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Pancreaticoduodenal sulcus – disease types and imaging findings
Time of Update: 2023-01-05
(B) Coronal contrast-enhanced CT image showing thickened and weakly strengthened mass in the descending duodenal wall, marked narrowing of the corresponding intestinal lumen (white arrow), obstruction caused by an "apple core"-like lesion, and marked dilation of the stomach and duodenal bulb (black arrow).
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26 common autoimmune diseases
Time of Update: 2023-01-04
To date, more than 80 autoimmune diseases have been identified, ranging from systemic (such as systemic lupus erythematosus, which can affect the skin, joints, kidneys, and central nervous system, etc.
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Afternoon review of Shanghai rubber market on August 29
Time of Update: 2022-12-12
From the perspective of Shanghai rubber trend, for the key support area 12300-12400 area, yesterday repeatedly stepped back to test, although the inertia was broken, but the evening re-run above the area, corresponding to the continuation of the upward trend of washing.
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Prysmian introduces new high-density thin-diameter fibre optic cables
Time of Update: 2022-11-17
(This article is translated from the cable network international station please indicate the source for reprinting) On Wednesday, Prysmian Group, a global leader in high-tech cables and systems for energy and communications, announced the development of a 96 fibre optic cable that will lead the design concept for fine-diameter fibre optic cables.
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Test methods for gas permeability and gas transmittance coefficient of thin films and flakes
Time of Update: 2022-10-02
The lower part is a low-pressure chamber used to store the permeable gas and determine the pressure difference before and after the breathability process to calculate the gas transmission of the specimen.
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Mini pigs cloned from skin cells offer new perspectives on the treatment of Alzheimer's disease
Time of Update: 2022-10-01
, which will make it possible to test new drugs that could be used early on to prevent sorl1-related Alzheimer's disease," said Associate Professor Olav Michael Andersen, first author of the study.
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J Neuroinflammation: Lowering blood cholesterol does not affect neuroinflammation in experimental autoimmune encephalomyelitis
Time of Update: 2022-03-04
We evaluated the role of circulating cholesterol in a mouse model of experimental autoimmune encephalomyelitis (EAE) disease MS using two different approaches: (1) familial hyperlipidemia caused by low-density lipoprotein receptor (LDLR) deficiency A mouse model of cholesterolemia; (2) the use of the anti-PCSK9 neutralizing antibody alirocumab, which reduces the degradation of LDLR, thereby lowering blood cholesterol levels .
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Cancers (Basel): Screening leads to an overestimation of thyroid dysfunction and the relationship between thyroiditis and thyroid cancer risk
Time of Update: 2021-12-27
Figure 1 The adjusted odds ratio of thyroid cancer in the group analysis of Study I: (A) age, gender, income and residential area, (B) hypothyroidism, hyperthyroidism, thyroiditis, autoimmune thyroiditis and Graves disease, ( C) Body mass index obesity, smoking status and frequency of drinking, and (D) CCI, total cholesterol, and systolic blood pressure, Figure 2 .
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Brain: TSPO PET helps to monitor and identify progressive multifocal leukoencephalopathy
Time of Update: 2021-11-13
post-IRIS-PMLIn fact, in 3 patients, treatment with rituximab did not affect the uptake of the tracer in the designated PML lesions after Natalizumab-related PML treatment, but multiple sclerosis in the designated active phase Restore the tracer intake to the baseline level in the symptomatic lesions .
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Use clinical and genomic data to predict the effects of immunotherapy
Time of Update: 2021-11-12
According to research results published in Nature Biotechnology, its performance is significantly better than individual biomarkers or other variable combinations developed so far-in retrospective analysis, the model is predicting the effect of immunotherapy In terms of clinical response, it has achieved high sensitivity and specificity, and can predict overall survival and progression-free survival in the test data of different cancer types .
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Over 20 billion U.S. dollars
Time of Update: 2021-09-05
Note: The indications of drugs can include multiple disease areas; early products without specific projects are considered pre-clinical in the research and development stage; the rare diseases listed in the chart are TTR amyloidosis and maple syrupuria (data source: medical Rubik's Cube NextPharma®)Key domestic/cross-border transactionsKey domestic/cross-border transactions1.
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PNAS: Key cell groups mediate the persistent autoimmune response of the central nervous system
Time of Update: 2021-06-08
(Figure 2, CD11c Cre +/- ITGA4fl/fl mouse EAE disease progression is significantly improved compared to wild type ) On this basis, the author compared this finding with clinical patient information.
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Roche continues to be impacted by biosimilars in the first quarter, total sales of oncology business drops 19
Time of Update: 2021-05-09
Avastin's sales during the quarter fell sharply by 42% to 863 million Swiss francs.
Roche recently released the results of a first-in-class positive study showing that Tecentriq can prevent postoperative recurrence or death in patients with early-stage non-small cell lung cancer.
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Using Reverse Genetics to Develop Small Knockout Collections for Specific Biological Questions
Time of Update: 2021-01-15
With the advent of indexed mutagenized insertion lines in Arabidopsis, it is now possible to order small knockout collections of particular genes to probe a question of biological interest.
This first requires querying Arabidopsis databases to identify lines of interest, ordering them and then verifying homozygous lines to make your collection.
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Detection of Neurocan in Cerebrospinal Fluid
Time of Update: 2020-12-09
Cerebrospinal fluid (CFS) is the most easily accessible component of the human central nervous system and has been successfully used for the analysis of disease-associated molecular imbalances, particularly for extracellular matrix components.
