"PNAS" why diabetes is closely related to severe COVID-19
Time of Update: 2021-09-11
Starting with a mouse model of coronavirus infection, they found that SETDB2 was reduced in immune cells called macrophages in the inflammatory response of diabetic mice .
"To verify this, the research team injected interferon into diabetic mice infected with coronavirus and found that they can increase SETDB2 and reduce inflammatory cytokines .
Lutein esters are widely used in which industries
Time of Update: 2021-09-04
At this time, if you can take some nutrients containing lutein, which can effectively filter blue light, you can protect the retina of infants and young children .
Nat Commun: Smad4 deletion inhibits PAK3 expression and promotes metastasis of invasive lung cancer
Time of Update: 2021-08-26
Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation .
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Chinese genome research ranks among the top in the world
Time of Update: 2021-07-31
June 26, China Kexue Yuan Institute of Genetics and Developmental Biology, Chinese Kexue Yuan Beijing Genomics Institute (National Center for Biotechnology Information) and BGI jointly organized the "celebration of the International Human Genome job sketching and '1% of the projects' completion forum "Review the development history of genomics, and promote the faster and better development of life sciences in our country .
"Good cholesterol" can protect the liver
Time of Update: 2021-07-27
Randolph, a professor of immunology at the University of Washington School of Medicine, one of the corresponding authors of the study, said that the study showed that increasing the level of this specific type of HDL, especially in the intestine, may have a protective effect on liver disease .
To "turn" mutant proteins into healthy proteins, Liu Ruqian's team's latest "Nature" brings new breakthroughs in gene therapy
Time of Update: 2021-06-11
Using the single-base editing method, the team provides a new idea for gene therapy, which is expected to open up a whole new world of rare genetic disease treatment.
Nature: Nod2 gene defect inhibits effective recovery of intestinal fibrosis and inflammation, leading to Crohn's disease
Time of Update: 2021-05-07
The author tried to understand what caused the inflammation and fibrosis of Crohn's disease, and through the use of human cells, human intestinal tissues and zebrafish models to conduct research to link these biological insights with NOD2.
JCI: Scientists have discovered a new potential target for treating autoimmune diseases
Time of Update: 2020-11-04
Therefore, controlling the number and activity of Tregs is particularly important for maintaining the health of the body; in a recent study published in the international journal Journal of Clinical Investigation, scientists from institutions such as the University of Pennsylvania found that by targeting molecules called DEL-1 or as an effective way to help treat inflammation or suppress autoimmune responses, DEL-1 molecules promote Tregs and its immunosuppressive activity.
Developing a Minimally Immunogenic Humanized Antibody by SDR Grafting
Time of Update: 2020-11-02
Early attempts to reduce the HAMA response led to the development of mouse-human chimeric MAbs that are generated by replacing the constant regions of the heavy and light chains of the murine antibodies with those of the human antibodies ( 5 ).
Nat Med: Watch out! Heart disease significantly increases mortality in breast cancer patients
Time of Update: 2020-07-28
NEW YEAR'S DAY -- Breast cancer patients are more likely to die of cancer after a heart attack, a new study finds The study, led by researchers at New York University's Grossman School of Medicine, re
Sosei announces that its first drug, HTL0014242, has been developed
Time of Update: 2020-06-10
Recently, Japan's bio medicine (http:// giant Sosei announced that the first subject stake has taken its drug (http:// HTL0014242, a new type of small molecule compound, this test (http://
Scientists make important progress as macromolecules break through blood-brain barrier
Time of Update: 2020-06-06
Science Translational Medicine, a sub-journal of Science, also reports on two research papers published by Denali Spas In the paper, the biotech company introduces a new technology that could help
How do bacteria "attack" in the body? Another bacterial strategy has been deciphered
Time of Update: 2020-05-31
Researchers at the University of Cologne in Germany have found that certain bacteria prevent apoptosis by inhibiting the activity of the effect cystic winter enzyme, which allows them to camp in cells
Nat Genet: Add hammer evidence! Parkinson's disease or really starts in the gut
Time of Update: 2020-05-12
May 12, 2020 /PRNewswire BIOON/Researchers at the Karolinska Institute in Sweden and the University of North Carolina in the United States have mapped the types of cells behind various brain diseas