Clin Cancer Res: Tumor infiltrating B cells can predict the clinical prognosis of melanoma patients treated with dabrafenib + trametinib
Time of Update: 2021-08-26
Although patients with unresectable or metastatic melanoma using BRAF and MEK targeted drugs or immune checkpoint inhibitors can treat long-term survival of more than 5 years, most patients will devel
Trends Cancer: Targeting the gut microbiota to treat colitis caused by immunotherapy in cancer patients
Time of Update: 2021-03-30
Butyrate has an anti-inflammatory effect in the colon, so it may have a protective effect against colitis / diarrhea caused by ICI .
Cell sub-journal: A miRNA can improve insulin sensitivity in obese mice
Time of Update: 2021-02-11
miR-690 is an insulin-sensitive tiny ICT, and experiments have shown that anti-inflammatory M2-like bone marrow substituts express more miR-690, while M2 Exos is more abundant in the metabolic tissue of obese mice fed HFD for 4 weeks.
Cell Metabolism: Significant progress! Chi Hongbo's team revealed metabolic mechanisms that regulate Treg cells or provide new targets for autoimmune disease therapy
Time of Update: 2020-12-14
addition, the authors identified specific catalytic effects of Fntb on mTORC1 activity and ICOS expression to maintain eTreg cells, while Pggt1b mediates TCR activation and Rac signal conduction eTreg cell differentiation.
Pregnancy combined mechanical valve acute dysfunction retains pregnancy re-valve anaesthetic in case
Time of Update: 2020-06-21
Pregnant women, 35 years old, 160 cm, 70 kg, pregnant 28 plus weeks, due to "stopped for 28 plus weeks, panic, chest tightness, wheezing 2d" hospital 14 years ago due to rheumatic heart disease two-
The research team of Professor Wang Shilong from Tongji University reveals the molecular mechanism of nano layered double hydroxides as functional carriers to reduce the embryotoxicity induced
Time of Update: 2019-12-15
Recently, Professor Wang Shilong's research group of Tongji University published a research paper entitled "layered double hydroxide ultimate economy of chemotherapeutical drug through bmp-smad signal