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Academician comments The study of "Cell" of the Chinese Academy of Sciences revealed the mechanism of action of morphine and fentanyl, and the powerful analgesic got rid of addiction is one step
Time of Update: 2023-01-06
The cooperation of Xu Huaqiang/Zhuang Youwen, Xie Xin's team and Wang Mingwei's team from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences revealed for the first time the mechanism of action of powerful analgesics fentanyl and morphine to recognize and activate μ opioid receptors (μOR), and systematically explored and deepened the understanding and understanding of the mechanism of μOR signaling regulation.
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Academician comments The study of "Cell" of the Chinese Academy of Sciences revealed the mechanism of action of morphine and fentanyl, and the powerful analgesic got rid of addiction is one step
Time of Update: 2023-01-06
The cooperation of Xu Huaqiang/Zhuang Youwen, Xie Xin's team and Wang Mingwei's team from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences revealed for the first time the mechanism of action of powerful analgesics fentanyl and morphine to recognize and activate μ opioid receptors (μOR), and systematically explored and deepened the understanding and understanding of the mechanism of μOR signaling regulation.
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Primate-specific genes are involved in the cell cycle processes of the brain in cancer and embryonic stages
Time of Update: 2022-12-30
The Daniel Zhang research group and collaborators of the Institute of Zoology, Chinese Academy of Sciences explored the above questions by integrating data from The Cancer Genome Atlas (TCGA), brain development transcriptome [10] and primate-specific gene collection [11], and the relevant results were published in Genome Biology (GB) on December 6, 2022, with the paper "Pan-cancer surveys indicate cell.
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Fudan University Science published an article to break the traditional cognition: the mystery of human oocyte spindle assembly
Time of Update: 2022-11-25
The correct assembly of the spindle is a key event for the smooth progress of mammalian mitomy classification and meiosis, and only the precise assembly of the spindle can ensure the correct separati
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Chinese scholars and overseas collaborators have made progress in the study of the mechanism of intestinal microflora disorders driving Crohn's disease
Time of Update: 2022-09-14
Figure Two mechanisms by which noD2 pathway inactivation drives crohn's disease (CD) occurrence. Above: Mutations in the NOD2 gene impair its ability to recognize ligands, and inactivation of the NOD
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Professor Song Yuqin welcomes the hope of cure for 200 patients with Benoda®, and jointly hopes for the 2-year OS survival rate
Time of Update: 2022-05-28
Professor Song Yuqin's Ruiki Orenza injection is currently marketed in China for r/r LBCL in adult patients after second-line or above systemic therapy, including DLBCL, high-grade B-cell lymphoma (HGBL) and follicular lymphoma (FL) Converted DLBCL et al .
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Do human stem cells contain cancer-causing mutations
Time of Update: 2022-04-25
The research team's breakthrough will help ease the recent controversy over the genetic stability of human embryonic stem cells .
Recent studies have shown that human pluripotent stem cells have been shown to increase the frequency of severe cancer-causing mutations .
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The latest discovery of Chinese scientists: the first non-coding RNA found to interact with myocardin
Time of Update: 2022-01-22
"When the scientists restored healthy CARMN levels in a common model of vascular disease, unhealthy cell proliferation and scarring within blood vessels was significantly reduced, and when they removed CARMN from smooth muscle cells, the damage response was exaggerated, leaving little room for blood flow small .
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Nature: How do active DNA molecules with therapeutic potential work
Time of Update: 2022-01-07
Its purpose is to target unwanted RNA molecules in viruses, cancers or damaged nerve cells, using DNAzymes to attack and destroy them .
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These 25 batches of unqualified food in Chongqing are on the black list, involving brewing soy sauce, sorghum liquor, black sesame, etc
Time of Update: 2021-12-02
is sold at Ran Haodong Convenience Store in Youyang County The pure mung bean paste cake produced does not meet the national food safety standards in terms of acid value (calculated as fat); the sorghum liquor produced by Hu Quanfan, No.
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Four challenges and countermeasures for CAR-T treatment of solid tumors
Time of Update: 2021-11-14
Reduce immunosuppression in TME (Source: American Journal of Cancer Research) At the same time, since TGFβ is an important immunosuppressive pathway, blocking TGFβ signaling can also improve the anti-tumor effect of CAR-T .
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Some parts of your body are too sensitive
Time of Update: 2021-10-21
▲When the glabrous area (adult) is touched, the neuron signals in a specific brain area will be stronger, which is in sharp contrast with the hairy area (picture source: reference [2]) but the brain The stem is also eccentric, and brainstem neurons will have a stronger connection with sensory neurons in the hairless area, amplifying the signs of sensitive skin .
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DNA supercoiling: DNA structure itself is involved in genome regulation
Time of Update: 2021-09-11
DNA supercoiling is an important factor that controls gene expression, not just collateral damage that cells must resolve . The two-meter-long DNA molecules in each human cell are constantly being di
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JCI: Using DNA methylation to trace the source of free DNA cells in blastocyst culture fluid
Time of Update: 2021-08-09
2. There is free DNA contamination from embryonic polar body cells in the free DNA of embryo culture fluid In order to further explore the accurate source of free DNA in the SECM without granule cell contamination, the study continued to conduct a systematic unsupervised cluster analysis of the methylation of free DNA in the culture medium and the genomic methylation of preimplantation embryo cells.
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Who said that being too clean will damage the immunity of children
Time of Update: 2021-08-05
In a paper published in the Journal of Allergy and Clinical Immunology, the researchers pointed out four important reasons.
