mononuclear phagocytes (MNPs) play an important role in absorbing and processing damaged cells, removing invasive pathogens and other foreign bodies, and regulating immune responses .
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Cell Sub-Journal: This molecule makes the adult hippocampus nerve regeneration firstly strong and then weak, and finally "lying down
Time of Update: 2021-06-30
This indicates that during the transition from adolescence to adulthood, the differentiation of neural stem cells proliferating in the hippocampus gradually decreases, gaining the ability to restore rest and maintaining the stability of the number of neural stem cells .
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Nat Commun: Functional characteristics of early immune cells
Time of Update: 2021-01-22
the characteristics of early dedring cells differ from those of mature mice, they still have the ability to trigger an effective immune response.
S. Schraml said: "Our data suggest that by adapting the properties of immunoantigens to the specific abilities of early-childhood degeneration cells, it may improve the effectiveness of vaccination in children.
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Skin cells help mice see the light again
Time of Update: 2020-12-30
the new study, the researchers said it was possible to skip stem cell steps and reprogram skin cells directly into the retina.
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Blood: Iron chelation for the treatment of hemolytic anemia and skin photosensitivity for congenital erythropoietin
Time of Update: 2020-07-30
treating uroS defects with oxytotone and peripheral blood CD34 plus red blood cells from patients with CEP inhibited the expression of the ferrite-dependent proteins ALAS2 and IRP2 and reduced the production of radon.
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Nat Microbiol. The Zhu Kui/Shen Jianzhong team discovered a new broad-spectrum antibacterial additive
Time of Update: 2020-07-28
in this study, a novel linear short chain broad-spectrum antibacterial synergist slap-s25 was reported for the first time, which can improve the antibacterial effect of several commonly used clinical antibiotics such as tetracycline, vancomycin, ofloxacin, rifampicin and polymyxin against multidrug-resistant Escherichia coli and other gram-negative bacteria.
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The Zhongbo team at Wuhan University found an important function and mechanism for ubiquitinase to regulate the immune and tumor occurrence of intestinal infections
Time of Update: 2020-07-18
the expression level of USP25 in colon tissue or colon epithelial cells induced by bacterial infection and DSS was significantly increased, which indicated that intestinal infection inhibited host anti infection immune response by up regulating the expression of USP25.
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PET imaging helps determine whether PD-1 tumor immunotherapy is effective
Time of Update: 2020-06-08
PD-1 is a protein on T cells and an important immunosuppressive molecule A growing number of anticancer drugs are designed to suppress PD-1, induce patients' T-cells to attack and kill cancer cells PD
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Nature: maternal protective antibody protects newborn from intestinal infection
Time of Update: 2020-01-26
January 23, 2020 / Biovalley BIOON / - -- breast milk has long been considered beneficial to newborns and protects them from certain infections In a new study, researchers from Harvard Medical School
