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Why immunotherapy works for some cancer patients and not others
Time of Update: 2022-11-05
In an analysis of a phase 2 clinical trial of the immunotherapy drug pembrolizumab in 24 patients with endometrial cancer, the Yale team found that the specific mechanism of DNA repair defects in tumors was a key determinant of patient outcomes.
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BJH: allogeneic hematopoietic cell transplantation in patients with relapsed/refractory anaplastic large-cell lymphoma
Time of Update: 2022-09-30
Non-recurrence mortality (NRM), disease modeled recurrence/progression (REL), progression-free survival (PFS), and overall survival (OS) using the Cox proportional risk model.
Non-recurrence mortality (NRM), disease modeled recurrence/progression (REL), progression-free survival (PFS), and overall survival (OS) using the Cox proportional risk model.
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Tsinghua University Reveals the Important Function of the Mechano-receptor Piezo1 in the Mechanosensing of the Central Nervous System
Time of Update: 2022-08-19
" "Astrocytic Piezo1-mediated mechanotransduction determines adult neurogenesis and cognitive functions", revealed that Piezo1, as a mechanosensor of astrocytes, can convert mechanical signals into chemical signals, and participate in the regulation of adult hippocampus by affecting ATP release The important role of neurogenesis and cognitive function provides evidence for the involvement of mechanosignaling in regulating brain tissue homeostasis .
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Wuhan Botanical Garden of Chinese Academy of Sciences has made progress in remote sensing monitoring of forest biodiversity
Time of Update: 2022-08-12
Focusing on cutting-edge issues related to forest diversity monitoring, the Wuhan Botanical Garden Systems Ecology Research Team of the Chinese Academy of Sciences, the team of Professor Penghua Qiu from the School of Geography and Environment of Hainan Normal University, and the team of Professor Wan Bo from the School of Geography and Information Engineering of China University of Geosciences carried out a series of studies .
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JCO: Digital Breast Cancer Course Management Based on Electronic Patient-Reported Outcome (ePRO) Monitoring and Automated Management of Intervention Reminders (eRAPID Study
Time of Update: 2022-05-22
The eRAPID system combines ePRO symptom reporting with customized clinical algorithms to provide patients with automated, severity-based recommendations to support patients in self-management or contacting the hospital .
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The team of Professor Gao Feng and Professor Xianghui Yu isolated anti-HIV-1 broad-spectrum neutralizing antibodies from a rhesus monkey model, and revealed that such antibodies mature
Time of Update: 2022-04-26
The research team of Professor Gao Feng and Professor Yu Xianghui from the School of Life Sciences of Jilin University took the rhesus monkey animal model with the longest reported infection time as t
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Wuhan Botanical Garden makes progress in research on plant litter decomposition
Time of Update: 2022-04-25
Wuhan Botanical Garden graduate student Denis Mburu Njoroge and his collaborators conducted a meta-analysis of published studies around the world to explore the effects of litter diversity and soil animals on decomposition rates .
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Scientists in Birmingham have discovered a new blood coagulation puzzle
Time of Update: 2021-09-04
The receptor targets are known, but mouse studies have shown that recombinant mouse S100A8/A9 induces the formation of procoagulant platelets through GPIbα receptors, which have never been described as S100A8/A9 before.
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Theranostics discovered the role and mechanism of liver miR-378 in regulating serum total cholesterol
Time of Update: 2021-08-11
On February 25, 2021, Ying Hao's research group at the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences published a research result entitled "Hepatic miR-378 modulates serum cholesterol levels by regulating hepatic bile acid synthesis" in Theranostics , and applied for Two patents (202110098302.
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Dalian Rick: Focus on the main business, be specialized, refined and strong
Time of Update: 2021-08-04
It is a service-oriented high-tech enterprise co-founded by the main scientific research personnel of the former National Catalytic Engineering Center, focusing on synthesis gas chemical catalysts and new materials, and integrating R&D, production, sales and technical services .
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The Han Fangpu research group has made new progress in the study of plant centromeres
Time of Update: 2021-08-02
In order to further understand the distribution characteristics of the R-loop structure in the repetitive sequence of the centromere region, the research group used the ssDRIP-seq technology to conduct the mapping of the whole genome R-loop map of maize for the first time .
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Gao Fu and others review how Qingdao dockers were infected with the new crown
Time of Update: 2021-07-30
In fact, on October 17th last year, the official website of the China Centers for Disease Control and Prevention announced that, in the process of the traceability investigation of the new crown pneumonia epidemic in Qingdao, the China Centers for Disease Control and Prevention tested positive samples from the outer packaging of imported frozen cod carried by workers.
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SCIENCE: Fecal microbiota transplantation may help eliminate resistance to immunotherapy in patients with melanoma
Time of Update: 2021-06-16
This study proves that it is possible to reprogram the tumor microenvironment to manipulate the microbiome to enhance and improve the immunotherapy effect of advanced melanoma and overcome anti- PD-1 resistance .
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This genetic mutation can make people 4 cm shorter
Time of Update: 2021-02-18
To determine the factors that affect the height of Peruvians, the researchers collected data on the height and genome of 3,134 people from 1947 families in Lima, Peru.
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May 2020 China's class 1 new drug clinical development
Time of Update: 2020-08-03
May 2020, a total of 19 Chinese Class 1 chemical drugs were approved by the State Drug Administration (NMPA) for clinical trials, as shown in the table below: SPH-4336 developed by Shanghai Pharmaceuticals and in the clinical phase of the treatment of advanced solid tumors.
