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Nearly half of drug-resistant lung cancer patients have been relieved, and innovative precision therapies have demonstrated anti-cancer efficacy
Time of Update: 2022-11-05
Data analysis showed that NVL-520 has a good safety profile and tolerability, and shows preliminary efficacy in those patients with ROS1-positive non-small cell lung cancer (NSCLC) who have undergone a large number of pre-treatment, including those with brain metastases and G2032R resistance variants.
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Cancers: Research status of dual-target CAR-T cell therapy
Time of Update: 2022-10-31
Currently, in preclinical models and clinical trials of hematological malignancies, there are at least three combinations of antigens for dual-target CAR-T cell therapy: CD19/CD20, CD19/CD22, and BCMA/CD38.
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The treatment of thalassaemia is a small test, and the future application of gene editing is beginning to appear Industry observation
Time of Update: 2022-10-20
Differences between the two treatments Differences between the two treatments In the opinion of industry experts, an important reason for the industry's attention to gene editing treatment of thalassaemia is to avoid the possible carcinogenic risk caused by random integration of lentiviral (LVV).
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【Guidelines and Consensus】Guidelines for the diagnosis and treatment of thyrotoxicosis caused by hyperthyroidism and other causes in China (Part I
Time of Update: 2022-10-19
Part 1 Background： ， 。 ， ， summaryHyperthyroidism (hyperthyroidism) is a common disease of the endocrine system, and in order to standardize the clinical diagnosis and treatment of hyperthyroidism in China, five societies have jointly formulated this guideline.
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Cell: Dr. Yang Daping et al. found that pain has an unexpected direct protective effect
Time of Update: 2022-10-19
This study shows that the pain-receptor nerves in the gut are normally able to regulate the presence of protective mucus and stimulate goblet cells in the intestine to secrete more mucus in an inflammatory state, thereby directly protecting the intestines.
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Intens Care Med: Distal ischemic adaptation in patients with septic shock
Time of Update: 2022-09-30
Recently, a research article was published in Intensive Care Medicine, an authoritative journal in critical care medicine, the purpose of which was to determine whether distal ischemic adaptation (RECO) improves the severity and outcome of multi-organ failure in patients with septic shock compared with standard treatment.
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Latest Consensus! USPSTF Screening Recommendations for Adolescents with "Prediabetes/Type 2 Diabetes
Time of Update: 2022-09-21
S. Preventive Services Task Force (USPSTF) issued a statement to JAMA: There is currently insufficient evidence to assess the benefits and risks on the question of whether screening for prediabetes and type 2 diabetes should be conducted for asymptomatic children and adolescents.
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Hyperthyroidism, not only related to nail work
Time of Update: 2022-09-20
Preface"Headache cure head, foot pain heal foot" is used to describe inexperienced doctors, but there are also patients who have such one-sided ideas in the treatment of diseases. Sometimes this kind
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Look for signs when buying health food
Time of Update: 2022-09-17
(Editor Li Chuang) With the improvement of living standards, many consumers, especially elderly consumers, have a demand for health food .
(Editor Li Chuang) With the improvement of living standards, many consumers, especially elderly consumers, have a demand for health food .
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In Addition to neurons, astrocytes seriously interfere with brain diseases
Time of Update: 2022-09-08
In the new study, Allen and colleagues isolated astrocytes and neurons from the developing brains of mice with genetic mutations that cause Rett, Fragile X or Down syndrome or from healthy animals.
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The NAR-He/Su Zhida team found that topoisomerase IIA can regulate adult neurogenesis in the subependymal region
Time of Update: 2022-09-07
On August 27, 2022, Professor He Cheng and Professor Su Zhida of naval military medical university published a study entitled "Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37" at the biomedical journal Nucleic Acids Research.
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A&R: Neutrophil-lymphocyte ratio and platelet-lymphocyte ratio as biomarkers for axial spondylitis
Time of Update: 2022-09-06
42333 OBJECTIVE: To assess the utility of neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in predicting disease activity in sacroiliitis imaging and axial spondyloarthritis (axSpA) and compare it with conventional The use of tumor necrosis factor inhibitors (TNFi) was investigated in relation to these laboratory values compared with inflammatory markers .
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An article to understand HER2-targeted therapy for colorectal cancer
Time of Update: 2022-08-12
Second, about 10% to 15% of gastric cancer patients have HER2 amplification, and anti-HER2-targeted drugs combined with chemotherapy have achieved very good results in these patients .
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European Radiology: Application of radiological nomogram in preoperative differentiation of cHCC-CC and ICC
Time of Update: 2022-05-21
In conclusion, this study proposes a radiomic nomogram incorporating radiomic features and clinical factors as a noninvasive imaging tool for preoperative differentiation of cHCC-CC and IMCC .
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Haisco's innovative drug HSK36212 capsule received the "Notice of Acceptance" for clinical trial application
Time of Update: 2022-03-06
Preclinical studies have shown that HSK36212 capsules can inhibit the expression of genes related to renal injury and fibrosis at the molecular level in animal models of acute kidney injury and chronic kidney disease; Reducing the inflammatory response, in the detection of renal biochemical function, can increase the UPCR ratio and improve blood biochemical indicators, showing a huge potential for the treatment of renal disease .
